Results 31 to 40 of about 1,027,672 (251)
CD36 c.1264 T>G Null Mutation Impairs Acquisition of IgG Antibodies to Plasmodium falciparum MSP1‐19 Antigen and is Associated with Higher Malaria Incidences in Tanzanian Children [PDF]
Scandinavian Journal of Immunology, 2011 AbstractPolymorphisms in genes that encode crucial signalling molecules have been proposed as factors that influence susceptibility to, and outcome of malaria. We studied the role of a mutation, c.1264 T>G, that causes CD36 deficiency on IgG responses to MSP‐119 antigen and malaria incidence. Children were genotyped for the c.1264 T>G mutation at
Debora C. Kajeguka +7 more
openalex +4 more sources
Mathematical Modeling Insights into Improving CAR T cell Therapy for Solid Tumors: Antigen Heterogeneity and Bystander Effects [PDF]
npj Systems Biology and Applications, 10(1), 105 (2024), 2023 As an adoptive cellular therapy, Chimeric Antigen Receptor T-cell (CAR T-cell) therapy has shown remarkable success in hematological malignancies, but only limited efficacy against solid tumors. Compared with blood cancers, solid tumors present a unique set of challenges that ultimately neutralize the function of CAR T-cells.
arxiv +1 more source
Transfusion, 2022 To the Editor, CD36 deficiency is responsible for CD36 iso-immunizations following pregnancy causing fetal and neonatal alloimmune thrombocytopenia (FNAIT) and sometimes early fetal loss or platelet transfusion, inducing platelet transfusion ...
P. Pedini +13 more
semanticscholar +1 more source
Journal of Investigative Dermatology, 1995 Antigen-presenting (APC), suppressor T-cell-inducing macrophages infiltrate both human and murine epidermis after ultraviolet radiation (UVR) exposure. To determine their derivation, we prepared epidermal cell and dermal cell suspensions from human keratome biopsy specimens obtained from nonexposed skin and from UVB-irradiated sites (3 d after four ...
Laurent Meunier +2 more
openalex +3 more sources
CD36 Signal Transduction in Metabolic Diseases: Novel Insights and Therapeutic Targeting
Cells, 2021 The cluster of differentiation 36 (CD36) is a scavenger receptor present on various types of cells and has multiple biological functions that may be important in inflammation and in the pathogenesis of metabolic diseases, including diabetes.
Udayakumar Karunakaran +3 more
doaj +1 more source
Nanoparticles Containing Curcumin Useful for Suppressing Macrophages In Vivo in Mice. [PDF]
PLoS ONE, 2015 To explore a novel method using liposomes to suppress macrophages, we screened food constituents through cell culture assays. Curcumin was one of the strongest compounds exhibiting suppressive effects on macrophages. We subsequently tried various methods
Chie Amano +6 more
doaj +1 more source
Clinical implications of CD36 antigen/antibody in allogeneic hematopoietic stem cell transplantation
Japanese Journal of Transplantation and Cellular Therapy, 2023 Hirokazu Tsuno +7 more
openalex +3 more sources
Frontiers in Cell and Developmental Biology, 2021 Lipid-related disorders, which primarily affect metabolic tissues, including adipose tissue and the liver are associated with alterations in lysosome homeostasis.
Fernanda Cabrera-Reyes +5 more
doaj +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Immunomodulatory cross-talk between conjunctival goblet cells and dendritic cells. [PDF]
PLoS ONE, 2015 Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from environmental agents or pathogens via expression and secretion of soluble mucins.
Laura Contreras-Ruiz, Sharmila Masli
doaj +1 more source