CD24, CD27, CD36 and CD302 gene expression for outcome prediction in patients with multiple myeloma
Multiple myeloma (MM) is a B cell neoplasia characterized by clonal plasma cell (PC) proliferation. Minimal residual disease monitoring by multi-parameter flow cytometry is a powerful tool for predicting treatment efficacy and MM outcome.
E. Alaterre +10 more
semanticscholar +1 more source
Objectives: To explore whether individuals infected with Plasmodium falciparum (P. falciparum) develop antibodies directed against PfEMP1-DBLα, and to assess their IgG subclass distribution in severe and uncomplicated malaria. Methods: The anti-PfDBLα
Natharinee Horata +4 more
doaj +1 more source
A case of platelet transfusion refractoriness due to anti-CD36 with a successful treatment outcome
Antibodies (Abs) against antigens on platelets (PLTs), including glycoprotein IV (CD36), can cause PLT refractoriness. Transfusing PLTs to patients with anti-CD36 is challenging because of the rarity of CD36-negative (CD36–) donors and the possibility of
S. Khatri, B. Curtis, C. Yamada
semanticscholar +1 more source
Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria [PDF]
Cytoadhesion of Plasmodium falciparum infected erythrocytes to gC1qR has been associated with severe malaria, but the parasite ligand involved is currently unknown.
Aide, Pedro Carlos Paulino +20 more
core +3 more sources
Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. [PDF]
The initiation of adaptive immune responses to protein antigens has to be preceded by their uptake by antigen presenting cells and intracellular proteolytic processing.
Rafał Biedroń +3 more
doaj +1 more source
Decrease of Very Late Activation Antigen-4 and CD36 on Reticulocytes in Sickle Cell Patients Treated With Hydroxyurea [PDF]
Abstract Sickle cell disease (SCD) is characterized by repeated vaso-occlusive events, which result in substantial morbidity. Abnormal adhesion of sickle red blood cells (RBC) to the vascular endothelium is postulated to play a role in the pathogenesis of vaso-occlusion.
L A, Styles +6 more
openaire +2 more sources
The regulation of B cell responses in systemic autoimmunity [PDF]
Our immune system is a complex network made up of physical barriers and specialized proteins, cells and organs that all work together to prevent pathogens from causing disease in the body.
Duhlin, Amanda
core +1 more source
Surface antigens in Plasmodium falciparum malaria : PfEMP1 and SURFIN4.2 [PDF]
Plasmodium falciparum malaria is an infectious disease that on despite of the ongoing eradication efforts is still endemic in more than 100 countries, sometimes causing severe disease that leads to the death of around half a million people per year ...
Quintana Varon, Maria del Pilar
core +1 more source
src‐related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells [PDF]
src‐related cytoplasmic PTKs are physically and functionally associated with cell surface receptors and are involved in signal transduction. In this paper we report the identification of src‐related proteins p59 fyn , pp60c‐scr and p62 yes in human microvascular endothelial cells cultured from normal human skin and their physical association with ...
Bull, Helen A. +2 more
openaire +2 more sources
Impact of intermittent preventive anti-malarial treatment on the growth and nutritional status of preschool children in rural Senegal (west Africa). [PDF]
Negative consequences of malaria might account for seasonality in nutritional status in children in the Sahel. We report the impact of a randomized, double-blind, placebo-controlled trial of seasonal intermittent preventive anti-malarial treatment on ...
Alexander, Neal +10 more
core +2 more sources

