Results 61 to 70 of about 1,031,952 (237)

Evidence that CD36 is expressed on red blood cells and constitutes a novel blood group system of clinical importance

Vox Sanguinis
Polymorphic molecules expressed on the surface of certain blood cells are traditionally categorized as blood groups and human platelet or neutrophil antigens.
A. Alattar, J. Storry, Martin L. Olsson
semanticscholar   +1 more source

Infectivity of Plasmodium falciparum in malaria-naive individuals is related to knob expression and cytoadherence of the parasite [PDF]

, 2016
Plasmodium falciparum is the most virulent human malaria parasite because of its ability to cytoadhere in the microvasculature. Nonhuman primate studies demonstrated relationships among knob expression, cytoadherence, and infectivity.
Beeson, James G., Chan, Jo-Anne A., Fink, James, Gerrard, John, Good, Michael F., Griffin, Paul M., Hackett, Hazel, Hanssen, Eric, Hoffman, Stephen L., Langer, Christine, Liu, Xue Q., McCarthy, James S., Pingnet, Jolien, Rodriguez, Ingrid B., Sekuloski, Silvana, Stanisic, Danielle I., Sundac, Lana, Trenholme, Katharine R., Wang, Claire Y. T., Yang, Yuedong, Zhou, Yaoqi   +20 more
core   +1 more source

Sickle cell protection from malaria: a review

Hematology Reports, 2011
A linkage between presence of Sickle Haemoglobin (HbS) and protection from malaria infection and clinical manifestations in certain areas was suspected from early observations and progressively elucidated by more recent studies.
Sandro Eridani
doaj   +1 more source

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. [PDF]

, 2018
Oxidized phospholipids (OxPL) are ubiquitous, are formed in many inflammatory tissues, including atherosclerotic lesions, and frequently mediate proinflammatory changes 1 .
Binder, Christoph J, Bowden, Karen, Diehl, Cody, Gaddis, Dalia E, Glass, Christopher K, Gonen, Ayelet, Hedrick, Catherine C, Hung, Ming-Yow, Ley, Klaus, MacDonald, Jeffrey G, Mellon, Pamela L, Miller, Yury I, Määttä, Antti, Pattison, Jennifer, Peterson, Kirk L, Prohaska, Thomas A, Que, Xuchu, Sun, Xiaoli, Tsimikas, Sotirios, Witztum, Joseph L, Yeang, Calvin, Ylä-Herttuala, Seppo   +21 more
core   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Malaria vaccines 1985-2005: a full circle?

, 2005
Few who were actively engaged in malaria vaccine research 20 years ago (including myself) would have imagined that, in 2005, there would still be a prediction of a 10-20-year horizon before vaccines become part of malaria-control strategies.
Targett, Geoffrey A
core   +1 more source

In vitro inhibition of Plasmodium falciparum rosette formation by Curdlan sulfate [PDF]

, 2007
Spontaneous binding of infected erythrocytes to uninfected erythrocytes to form rosettes is a property of some strains of Plasmodium falciparum that is linked to severe complications of malaria.
Arman, Monica, Bull, Peter C, Havlik, Ivan, Kyriacou, Helen M, Raza, Ahmed, Rowe, J Alexandra, Steen, Katie E, Warimwe, George   +7 more
core   +2 more sources

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

The Gates Malaria Partnership: a consortium approach to malaria research and capacity development.

, 2012
Recently, there has been a major increase in financial support for malaria control. Most of these funds have, appropriately, been spent on the tools needed for effective prevention and treatment of malaria such as insecticide-treated bed nets, indoor ...
Bhasin, Amit, Greenwood, Brian, Targett, Geoffrey   +2 more
core   +1 more source

Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria [PDF]

, 2016
Cytoadhesion of Plasmodium falciparum infected erythrocytes to gC1qR has been associated with severe malaria, but the parasite ligand involved is currently unknown.
Aide, Pedro Carlos Paulino, Alonso, Pedro, Bassat Orellana, Quique, Chitnis, Chetan E., Cisteró, Pau, Gascón i Brustenga, Joaquim, Gupta, Himanshu, Jiménez, Alfons, Lavstsen, Thomas, Macete, Eusebio Víctor, Machevo, Sonia, Magallón Tejada, Ariel, Mandomando, Inácio, Mayor Aparicio, Alfredo Gabriel, Muñoz, José, Petersen, Jens E. V, Rubio, Mercedes, Salas, Briege de las, Turner, Louise, Valmaseda, Aida, Wang, Christian W.   +20 more
core   +3 more sources