Results 1 to 10 of about 91,216 (142)

Vitamin D receptor expression in germinal centre type diffuse large B-cell lymphoma cells is associated with vitamin D insensitivity [PDF]

Endocrine Oncology
Objective: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of non-Hodgkin lymphomas (NHLs) often sub-classified into major germinal centre (GC) and activated B-cell (ABC) cell-of-origin types.
Elizabeth J Soilleux, Amanda Anderson, Emma Roberts, Linden Lyne, Kah Keng Wong, Hayley Spearman, Stefano Casola, Alison H Banham, Duncan M Gascoyne   +8 more
doaj   +2 more sources

Cortisol patterns are associated with T cell activation in HIV. [PDF]

, 2012
ObjectiveThe level of T cell activation in untreated HIV disease is strongly and independently associated with risk of immunologic and clinical progression. The factors that influence the level of activation, however, are not fully defined.
Acree, Michael, Bacchetti, Peter, Deeks, Steven G, Epel, Elissa, Epling, Lorrie, Hecht, Frederick M, Kemeny, Margaret E, Kirschbaum, Clemens, Moran, Patricia, Patterson, Sarah, Sinclair, Elizabeth   +10 more
core   +19 more sources

Decrease of CD38 expression is linked to increase of solitary plasmacytoma pathological grade: a single institution experience from China

Frontiers in Bioscience-Landmark, 2022
Introduction: Solitary plasmacytoma (SP) is a rare plasma cell disorder characterized by localized neoplastic proliferation of monoclonal plasma cell. Due to its rarity, further understanding of the spectrum of its clinicopathologic features is needed ...
Yueying Li, Jianchun Guo, Chunxiu Yang, Jian Xu, Pei Meng, Shu-Yuan Xiao   +5 more
doaj   +1 more source

Evaluation of Relationship between CD38 Expression and Gleason Score in Prostatic Carcinoma [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Prostate cancer is the most prevalent non-cutaneous malignancy in men. The Gleason grading system is an important prognostic factor in prostatic carcinoma.
Mohsen Besharati Rad, Mohammadreza Jalali Nadoushan   +1 more
doaj  

Harnessing the Power of CAR-NK Cells: A Promising Off-the-Shelf Therapeutic Strategy for CD38-Positive Malignancies [PDF]

Iranian Journal of Immunology, 2023
Background: CD38 is highly expressed on multiple myeloma (MM) cells and has been successfully targeted by different target therapy methods. This molecule is a critical prognostic marker in both diffuse large B-cell lymphoma and chronic lymphocytic ...
Maryam Asadi, Razie Kiani, Vahid Razban, Seyed Faraji, Amirhossein Ahmadi, Jafar Fallahi, Amin Ramezani, Nasrollah Erfani   +7 more
doaj   +1 more source

Jujuboside a improved energy metabolism in senescent H9c2 cells injured by ischemia, hypoxia, and reperfusion through the CD38/Silent mating type information regulation 2 homolog 3 signaling pathway

World Journal of Traditional Chinese Medicine, 2023
Objective: This study explored the myocardial protection role of Jujuboside A through an ischemia–hypoxia–reperfusion (IHR) model. Materials and Methods: H9c2 cells were induced by D-galactose (D-gal) and IHR to establish an aging and IHR model.
Yi-Ran Hu, Hui-Yan Qu, Jia-Ying Guo, Tao Yang, Hua Zhou   +4 more
doaj   +1 more source

Immune Phenotype and Functionality of Mtb-Specific T-Cells in HIV/TB Co-Infected Patients on Antiretroviral Treatment

Pathogens, 2020
The performance of host blood-based biomarkers for tuberculosis (TB) in HIV-infected patients on antiretroviral therapy (ART) has not been fully assessed.
Lucy Mupfumi, Cheleka A.M. Mpande, Tim Reid, Sikhulile Moyo, Sanghyuk S. Shin, Nicola Zetola, Tuelo Mogashoa, Rosemary M. Musonda, Ishmael Kasvosve, Thomas J. Scriba, Elisa Nemes, Simani Gaseitsiwe   +11 more
doaj   +1 more source

Expression of microRNA-155 in circulating T cells is an indicator of immune activation levels in HIV-1 infected patients

HIV Research & Clinical Practice, 2021
Objectives: MicroRNA-155 (miR-155) regulates activation of T cells. However, its relationship with T-cell immune activation level in human immunodeficiency virus (HIV) patients remains unclear.
Zhenghao Zhang, Yong Wu, Jiangnan Chen, Fangqing Hu, Xuefang Chen, Wenfang Xu   +5 more
doaj   +1 more source

Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs)

Cells, 2020
The NAD-hydrolyzing ecto-enzyme CD38 is overexpressed by multiple myeloma and other hematological malignancies. We recently generated CD38-specific nanobodies, single immunoglobulin variable domains derived from heavy-chain antibodies naturally occurring
Julia Hambach, Kristoffer Riecken, Sophia Cichutek, Kerstin Schütze, Birte Albrecht, Katharina Petry, Jana Larissa Röckendorf, Natalie Baum, Nicolaus Kröger, Timon Hansen, Gunter Schuch, Friedrich Haag, Gerhard Adam, Boris Fehse, Peter Bannas, Friedrich Koch-Nolte   +15 more
doaj   +1 more source

The high-performance technology CRISPR/Cas9 improves knowledge and management of acute myeloid leukemia

Biomedical Papers, 2021
Knowledge on acute myeloid leukemia pathogenesis and treatment has progressed recently, but not enough to provide ideal management. Improving the prognosis of acute myeloid leukemia patients depends on advances in molecular biology for the detection of ...
Romeo Gabriel Mihaila, Diana Topircean
doaj   +1 more source