Results 11 to 20 of about 91,544 (273)
CD38 in Neurodegeneration and Neuroinflammation [PDF]
Cells, 2020 Neurodegenerative diseases are characterized by neuronal degeneration as well as neuroinflammation. While CD38 is strongly expressed in brain cells including neurons, astrocytes as well as microglial cells, the role played by CD38 in neurodegeneration ...
Serge Guerreiro +3 more
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Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on CD38 (CD38 molecule), with data on DNA, on the protein encoded, and where the gene is implicated.
Deaglio, S, Vaisitti, T
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CD38 in Advanced Prostate Cancers [PDF]
European Urology, 2021 Background CD38, a druggable ectoenzyme, is involved in the generation of adenosine, which is implicated in tumour immune evasion. Its expression and role in prostate tumour-infiltrating immune cells (TIICs) have not been elucidated. Objective To characterise CD38 expression on prostate cancer (PC) epithelial cells and TIICs, and to associate this
Christina Guo +93 more
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Targeting CD38 for acute leukemia
Frontiers in Oncology, 2022 Acute leukemia (AL) is a hematological malignancy, and the prognosis of most AL patients hasn’t improved significantly, particularly for relapsed or refractory (R/R) AL. Therefore, new treatments for R/R adult acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) are urgently necessary.
Xushu Zhong, Hongbing Ma
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World Journal of Traditional Chinese Medicine, 2023 Objective: This study explored the myocardial protection role of Jujuboside A through an ischemia–hypoxia–reperfusion (IHR) model. Materials and Methods: H9c2 cells were induced by D-galactose (D-gal) and IHR to establish an aging and IHR model.
Yi-Ran Hu +4 more
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HIV Research & Clinical Practice, 2021 Objectives: MicroRNA-155 (miR-155) regulates activation of T cells. However, its relationship with T-cell immune activation level in human immunodeficiency virus (HIV) patients remains unclear.
Zhenghao Zhang +5 more
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Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor treated CML stem cells [PDF]
, 2016 Treatment of chronic myelogenous leukemia (CML) with BCR-ABL tyrosine kinase inhibitors (TKI) fails to eliminate leukemia stem cells (LSC). Patients remain at risk for relapse, and additional approaches to deplete CML LSC are needed to enhance the ...
Agarwal, Puneet +9 more
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CD38, CD157, and RAGE as Molecular Determinants for Social Behavior
Cells, 2019 Recent studies provide evidence to support that cluster of differentiation 38 (CD38) and CD157 meaningfully act in the brain as neuroregulators. They primarily affect social behaviors. Social behaviors are impaired in Cd38 and Cd157 knockout mice. Single-
Haruhiro Higashida +22 more
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Sudan Journal of Medical Sciences, 2020 Background: The clinical course of chronic lymphocytic leukemia is highly variable. The determination of ZAP70 and CD38 is increasingly utilized as prognostic factor for chronic lymphocytic leukemia.
Enaam Abdelrhman Abdelgader +6 more
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Biomedical Papers, 2021 Knowledge on acute myeloid leukemia pathogenesis and treatment has progressed recently, but not enough to provide ideal management. Improving the prognosis of acute myeloid leukemia patients depends on advances in molecular biology for the detection of ...
Romeo Gabriel Mihaila, Diana Topircean
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