Results 41 to 50 of about 276,570 (260)

Tapak liman (Elephantopus scaber L) Extract Induced CD4+ and CD8+ Differentiation from Hematopoietic Stem Cell/Progenitor Cell Proliferation of Mice (Mus musculus)

Journal of Experimental Life Science, 2015
Tapak liman (Elephantopus scaber L) is one of the traditional medicinal plants, which are containing several active compounds that potentially affecting hematopoietic.
M. Sasmito Djati, Hindun Habibu, Nabilah A Jatiatmaja, Muhaimin Rifa'i   +3 more
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Pan-cancer landscape of aberrant DNA Methylation across childhood Cancers: Molecular Characteristics and Clinical relevance

Experimental Hematology & Oncology, 2022
Aberrant DNA methylation (DNAm) is an important epigenetic regulator in various cancers. Pan-cancer DNAm analyses have investigated the potential common mechanisms of DNAm in tumorigenesis.
Zheng Dong, Hongyu Zhou
doaj   +1 more source

Role of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1 [PDF]

, 1997
CD4 is the primary receptor for human immunodeficiency virus (HIV). The binding site for the surface glycoprotein of HIV type 1 (HIV-1), gp120, has been mapped to the C'-C" region of domain 1 of CD4. Previously, we have shown that a mutant of rat CD4, in
Puklavec, M., Stumbles, P.A., James, W., Somoza, C., Signoret, N., Simon, J.H.M, Sattentau, Q.J., Barclay, A.N.   +7 more
core  

CD4-WTLAT traffics from the cell surface to the lysosome in activated cells.

, 2020
A. JCam2.5 cells stably expressing CD4-WTLAT or CD4-2KRLAT were treated with 1mg/ml Leupeptin for 4 hrs. Cells were then labeled with anti-CD4 (clone OKT4) at 4°C, dropped onto stimulatory coverslips at 37°C and fixed after 30 minutes.
Katherine M. McIntire (8478726), Lakshmi Balagopalan (8478720), Lawrence E. Samelson (8478738), Hiba Malik (8478723), Tiffany Nguyen (8478732), Ana B. Rodriguez-Peña (8478735), Joseph A. Garvey (8478729)   +6 more
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CD4 cell count and the risk of AIDS or death in HIV-Infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHERE. [PDF]

, 2012
BACKGROUND: Most adults infected with HIV achieve viral suppression within a year of starting combination antiretroviral therapy (cART). It is important to understand the risk of AIDS events or death for patients with a suppressed viral load.
S. Matheron, M. Sharland, Niels Obel (135891), R. Thiebaut, Jesper Grarup (453101), José M Miro, Reiss, Peter, Furrer, H, D. Haerry, A. Cozzi Lepri, Josefa Muñoz (11702276), Miró Meda, José M. (José María), 1956-, Hansjakob Furrer (93994), Ole Kirk (314889), Gazzard, B, G. Touloumi, Raffi, F, Josefa Muñoz, J. Reekie, A. Castagna, G. Fatkenheuer, R. Lodwick, Niels Obel, Sophie Grabar (697347), S. Grabar, T. Goetghebuer, J. Grarup, The Opportunistic Infections Project Team of the Collaboration o (16174457), D. Gibb, A. Antinori, Peter Reiss (4933), E. Girardi, José M Miro (16174463), Raffi, Francois, Antonella Castagna (255402), Grarup, Jesper, F. Engsig, Peter Reiss, Kirk, Ole, F. Gutierrez, Opportunistic Infections Project Team of the Collaboration of Ob,, H. Furrer, J. Casabona, M. Egger, O. Lambotte, Sylvie Ayayi (16174460), J. Ghosn, V. Bouteloup, Obel, N, Young, Jim, De Wit, Stéphane, Chêne, Geneviève, Heiner Bucher, M. Psichogiou, Mina Psichogiou (146065), Y. Young, C. Stephan, Chêne, G, Martin Fisher (300134), C. Lewden, A. D’Arminio Monforte, Ayayi, Sylvie, R. Zangerle, Young, J, S. De Wit, Laurence Meyer (130347), Bucher, Heiner, Antonella Castagna, Miró, José María, Geneviève Chêne, C. Sabin, Meyer, Laurence, Félix Gutierrez, Miro, José M, P. Morlat, P. Tookey, C. Torti, Gazzard, Brian, R. Paredes, The Opportunistic Infections Project Team of the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord (614233), J. M. Miro, V. Le Moing, I. Weller, Francois Raffi, A. Mocroft, C. Smit, Jim Young (252690), S. Ayayi, Grarup, J, Jesper Kjaer, Sharland, M, Brian Gazzard, M. Prins, J. Warszawski, A. Noguera Julian, M. Garrido, De Wit, S, F. de Wolf, H. Bucher, Muñoz, J, J. Miro, C. Thorne, O. Kirk, Francois Raffi (6269708), Stéphane De Wit, Jesper Grarup, Gutierrez, Félix, J. Kjaer, Kjaer, J, J. Munoz, Bucher, Heiner H.C., Ole Kirk, V. von Wyl, C. Leport, A. Scherrer, L. Galli, Opportunistic Infections Project Team of the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE) in EuroCoord, Kjaer, Jesper, D. Costagliola, J. Sterne, Sophie Grabar, Opportunistic Infections Project Team of the Collaboration of Ob, P. Reiss, F. Dabis, Heiner Bucher (3510056), Meyer, L, A. Antoniadou, Furrer, Hansjakob, Jim Young, J. Ramos, J. Bohlius, A. Phillips, Hansjakob Furrer, Noguera Julian, Antoni, Sylvie Ayayi, Collaboration of Observational HIV Epidemiological Research Europe (COHERE), Castagna, A, Geneviève Chêne (252698), Ayayi, S, Obel, Niels, C. Colin, Bucher, H, F. Raffi, R. Teira, Jesper Kjaer (453100), Castagna, Antonella, Psichogiou, M, L. Meyer, N. Brockmeyer, A. Rauch, G. Chene, Miro, JM, Grabar, Sophie, M. Puoti, Kirk, O, Laurence Meyer, Reekie, Joanne ; https://orcid.org/, Muñoz, Josefa, B. Gazzard, N. Obel, M. M. Krause, J. Del Amo, Mina Psichogiou, L. Wittkop, M. Battegay, Grabar, S, Stéphane De Wit (262489), Brian Gazzard (4921), M. Fisher, Reiss, P, Gutierrez, F, S. Perez Hoyos, M. Dorrucci, Mike Sharland (258810), M. Paulsen, B. Ledergerber, Mike Sharland, Sharland, Mike, Psichogiou, Mina, C. Mussini, Félix Gutierrez (379459), Miró Meda, José M., COHERE EuroCoord European AIDS Treatment Grp   +182 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Imbalanced T-Cell Subsets May Facilitate the Occurrence of Osteonecrosis of the Femoral Head

Journal of Inflammation Research, 2022
Changjun Chen,1 Xin Zhao,1,2 Yue Luo,1 Bohua Li,1 Qianhao Li,1 Chengcheng Zhao,1 Yan Huang,3 Pengde Kang1 1Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Department of Orthopedics, Shandong ...
Chen C, Zhao X, Luo Y, Li B, Li Q, Zhao C, Huang Y, Kang P   +7 more
doaj  

Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy. [PDF]

, 2007
Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer ...
Burdach, S., Witter, K., Boerschmann Heike, Boerschmann, H., Mautner, Josef, Georg W Bornkamm, Adhikary, D., Adhikary, Dinesh, Uta Behrends, Burdach Stefan, Bornkamm, G.W., Mautner, J., Georg W, Andrea Pfünder, Moosmann, A., Witter Klaus, Adhikary Dinesh, Pfünder, Andrea, Dinesh Adhikary, Klaus Witter, Pfünder Andrea, Josef Mautner, Behrends Uta, Stefan Burdach, Moosmann Andreas, Andreas Moosmann, Bornkamm Georg W., Behrends, Uta, Boerschmann, Heike, Burdach, Stefan, Bornkamm, Georg W., Pfünder, A., Witter, Klaus, Behrends, U., Mautner Josef, Moosmann, Andreas, Heike Boerschmann, Adhikary, D;Behrends, U;Boerschmann, H;Pfünder, A;Burdach, S;Moosmann, A;Witter, K;Bornkamm, GW;Mautner, J, Georg W. Bornkamm   +38 more
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The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Effects of Crescentia cujete (L.) fruit extract on the profile of hematology of ranchu goldfish (Carassius auratus)

Open Veterinary Journal
Background: Disease prevention in cultivating ranchu goldfish (Carassius auratus) can be prevented by giving immunostimulants in the food. One immunostimulant can come from herbs such as calabash fruit (Crescentia cujete L.). Aim: This study aims to
Felician Lestari Wongkar, Yos Adi Prakoso, Agustina Dwi Wijayanti   +2 more
doaj   +1 more source