Results 11 to 20 of about 314,352 (325)

CD39 Expression in Peripheral T Cells is Associated with Clinicopathological Characteristics in Patients with Cervical Cancer [PDF]

open access: yesIranian Journal of Immunology, 2023
Background: CD39 is an inhibitory checkpoint exerting rate-limiting effects on the ATP-adenosine pathway. It can be targeted to block adenosine-mediated immunosuppression.Objective: To analyze the relationship between the CD39 expression and ...
Kuo Zhao, Dongmei Han, Lu Tang, Hao Jin
doaj   +1 more source

PEPTIDE SPECIFICITY OF ALLOREACTIVE CD4 POSITIVE T LYMPHOCYTES DIRECTED AGAINST A MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I DISPARITY1

open access: bronzeTransplantation, 1996
The mouse strains C57BL/6 (B6, H2b) and Kbm1 mutant bm1 have a defined difference of three amino acids at position 152, 155, and 156 in the MHC class I K molecule. This causes a change in the side and the bottom of the antigen presenting groove of the K molecule resulting in strong allogeneic responses in vitro and in vivo.
Miriam A. Ossevoort   +4 more
openalex   +4 more sources

Aerobic training modulates T cell activation in elderly women with knee osteoarthritis [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2016
Osteoarthritis of the knee (kOA) is a disease that mainly affects the elderly and can lead to major physical and functional limitations. However, the specific effects of walking, particularly on the immune system, are unknown. Therefore, this study aimed
W.F. Gomes   +7 more
doaj   +3 more sources

Noninvasive Radionuclide Molecular Imaging of the CD4-Positive T Lymphocytes in Acute Cardiac Rejection [PDF]

open access: yesMolecular Pharmaceutics, 2021
Heart transplantation (HT) is an effective treatment for end-stage heart disease. However, acute rejection (AR) is still the main cause of death within one year after HT. AR is an acute immune response mediated by T lymphocytes, mainly CD4+ T lymphocytes.
Huiling Li   +15 more
openaire   +3 more sources

The composition of T cell subtypes in duodenal biopsies are altered in coeliac disease patients [PDF]

open access: yes, 2017
One of the hallmarks of Celiac disease (CD) is intraepithelial lymphocytosis in the small intestine. Until now, investigations to characterize the T cell subpopulations within the epithelial layer have not discriminated between the heterodimeric co ...
Barington, Torben   +8 more
core   +10 more sources

Identification and Characterization of a Master Transcription Factor of Th1 Cells, T-bet, Within Flounder (Paralichthys olivaceus)

open access: yesFrontiers in Immunology, 2021
T-bet, a T-box family member, is a transcription factor essential for the differentiation of naive CD4+ T cells into Th1 cells that are involved in both innate and adaptive immune responses.
Hongfei Tian   +8 more
doaj   +1 more source

Resistin: a newly identified chemokine for human CD4-positive lymphocytes [PDF]

open access: yesCardiovascular Research, 2009
Increased levels of resistin, a peptide secreted by adipocytes and inflammatory cells, circulate in patients with insulin resistance and early type 2 diabetes, a high-risk population for the development of a diffuse and extensive pattern of arteriosclerosis.
Daniel Walcher   +9 more
openaire   +3 more sources

Impaired CD4+ Cytotoxic T Lymphocyte Activity in Polyomavirus BK Infected Kidney Transplant Recipients

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2023
The reactivation of polyomavirus BK (BKPyV) contributes to increased morbidity and mortality rates of transplant patients, especially kidney transplant recipients (KTRs).
Nasrin Noshadi   +4 more
doaj   +1 more source

Expression of Death Receptor 3 (DR3) on Circulating CD4 Positive Lymphocytes on Patients with Vitiligo [PDF]

open access: yesBenha Journal of Applied Sciences, 2021
Vitiligo is the most common depigmenting skin disorder with an estimated prevalence of 0.5–2% of the population in both adults and children worldwide. Death receptor 3 is a typical member of TNFRSF which play a role in apoptotic signalling and differentiation.
G.S. Abd El-Aziz   +3 more
openaire   +1 more source

Causes of T lymphocyte activation in HIV-infected patients coinfected with hepatitis C virus [PDF]

open access: yesТерапевтический архив, 2016
Aim. To establish the causes of T lymphocyte activation in human immunodeficiency virus (HIV)-infected patients coinfected with hepatitis C (HCV) who are adherent to their antiretroviral therapy regimen and interferon untreated.
K V Shmagel   +4 more
doaj   +1 more source

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