Results 231 to 240 of about 463,708 (346)

CD4+ T-lymphocytes in human saccular intracranial aneurysm walls are associated with aneurysm rupture. [PDF]

J Neuropathol Exp Neurol
Firtser N, Netti E, Kekäläinen E, Lehti S, Kovanen PT, Niemelä M, Tulamo R.   +6 more
europepmc   +1 more source

CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity

Journal of Virology, 1987
M. Reddehase, W. Mutter, K. Münch, H. Bühring, U. Koszinowski   +4 more
semanticscholar   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Signaling Pathways of the Acquired Immune System and Myocardial Dysfunction in Chronic Kidney Disease-What Do We Know So Far? [PDF]

Biomolecules
Duni A, Georgopoulos C, Kitsos A, Markopoulos G, Dova L, Vartholomatos G, Dounousi E.   +6 more
europepmc   +1 more source

Lymphocyte-Dependent Inhibition of Growth of VirulentMycobacterium tuberculosisH37Rv Within Human Monocytes: Requirement for CD4+ T Cells in Purified Protein Derivative-Positive, But Not in Purified Protein Derivative-Negative Subjects [PDF]

, 1998
Richard F. Silver, Qing Li, W. Henry Boom, Jerrold J. Ellner   +3 more
openalex   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

Geospatial and Cell Density Analysis Using Multiplex Immunofluorescence Reveals an Important Role of Clustering Patterns of Immunosuppressive Macrophages in Survival Outcomes of Penile Squamous Cell Carcinoma. [PDF]

Cancers (Basel)
Fazili A, Gullapalli K, Roman Souza G, Hatoum F, Miller J, Kim Y, Whiting J, Johnson JS, Dhillon J, Nguygen J, Segura CM, Spiess PE, Chahoud J.   +12 more
europepmc   +1 more source

Proliferative potential of double positive CD4+/CD8+ T lymphocytes in coculture with tumor cells

, 2013
Bojin Florina, Cernescu Luminita, Cean Ada, Toma Marius, Lazarovicz Radu-Adrian, Marusciac Laura, Tanasie Gabriela, Panaitescu Carmen, Virgil Păunescu   +8 more
openalex   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Immuno-Hematological Profiles of HIV-Positive Patients Stratified by CD4⁺ T-Cell Counts: Toward Identifying a Surrogate Hematological Marker for Immune Suppression Severity. [PDF]

Diagnostics (Basel)
Arbaeen AF, Iqbal MS, Alsafi R, Al Masmoum H, Qadhi A, Alharbi W, Alharbi AM, Kedwa K, Albeshri MH, Alameer MS.   +9 more
europepmc   +1 more source