Results 1 to 10 of about 186,664 (282)

Comparative characteristic of lung cancer stem-like cells generated in vitro under different culture conditions [PDF]

The Ukrainian Biochemical Journal, 2021
Cancer stem cells (CSCs) play an important role in resistance to cancer treatment and recurrence developing. The aim of this study was to obtain cell culture of MOR line non-small cell lung cancer cells enriched in CSCs and to investigate its functional ...
O. V. Skachkova, O. I. Gorbach , M. V. Inomistova, L. V. Garmanchuk, N. M. Khranovska   +4 more
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FEATURES OF EXPRESSION OF CD133 AND CD44 MARKERS OF TUMOR STEM CELLS WITH METASTATIC AND NON-METASTATIC GASTRIC CANCER

Сибирский онкологический журнал, 2021
Background. Gastric cancer is the second leading cause of cancer-related death due to advanced disease. A special role in the pathogenesis and metastasis of the tumor is assigned to tumor stem cells (TSC ),  responsible for resistance to chemotherapy and
A. B. Sagakyants, O. I. Kit, E. P. Ulyanova, E. Yu. Zlatnik, I. A. Novikova, O. G. Shulgina, Yu. A. Gevorkyan, N. V. Soldatkina, N. S. Samoylenko, E. A. Dzhenkova, A. V. Shaposhnikov   +10 more
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Understanding Hyaluronan Receptor (CD44) Interaction, HA-CD44 Activated Potential Targets in Cancer Therapeutics [PDF]

Advanced Pharmaceutical Bulletin, 2021
Cancer is a complex mechanism involving a series of cellular events. The glycoproteins such as hyaluronan (HA) are a significant element of extracellular matrix (ECM), involve in the onset of cancer developmental process.
Gul-e-Saba Chaudhry, Abdah Akim, Muhammad Naveed Zafar, Naila Safdar, Yeong Yik Sung, Tengku Sifzizul Tengku Muhammad   +5 more
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CD44 related stemness maneuvers oral squamous cell carcinoma biology

Indian Journal of Pathology and Microbiology, 2022
Introduction: Despite the commendable advancements in oral squamous cell carcinoma (OSCC) diagnostics and therapeutics, it remains a considerable medical challenge. Recent evidence suggests that small populations of stem-like cancer cells are responsible
Ankita Tandon, Narendra N Singh, Nikita Gulati   +2 more
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Mutant Allele of CD44 (rs8193C>T) and Pum2 Regulatory Element as A Prognosis Factor of Prostate Neoplasms: A Case-Control and In Silico Studies [PDF]

Cell Journal, 2022
ObjectiveExpression of CD44 variant 6 (CD44v6) as a homing-associated cell adhesion molecule (HCAM), hasproved to change most cancer cells. Aim of the study is the effect of mutant allele of CD44 (rs8193C>T) and Pum2regulatory element as a prognosis ...
Mohammadkazem Heydari, Abasalt Hosseinzadeh Colagar, Emadoddin Moudi   +2 more
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The effect of hyaluronic acid on nucleus pulposus extracellular matrix production through hypoxia-inducible factor-1α transcriptional activation of CD44 under hypoxia [PDF]

European Cells & Materials, 2021
Intervertebral disc degeneration (IDD) is the leading cause of low-back pain. Implantation of hyaluronic acid (HA) is potentially a therapeutic strategy for IDD, but its pharmacological effects and mechanism under hypoxic conditions remain unclear.
F Zhang, X Liu, B Li, Z Li, S Grad, D Chen,, M Gao, S Liu   +7 more
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Activation of epidermal growth factor receptor/insulin-like growth factor 1 receptor-β-Catenin-CD44 pathway in periampullary cancer

Journal of Radiation and Cancer Research, 2020
Background: Periampullary cancer (PC) is a global medical burden. Less than 5% of patients experience an overall survival of 5 years or more. The study aims to analyze the importance of epidermal growth factor receptor (EGFR)/insulin-like growth factor 1
Biswabandhu Bankura, Suvendu Maji, Balarko Chakraborty, Neyaz Alam, Chinmay Kumar Panda   +4 more
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Directed movement toward, translocation along, penetration into and exit from vascular networks by breast cancer cells in 3D

Cell Adhesion & Migration, 2021
We developed a computer-assisted platform using laser scanning confocal microscopy to 3D reconstruct in real-time interactions between metastatic breast cancer cells and human umbilical vein endothelial cells (HUVECs).
Deborah J. Wessels, Claude Pujol, Nikash Pradhan, Daniel F. Lusche, Luis Gonzalez, Sydney E. Kelly, Elizabeth M. Martin, Edward R. Voss, Yang-Nim Park, Michael Dailey, Sonia L. Sugg, Sneha Phadke, Amani Bashir, David R. Soll   +13 more
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Nestin, CD44, Ki-67, GS and AQP4 expression in the brain neurogenic niches of deceased patients with liver cirrhosis of different degree

Patologìâ, 2023
The aim of the study. Immunohistochemical study of Nestin, CD44, Ki-67, GS, AQP4 expression in the subventricular zone of the lateral ventricle and hippocampus of deceased patients with liver cirrhosis depending on the age and Child–Pugh score ...
T. V. Shulyatnikova, V. O. Tumanskiy
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Human Papilloma Virus and Cancer Stem Cell markers in Oral Epithelial Dysplasia—An Immunohistochemical Study

Rambam Maimonides Medical Journal, 2021
Objectives: To study the correlation between the putative cancer stem cell (CSC) markers aldehyde dehydrogenase 1 (ALDH1), cluster of differentiation 44 (CD44), sex-determining region Y-box 2 (SOX2), and octamer-binding protein 4 (OCT4) and human ...
Prasanth Thankappan, Madhavan Nirmal Ramadoss, Tharmasahayam Isaac Joseph, Percy Ida Augustine, Isaacjoseph Bevin Shaga, Jashree Thilak   +5 more
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