Aldehyde dehydrogenase 1 and CD44 serve as prognostic markers in patients with breast cancer
Annals of Medical Science and Research, 2022 Background and Objective: Breast cancer is the second leading cause of cancer-related death in women globally, and its prevalence is rising quickly, particularly in low- and middle-income nations.
Ayan Pradhan, Diptendra Kumar Sarkar
doaj +1 more source
The small molecule ephrin receptor inhibitor, GLPG1790, Reduces renewal capabilities of cancer stem cells, showing anti-tumour efficacy on preclinical glioblastoma models [PDF]
, 2019 Therapies against glioblastoma (GBM) show a high percentage of failure associated with the survival of glioma stem cells (GSCs) that repopulate treated tumours.
Beirinckx, Filip +15 more
core +2 more sources
Proteomic analysis of CD44(+) and CD44(−) gastric cancer cells
Molecular and Cellular Biochemistry, 2014 CD44 is a cell surface protein and it is widely used as a cancer stem cell marker in various cancer types including gastric cancer. We conducted proteomic analysis in CD44(+) and CD44(-) gastric cancer cells to understand characteristics of CD44(+) and CD44(-) cells.
Dayeon, Yu +3 more
openaire +3 more sources
The glycoprotein GPNMB attenuates astrocyte inflammatory responses through the CD44 receptor
Journal of Neuroinflammation, 2018 Neuroinflammation is one of the hallmarks of neurodegenerative diseases, such as Parkinson’s disease (PD). Activation of glial cells, including microglia and astrocytes, is a characteristic of the inflammatory response.
Matthew L. Neal +4 more
semanticscholar +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Combining hyaluronic acid with chitosan enhances gene delivery [PDF]
, 2014 The low gene transfer efficiency of chitosan-DNA polyplexes is a consequence of their high stability and consequent slow DNA release. The incorporation of an anionic polymer is believed to loosen chitosan interactions with DNA and thus promote higher ...
Bitoque, Diogo +2 more
core +3 more sources
Advanced Functional Materials, EarlyView.A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee +8 more
wiley +1 more source
International Journal of Nanomedicine, 2023 Maisa Siddiq Abduh1,2 1Immune Responses in Different Diseases Research Group, Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia; 2Center of Excellence in Genomic Medicine ...
Abduh MS
doaj
Expression of MMP-14 and CD44 associated with proliferation of retinoblastoma cells
Medicine Science, 2019 Retinoblastoma is a the most common primary intraocular malignant tumor in childhood. The eexpressions of CD44 and MMP-14 and Their role in proliferation and migration cells appear crucial for retinoblastoma invasion.
Hendrian D. Soebagjo +4 more
doaj +1 more source
Malignant phyllodes tumors display mesenchymal stem cell features and aldehyde dehydrogenase/disialoganglioside identify their tumor stem cells. [PDF]
, 2014 IntroductionAlthough breast phyllodes tumors are rare, there is no effective therapy other than surgery. Little is known about their tumor biology.
Chou, Fen-Pi +9 more
core +3 more sources