Results 111 to 120 of about 139,619 (346)

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Organic AIE Nanoradiosensitizer Potentiates X‐Ray Triggered Continuous Reactive Oxygen Species Generation for Potent Cancer Radioimmunotherapy

Advanced Materials, EarlyView.
Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu, Minmin Zhang, Qinqin Huang, Song Gao, Sitong Chu, Qi Li, Wanyao Chen, Xinglong Zhang, Tianfu Zhang, Ben Zhong Tang, Shipeng Ning   +10 more
wiley   +1 more source

Assessment of Immuno-histochemical Expression of CD44 in Renal Tumors [PDF]

Al-Anbar Medical Journal
Background: Cluster of differentiation 44 (CD44) is the most commonly reported immune marker of the cancer stem cells in renal cell carcinoma.Objectives: To assess the frequency of CD44 expression in renal tumors, to assess the expression of CD44 in ...
Banan Mohammed, khalid Abdulfattah Khattab, Payman Salim   +2 more
doaj   +1 more source

Impact of structurally modifying hyaluronic acid on CD44 interaction.

Journal of materials chemistry. B, 2017
CD44 is a widely-distributed type I transmembrane glycoprotein that binds hyaluronic acid (HA) in most cell types, including primary tumor cells and cancer-initiating cells and has roles in cell migration, cell-cell, and cell-matrix adhesion.
D. Bhattacharya, D. Svechkarev, J. Souchek, T. K. Hill, M. Taylor, A. Natarajan, A. Mohs   +6 more
semanticscholar   +1 more source

Self‐Powered α Radionuclide Nanomedicine: Mitochondria‐Targeted Multimodal Energy Recycling for Amplified Radioimmunotherapy

Advanced Materials, EarlyView.
A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li, Chaochao Wang, Yelin Wu, Jiajia Zhang, Han Zhang, Shanshan Qin, Linglin Tang, Fei Yu   +7 more
wiley   +1 more source

CD44 is overexpressed and correlated with tumor progression in gallbladder cancer

Cancer Management and Research, 2018
Background Gallbladder cancer (GBC) is a highly lethal disease and the most common biliary tract malignant tumor with poor prognosis. Accumulating evidence indicates that cluster of differentiation 44 (CD44) is overexpressed in several malignancies and ...
Yuting He, Chen Xue, Yan Yu, Jianan Chen, Xiaolong Chen, Fang Ren, Z. Ren, G. Cui, R. Sun   +8 more
semanticscholar   +1 more source

CD44 and CD44 Variant 6 in Children with Acute Lymphoblastic Leukemia

Journal of Cancer Science & Therapy, 2015
Background and objectives: Acute lymphoblastic leukemia (ALL) is a malignant disorder of lymphoid progenitor cells. Many prognostic factors are important for therapeutic assignment. The cell adhesion molecule CD44 is involved in pathologic activities of tumour cells and hematological malignancies. CD44v6 is an important isoform of CD44 family. It plays
Abdel-Azeem M. El-Marazy, Hosny B Hamed, Ahmad A Omran, Esmat A. El-Sharkawy, Ayman G Ghobrial, Nagwa I Okaily, Waleed M Abd el Hameed   +6 more
openaire   +2 more sources

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

Advanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo, Alejandro Ramirez‐Romero, Diana Peixoto, Maria Vivero‐Lopez, Isabel Rodríguez‐Moldes, Angel Concheiro   +5 more
wiley   +1 more source

Comparison of E- cadherin and CD44 Marker Expression in Oral Lichen Planus, Oral Leukoplakia, and Oral Squamous Cell Carcinoma

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2022
Introduction: The role of E-cadherin and CD44 has been proven in the development and progression of cancerous and precancerous lesions. It seems that these two markers have a high ability to evaluate the premalignancy of lichen planus lesions and oral ...
Khadijeh Abdal, Samira Mostafazede, Nastaran Ghorbani, Mohammadreza Hafeziahmadi   +3 more
doaj  

The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation.

Journal of the National Cancer Institute, 2006
BACKGROUND If cancer arises and is maintained by a small population of cancer-initiating cells within every tumor, understanding how these cells react to cancer treatment will facilitate improvement of cancer treatment in the future.
Tiffany M. Phillips, W. McBride, F. Pajonk   +2 more
semanticscholar   +1 more source