Results 91 to 100 of about 145,654 (260)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

CD44 Expression on Epidermal Melanocytes [PDF]

, 1996
We examined CD44 expression on melanocytes to begin to understand what role CD44 might have in the normal behavior of melanocytes and to provide a basis for comparing CD44 expression in melanoma cells.
Haggerty, John G., Leonard M. Milstone, Zhou, Jing, Milstone, Leonard M., John G. Haggerty, Jing Zhou, Herbold, Kyle W., Kyle W. Herbold   +7 more
core   +1 more source

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source

Anticancer Analysis of CD44 Targeted Cyclosporine Loaded Thiolated Chitosan Nanoformulations for Sustained Release in Triple-Negative Breast Cancer [Retraction]

International Journal of Nanomedicine
Abduh MS. Int J Nanomedicine. 2023;18:5713–5732. We, the Editor and Publisher of the journal International Journal of Nanomedicine are retracting the published article.
Abduh MS
doaj  

Expression of CD44 and SALL4 in Leukoplakia and Oral Squamous Cell Carcinoma

Journal of Pharmacy and Bioallied Sciences
CD44 and SALL4 are markers of stemness and expressed in cancer stem cells (CSCs). Their deregulated expression was seen in various tumors and has been correlated with clinical severity.
Sahoo Pravudeva, Panda Abikshyeet, Dash Kailash Chandra, Bhuyian Lipsa, Raghuvanshi Malvika, Panda Baisali   +5 more
doaj   +1 more source

CD44 activation in mature B-cell malignancies by a novel recurrent IGH translocation

, 2010
Using inverse polymerase chain reaction, we identified CD44, located on chromosome 11p13, as a novel translocation partner of IGH in 9 of 114 cases of gastric, nongastric extranodal, follicular, and nodal diffuse large B-cell lymphoma (DLBCL).
So, CC, Chan, LC, William W. L. Choi, Wong, MLY, Li Chong Chan, Wan, TSK, Gopesh Srivastava, Srivastava, G, Florence Loong, Kai-Yau Wong, Lijun Shen, Chi-Chiu So, Kent-Man Chu, Anthony C. T. Liang, Guo, T, Ka-Kui Chan, Qian Tao, Tianhuan Guo, Chu, KM, Yun-Wen Chen, Chan, KK, Loong, F, Au, WY, Xiao-Tong Hu, Liang, ACT, Wong, KY, Thomas S. K. Wan, Kwong, YL, Shen, L, Choi, WWL, Wing-Yan Au, Lu, L, Yok-Lam Kwong, Michelle L. Y. Wong, Liang, RHS, Chen, YW, Raymond H. S. Liang, Chim, CS, Tao, Q, Liwei Lu, Chor-Sang Chim, Hu, XT   +41 more
core   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source

Expression of cancer stem cell marker CD44 and axillary lymph node metastasis in invasive ductal carcinoma of breast [PDF]

Al Ameen Journal of Medical Sciences
Introduction: CD44 is a cell surface transmembrane glycoprotein is a member of cell adhesion molecules responsible for mediating communication and adhesion between adjacent cells and extracellular matrix.
P. Anusha, B. Roshni Sumalini, S.K. Aamer Saleem, M. Pavani, Fakeha Begum   +4 more
doaj  

Protein expression of cancer stem cell markers ABCG2, podoplanin, and CD44 predicts early recurrence of oral squamous cell carcinoma: A study from Western India

Indian Journal of Pathology and Microbiology
Objectives: For oral squamous cell carcinoma (OSCC), we are likely at a juncture in clinical management, where the benefits of therapies are beginning to plateau.
Trupti I. Trivedi, Toral H. Mandaliya, Priti P. Trivedi   +2 more
doaj   +1 more source