Results 121 to 130 of about 136,526 (307)
Iraqi Journal of HematologyBACKGROUND: Multiple myeloma (MM) is a plasma cell disorder characterized by the infiltration of clonal plasma cells in the bone marrow and the detection of a monoclonal immunoglobulin in serum and/or urine.
May Ahmed Al-Ahmed +1 more
doaj +1 more source
LOF-CD44 and GOF-CD44 BMC are generated using retroviral transduction.
, 2018 CD44-/- BMC were isolated from the femurs and tibia of mice that had received 5-FU 4 days prior, and were then cultured with 3/6/SCF medium. CD44-/- BMC were transduced with GOF-CD44 or LOF-CD44 constructs, and CD44+/+ BMC were transduced with an empty ...
Meghan N. Dougan (5131013) +6 more
core +1 more source
Advanced Science, EarlyView.The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo +6 more
wiley +1 more source
The Role of CD44 in the Pathogenesis, Diagnosis, and Therapy of Gastric Cancer
Gut and Liver, 2011 CD44 is a transmembrane glycoprotein and surface receptor for hyaluronan that is involved in the response of cells to their microenvironment. CD44 splice variants play roles in carcinogenesis, differentiation, and lymph node metastasis and are predictive
doaj +1 more source
CancersThe glycoprotein CD44, with its many isoforms and variations in carbohydrate patterning, participates in a diverse set of cellular functions. This fact leads to the protein playing a role in many normal and pathologic cellular processes including a role in cancer progression and metastasis. These same facts make CD44 a strong therapeutic target in many
Jason Duex, Dan Theodorescu
openaire +2 more sources
CD44 is overexpressed and correlated with tumor progression in gallbladder cancer
, 2018 Yuting He,1,2,* Chen Xue,1,2,* Yan Yu,1,2 Jianan Chen,1,2 Xiaolong Chen,1,2 Fang Ren,2 Zhigang Ren,1,2 Guangying Cui,1,2 Ranran Sun1,2 1Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; 2Key
Sun RR +8 more
core
Chondroitin sulfate E fragments enhance CD44 cleavage and CD44-dependent motility in tumor cells.
, 2008 Contains fulltext : 69659.pdf (Publisher’s version ) (Closed access)During tumor cell invasion, certain extracellular matrix (ECM) components such as hyaluronan (HA) are degraded into small oligosaccharides, which are detected in ...
Dam, G.B. ten +10 more
core +1 more source
Advanced Science, EarlyView.In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin +13 more
wiley +1 more source
International Journal of Nanomedicine, 2023 Maisa Siddiq Abduh1,2 1Immune Responses in Different Diseases Research Group, Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia; 2Center of Excellence in Genomic Medicine ...
Abduh MS
doaj
A role of CD44 in atherosclerosis? Studies in mice and humans
, 2009 Atherosclerosis is an inflammatory disease that can lead to clinical complications such as myocardial infarction and stroke. Expressed in both vascular and inflammatory cells, adhesion molecule CD44 can be cleaved from the cell surface, and soluble CD44 ...
Sjöberg, Sara
core