Results 41 to 50 of about 139,619 (346)

High Expression of CD44 Predicts a Poor Prognosis in Glioblastomas

open access: yesCancer Management and Research, 2020
Daolin Si,1 Fei Yin,1 Jing Peng,1 Guangying Zhang2 1Department of Pediatric Neurology, Xiangya Hospital, Central South University, Changsha, Hunan Province 410008, People’s Republic of China; 2Department of Oncology, Xiangya Hospital, Central South
Si D, Yin F, Peng J, Zhang G
doaj  

CD133, but Not CD44, May Serve as a Novel Biomarker for Differential Diagnosis Between Basal Cell Carcinoma and Trichoblastomas

open access: yesClinical, Cosmetic and Investigational Dermatology, 2022
Yalan Bi,1 Xiaohua Shi,2 Dian Chen,1 Yi Zhao1 1Department of Dermatology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, People’s Republic of China; 2Department of Pathology, Peking Union Medical College ...
Bi Y, Shi X, Chen D, Zhao Y
doaj  

Expression of CD44 in Tumor Tissue and Serum of Small Cell Lung Cancer and Its Clinical Prognostic Significance

open access: yesChinese Journal of Lung Cancer, 2021
Background and objective Small cell lung cancer (SCLC) is a highly aggressive malignancy characterized by rapid growth, early metastasis and acquired therapeutic resistance, and the prognosis is extremely poor.
Ying WANG   +9 more
doaj   +1 more source

The Prognostic and Clinical Value of CD44 in Colorectal Cancer: A Meta-Analysis

open access: yesFrontiers in Oncology, 2019
Background: CD44 is widely used as a putative cancer stem cells (CSCs) marker for colorectal cancer (CRC). However, the prognostic role of CD44 in CRC remains controversial.

semanticscholar   +1 more source

Silencing of CD44 Expression in Prostate Cancer by Hypermethylation of the CD44 Promoter Region [PDF]

open access: yesLaboratory Investigation, 2000
Loss of the CD44 transmembrane glycoprotein in primary prostate cancer has been shown to be associated with unfavorable clinical behavior. Moreover, the majority of prostate cancer metastases lack expression of this molecule. The mechanism of CD44 silencing in prostate cancer was investigated using both patient material and in vivo-propagated human ...
M J Bussemakers   +4 more
openaire   +3 more sources

89Zr-Labeled Multifunctional Liposomes Conjugate Chitosan for PET-Trackable Triple-Negative Breast Cancer Stem Cell Targeted Therapy

open access: yesInternational Journal of Nanomedicine, 2020
Rui Yang,1,* Mudan Lu,2,* Lan Ming,1,* Yu Chen,1 Kai Cheng,1 Jie Zhou,1 Shiwen Jiang,1 Zhenyu Lin,3 Daozhen Chen1 1Research Institute for Reproductive Health and Genetic Diseases, Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing ...
Yang R   +8 more
doaj  

CD44: expanding the toolKIT [PDF]

open access: yesBlood, 2018
Expanding the universe of mast cell diseases beyond tyrosine kinase inhibitors, in this issue of Blood, Mueller et al find that the invasion receptor CD44 is both a biomarker of and potential therapeutic target for mast cell neoplasms ...
openaire   +3 more sources

Targeting Mechanics-Induced Fibroblast Activation through CD44-RhoA-YAP Pathway Ameliorates Crystalline Silica-Induced Silicosis

open access: yesTheranostics, 2019
Silicosis is pneumoconiosis of the lung, usually resulting from prolonged exposure to crystalline silica (CS). The hallmark of silicosis is excessive extracellular matrix (ECM) deposition produced by activated fibroblasts.
Siyi Li   +8 more
semanticscholar   +1 more source

CD44 in rheumatoid arthritis.

open access: yesArthritis research & therapy, 2003
CD44 is a multistructural cell-surface glycoprotein that can theoretically generate close to 800 isoforms by differential alternative splicing. At present, several dozen isoforms are known. The polymorphic nature of CD44 might explain its multifunctionality and its ability to interact with many cell-surface and extracellular ligands, the principal one ...
Shlomo Nedvetzki, David Naor
openaire   +3 more sources

The Serum Assay of Soluble CD44 Standard, CD44 Variant 5, and CD44 Variant 6 in Patients with Gastric Cancer [PDF]

open access: yesCancer Research and Treatment, 2003
Alternative splicing of CD44 and aberrant levels of soluble CD44 (sCD44) protein in the serum of cancer patients has been correlated to tumor progression and metastasis. The purpose of this study was to evaluate the concentrations, and the prognostic potential of sCD44s, sCD44v5 and sCD44v6, in patients with gastric cancer.The serum levels of sCD44s ...
Sung Hoon Noh, Chang Hak Yoo
openaire   +3 more sources

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