IGFBP-3 inhibits Wnt signaling in metastatic melanoma cells. [PDF]
, 2016 In previous works, we have shown that insulin-like growth factor-binding protein-3 (IGFBP-3), a tissue and circulating protein able to bind to IGFs, decreases drastically in the blood serum of patients with diffuse metastatic melanoma.
Londei, Paola +7 more
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LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells [PDF]
, 2010 The serine/threonine kinase LKB1 has a conserved role in Drosophila and nematodes to co-ordinate cell metabolism. During T lymphocyte development in the thymus, progenitors need to synchronize increased metabolism with the onset of proliferation and ...
Aifantis +50 more
core +5 more sources
GPER-induced signaling is essential for the survival of breast cancer stem cells. [PDF]
, 2020 G protein-coupled estrogen receptor-1 (GPER), a member of the G protein-coupled receptor (GPCR) superfamily, mediates estrogen-induced proliferation of normal and malignant breast epithelial cells.
Chan, Yu-Tzu +12 more
core +2 more sources
A perspective on challenges and opportunities in characterizing oral cancer stem cells
Frontiers in Bioscience-Landmark, 2020 Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a minority population of cells in a tumor that can self-renew and re-create the heterogeneity of the entire tumor. Cell lines, patient-derived tumor cells, and patient-derived xenografts
Subhashini Sadasivam +1 more
doaj +1 more source
Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease [PDF]
, 2008 © 2008 Zhu et al. This article is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).Maintaining tolerance of T cells to self-antigens
Kioussis, Dimitris +6 more
core +3 more sources
Nanoparticles for live cell microscopy: A surface-enhanced Raman scattering perspective. [PDF]
, 2017 Surface enhanced Raman scattering (SERS) nanoparticles are an attractive alternative to fluorescent probes for biological labeling because of their photostability and multiplexing capabilities.
Candas, Demet +7 more
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Front. Cell Dev. Biol., 2017 CD44 is a cell surface adhesion receptor that is highly expressed in many cancers and regulates metastasis via recruitment of CD44 to the cell surface.
Linda T. Senbanjo, M. Chellaiah
semanticscholar +1 more source
NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer. [PDF]
, 2017 N-myc and STAT interactor (NMI) has been proved to bind to different transcription factors to regulate a variety of signaling mechanisms including DNA damage, cell cycle and epithelial-mesenchymal transition. However, the role of NMI in the regulation of
Chen, Yiming +15 more
core +1 more source
CD44 (CD44 molecule (Indian blood group)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on CD44 (CD44 molecule (Indian blood group)), with data on DNA, on the protein encoded, and where the gene is implicated.
Sen, YP, Yip, GW
openaire +2 more sources
ECRG4 regulates neutrophil recruitment and CD44 expression during the inflammatory response to injury. [PDF]
, 2020 The complex molecular microenvironment of the wound bed regulates the duration and degree of inflammation in the wound repair process, while its dysregulation leads to impaired healing. Understanding factors controlling this response provides therapeutic
Baird, Andrew +5 more
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