Results 111 to 120 of about 3,844 (196)

Modulation of complement regulatory function and measles virus receptor function by the serine-threonine-rich domains of membrane cofactor protein (CD46) [PDF]

, 1994
K Iwata, Tsukasa Seya, Shigeharu Ueda, H Ariga, Shigeharu Nagasawa   +4 more
openalex   +1 more source

Expression of innate immune complement regulators on brain epithelial cells during human bacterial meningitis

Journal of Neuroinflammation, 2006
Background In meningitis, the cerebrospinal fluid contains high levels of innate immune molecules (e.g. complement) which are essential to ward off the infectious challenge and to promote the infiltration of phagocytes (neutrophils, monocytes).
Gasque Philippe, Neal Jim W, Canova Cecile   +2 more
doaj   +1 more source

Glycosyl-phosphatidylinositol-anchored and transmembrane forms of CD46 display similar measles virus receptor properties: virus binding, fusion, and replication; down-regulation by hemagglutinin; and virus uptake and endocytosis for antigen presentation by major histocompatibility complex class II molecules [PDF]

, 1994
G Varior-Krishnan, Marie-Claude Trescol-Biémont, Denise Naniche, Chantal Rabourdin‐Combe, Denis Gerlier   +4 more
openalex   +1 more source

Characterization of CD46 and β1 integrin dynamics during sperm acrosome reaction

Scientific Reports, 2016
The acrosome reaction (AR) is a process of membrane fusion and lytic enzyme release, which enables sperm to penetrate the egg surroundings. It is widely recognized that specific sperm proteins form an active network prior to fertilization and their ...
M. Frolikova, N. Sebková, L. Ded, K. Dvorakova-Hortova   +3 more
semanticscholar   +1 more source

Purification and characterization of the pig analogue of human membrane cofactor protein (CD46/MCP). [PDF]

, 1997
Carmen W. van den Berg, José Manuel Pérez de la Lastra, D. Llanes, B. Paul Morgan   +3 more
openalex   +1 more source

CD46 Null Packaging Cell Line Improves Measles Lentiviral Vector Production and Gene Delivery to Hematopoietic Stem and Progenitor Cells

Molecular Therapy: Methods & Clinical Development, 2019
Lentiviral vectors (LVs) pseudotyped with the measles virus hemagglutinin (H) and fusion (F) glycoproteins have been reported to more efficiently transduce hematopoietic stem and progenitor cells (HSPCs) compared with vesicular stomatitis virus ...
Stosh Ozog, Craig X. Chen, Elizabeth Simpson, Olivia Garijo, Nina D. Timberlake, Petra Minder, Els Verhoeyen, Bruce E. Torbett   +7 more
doaj  

Preclinical safety, pharmacokinetics, pharmacodynamics, and biodistribution studies with Ad35K++ protein: a novel rituximab cotherapeutic

Molecular Therapy: Methods & Clinical Development, 2016
Rituximab is a mouse/human chimeric monoclonal antibody targeted toward CD20. It is efficient as first-line therapy of CD20-positive B-cell malignancies. However, a large fraction of treated patients relapse with rituximab-resistant disease. So far, only
Maximilian Richter, Roma Yumul, Kamola Saydaminova, Hongjie Wang, Michael Gough, Audrey Baldessari, Roberto Cattaneo, Frank Lee, Chung-Huei Katherine Wang, Haishan Jang, Anne Astier, Ajay Gopal, Darrick Carter, André Lieber   +13 more
doaj   +1 more source

CD46 Protects against Chronic Obstructive Pulmonary Disease

PLoS ONE, 2011
Chronic obstructive pulmonary disease and emphysema develops in 15% of ex-smokers despite sustained quitting, while 10% are free of emphysema or severe lung obstruction. The cause of the incapacity of the immune system to clear the inflammation in the first group remains unclear.We searched genes that were protecting ex-smokers without emphysema, using
Grumelli, Sandra, Lu, Bao, Peterson, Leif, Maeno, Toshitaka, Gerard, Craig John   +4 more
openaire   +5 more sources

Periferal Lökositlerde CD35, CD46, CD55 ve CD59 Düzeyleri

Genel Tıp Dergisi, 2017
Giriş: Kompleman aktivasyonunun, hedef molekül dışında bulunan çevre dokulara zarar vermesini kompleman düzenleyici proteinler engeller. Özellikle CD35, CD46, CD55 ve CD59 hastalıklarla ilişkilendirilen kompleman düzenleyici proteinlerdir.
Aydan Karagül, Belkıs Koçtekin, Sevcan Uğur, Ayşegül Uğur Kurtoğlu   +3 more
doaj  

Soluble CD46 as a diagnostic marker of hepatic steatosis

eBioMedicine
Background The increasing prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) incurs substantial morbidity, mortality and healthcare costs. Detection and clinical intervention at early stages of disease improves prognosis; however, we are currently limited by a lack of reliable diagnostic tests for population screening and ...
Bitterer, Florian, Kupke, Paul, Adenugba, Akinbami, Evert, Katja, Glehr, Gunther, Riquelme, Paloma, Scheibert, Lena, Preverin, Giulia, Böhm, Christina, Hornung, Matthias, Schlitt, Hans J., Wenzel, Jürgen J., Geissler, Edward K., Safinia, Niloufar, Hutchinson, James A., Werner, Jens M.   +15 more
openaire   +3 more sources