Results 41 to 50 of about 17,628 (245)
Emerging Microbes and Infections, 2022 The genus Pestivirus within the family Flaviviridae comprises highly relevant animal pathogens such as bovine viral diarrhoea virus 1 and 2 (BVDV-1 and -2) classified into the two species Pestivirus A and Pestivirus B, respectively.
Elena Leveringhaus +4 more
doaj +1 more source
How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome [PDF]
, 2014 Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core +1 more source
Measles virus causes immunogenic cell death in human melanoma [PDF]
, 2011 Oncolytic viruses (OV) are promising treatments for cancer, with several currently undergoing testing in randomised clinical trials. Measles virus (MV) has not yet been tested in models of human melanoma.
Bond, Jacquelyn +14 more
core +1 more source
Viruses, 2023 This study examines an unexplored aspect of SARS-CoV-2 entry into host cells, which is widely understood to occur via the viral spike (S) protein’s interaction with human ACE2-associated proteins.
Pavel Vassiliev +5 more
doaj +1 more source
Viruses, 2020 Bovine viral diarrhea virus (BVDV) entry into a host cell is mediated by the interaction of the viral glycoprotein E2 with the cellular transmembrane CD46 receptor.
Kevin P. Szillat +4 more
doaj +1 more source
MicroRNAs regulating cluster of differentiation 46 (CD46) in cardioembolic and non-cardioembolic stroke. [PDF]
PLoS ONE, 2017 Ischemic stroke is a major cause of mortality and morbidity globally. Among the ischemic stroke subtypes, cardioembolic stroke is with poor functional outcome (Modified Rankin score ≥ 2).
Jun Rong Tan +6 more
doaj +1 more source
Using Cystine Knot Proteins as a Novel Approach to Retarget Oncolytic Measles Virus. [PDF]
, 2017 Modified measles virus (MV) has effective oncolytic activity preclinically and is currently being investigated in clinical trials for various types of cancer. We investigated the use of cystine knot proteins (CKPs) to direct MV activity.
Lal, Sangeet, Raffel, Corey
core +2 more sources
Cell-to-cell contact via measles virus haemagglutinin-CD46 interaction triggers CD46 downregulation
Journal of General Virology, 1995 CD46 downregulation by measles virus (MV) occurs after expression of virus haemagglutinin (H) protein on the surface of the infected cell and is a consequence of CD46-H interaction on the cell membrane. To assess whether CD46 downregulation also occurs after CD46-H interaction when these two molecules are expressed on distinct cells, we used human T ...
S, Krantic +2 more
openaire +2 more sources
Complements and Allergic Asthma
Pediatric Respirology and Critical Care Medicine, 2019 Regulatory T (Treg) cells play a central role in protecting against the development of allergic asthma and interleukin-10 (IL-10) producing T regulatory type 1 (Tr1) cells contribute to the regulation of asthma.
Ching-Yuang Lin, Yi-Giien Tsai
doaj +1 more source
Interaction of CD46 with measles virus: accessory role of CD46 short consensus repeat IV
Journal of General Virology, 2000 To define further the accessory role(s) of the CD46 (membrane cofactor protein) short consensus repeat (SCR) III and IV domains in the interaction of CD46 with measles virus (MV), chimeric proteins were generated by substituting domains from the structurally related protein decay accelerating factor (DAF, CD55): x3DAF (exchange of CD46 SCR III) and ...
Lanteri, Marc +5 more
openaire +3 more sources