Results 51 to 60 of about 18,453 (236)

Infection of polarized bovine respiratory epithelial cells by bovine viral diarrhea virus (BVDV)

open access: yesVirulence, 2021
Bovine viral diarrhea virus (BVDV) is affecting cattle populations all over the world causing acute disease, immunosuppressive effects, respiratory diseases, gastrointestinal, and reproductive failure in cattle.
Ang Su   +6 more
doaj   +1 more source

Different impact of bovine complement regulatory protein 46 (CD46bov) as a cellular receptor for members of the species Pestivirus H and Pestivirus G

open access: yesEmerging Microbes and Infections, 2022
The genus Pestivirus within the family Flaviviridae comprises highly relevant animal pathogens such as bovine viral diarrhoea virus 1 and 2 (BVDV-1 and -2) classified into the two species Pestivirus A and Pestivirus B, respectively.
Elena Leveringhaus   +4 more
doaj   +1 more source

Human Desmoglein-2 and Human CD46 Mediate Human Adenovirus Type 55 Infection, but Human Desmoglein-2 Plays the Major Roles

open access: yesJournal of Virology, 2020
Human adenovirus type 55 (HAdV55) has recently emerged as a highly virulent respiratory pathogen and has been linked to severe and even fatal pneumonia in immunocompetent adults.
Ying Feng   +16 more
semanticscholar   +1 more source

Complements and Allergic Asthma

open access: yesPediatric Respirology and Critical Care Medicine, 2019
Regulatory T (Treg) cells play a central role in protecting against the development of allergic asthma and interleukin-10 (IL-10) producing T regulatory type 1 (Tr1) cells contribute to the regulation of asthma.
Ching-Yuang Lin, Yi-Giien Tsai
doaj   +1 more source

Computational Analysis of CD46 Protein Interaction with SARS-CoV-2 Structural Proteins: Elucidating a Putative Viral Entry Mechanism into Human Cells

open access: yesViruses, 2023
This study examines an unexplored aspect of SARS-CoV-2 entry into host cells, which is widely understood to occur via the viral spike (S) protein’s interaction with human ACE2-associated proteins.
Pavel Vassiliev   +5 more
doaj   +1 more source

Molecular Imaging of Prostate Cancer Targeting CD46 Using ImmunoPET

open access: yesClinical Cancer Research, 2020
Purpose: We recently identified CD46 as a novel therapeutic target in prostate cancer. In this study, we developed a CD46-targeted PET radiopharmaceutical, [89Zr]DFO-YS5, and evaluated its performance for immunoPET imaging in murine prostate cancer ...
Sinan Wang   +24 more
semanticscholar   +1 more source

MicroRNAs regulating cluster of differentiation 46 (CD46) in cardioembolic and non-cardioembolic stroke. [PDF]

open access: yesPLoS ONE, 2017
Ischemic stroke is a major cause of mortality and morbidity globally. Among the ischemic stroke subtypes, cardioembolic stroke is with poor functional outcome (Modified Rankin score ≥ 2).
Jun Rong Tan   +6 more
doaj   +1 more source

Kinetic Redox Shotgun Proteomics Reveals Specific Lipopolysaccharide Effects on Intestinal Epithelial Cells, Mitigated by a Mn Superoxide Dismutase Mimic

open access: yesAngewandte Chemie, Volume 137, Issue 19, May 5, 2025.
Proteomics and redoxomics are efficient to quantify the effects of bacterial lipopolysaccharide in intestinal epithelial cells (HT29) at the proteome and at the Cys‐redoxome levels. Oxidative stress is the initial trigger of LPS leading to inflammation.
Martha Zoumpoulaki   +14 more
wiley   +2 more sources

Potential benefits and risks of clinical xenotransplantation [PDF]

open access: yes, 2012
The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core   +2 more sources

Functional Dissection of the Dominant Role of CD55 in Protecting Vesicular Stomatitis Virus against Complement-Mediated Neutralization

open access: yesViruses, 2021
The human complement system is an important part of the innate immune system. Its effector pathways largely mediate virus neutralization. Vesicular stomatitis virus (VSV) activates the classical pathway of the complement, leading to virus neutralization ...
Nisha Asok Kumar   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy