Results 51 to 60 of about 17,628 (245)
Wild-Type Measles Virus with the Hemagglutinin Protein of the Edmonston Vaccine Strain Retains Wild-Type Tropism in Macaques [PDF]
, 2012 journal ...
Ami Yasushi +11 more
core +1 more source
The changing role of cell culture in the generation of transgenic livestock [PDF]
, 1999 Transgenesis may allow the generation of farm animals with altered phenotype, animal models for research and animal bioreactors. Although such animals have been produced, the time and expense involved in generating transgenic livestock and then ...
Farini, E, Webster, J, Whitelaw, C B
core +1 more source
Frontiers in ImmunologyBackgroundCD46 has been revealed to be a key factor in malignant transformation and cancer treatment. However, the clinical significance of CD46 in cervical cancer remains unclear, and this study aimed to evaluate its role in cervical cancer diagnosis ...
Jun-Hui Yu +4 more
doaj +1 more source
Virology Journal, 2006 Human herpesvirus-6 (HHV-6) can infect blood cells and thereby may inhibit hematopoietic stem and progenitor cell expansion and differentiation. In this context, it has been discussed if early progenitor cells can be infected by HHV-6.
Thulke Stefanie +3 more
doaj +1 more source
PLoS Pathogens, 2021 The frequent overexpression of CD46 in malignant tumors has provided a basis to use vaccine-lineage measles virus (MeV) as an oncolytic virotherapy platform.
Miguel Ángel Muñoz-Alía +6 more
doaj +1 more source
Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies [PDF]
, 2016 Encouraging results from recent clinical trials are revitalizing the field of oncolytic virotherapies. Human adenovirus type 5 (HAdV-C5/Ad5) is a common vector for its ease of manipulation, high production titers and capacity to transduce multiple cell ...
Chester, John +4 more
core +1 more source
Viruses, 2021 The human complement system is an important part of the innate immune system. Its effector pathways largely mediate virus neutralization. Vesicular stomatitis virus (VSV) activates the classical pathway of the complement, leading to virus neutralization ...
Nisha Asok Kumar +6 more
doaj +1 more source
Cancer Science, EarlyView.Cancer‐specific antihuman podoplanin antibody chLpMab‐2f exerted antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity against pleural mesothelioma (PM) cell lines. Additionally, chLpMab‐2f inhibited tumor progression in mice with subcutaneously and intrathoracically transplanted human PM cells.
Aito Yoshida +15 more
wiley +1 more source
Autophagy Induction by the Pathogen Receptor CD46 [PDF]
Cell Host & Microbe, 2009 Autophagy is a highly regulated self-degradative mechanism required at a basal level for intracellular clearance and recycling of cytoplasmic contents. Upon intracellular pathogen invasion, autophagy can be induced as an innate immune mechanism to control infection.
Joubert, Pierre-Emmanuel +12 more
openaire +2 more sources
Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia. [PDF]
, 2019 IntroductionLevels of complement proteins (CPs) in plasma astrocyte-derived exosomes (ADEs) that are abnormal in Alzheimer's disease (AD) have not been assessed in mild cognitive impairment (MCI).MethodsParticipants (n = 20 per group) had either MCI ...
Elahi, Fanny M +4 more
core +2 more sources