Results 111 to 120 of about 29,411 (265)
Immunotherapeutic Blockade of CD47 Increases Virus Neutralization Antibodies
VaccinesBackground/Objectives: CD47 is a cell surface glycoprotein moderately expressed in healthy cells and upregulated in cancer and viral infected cells.
Lamin B. Cham +8 more
doaj +1 more source
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
Phytotherapy Research, EarlyView.This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source
Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine
Phytotherapy Research, EarlyView.By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao +11 more
wiley +1 more source
Cancer Medicine, 2019 Background Treatments based on the inhibition of pivotal signals of cancer stem cells (CSCs) are on a promising track. Recent studies have shown that targeting CSCs with broader immune‐based therapeutic methods, for example, the anti‐CD47 treatment, may ...
Jian‐Hua Wang +12 more
doaj +1 more source
Role of CD47 In Red Cell Apoptosis (Eryptosis) [PDF]
, 2019 CD47 is a 47-52 kDa membrane spanning glycoprotein, which has 5 known isoforms and is a member of the immunoglobulin superfamily (IgSF). It possesses a large extracellular N-terminal IgV like domain. CD47 acts as a ‘do not eat me’ signal and consequently
Halawani, Ibrahim Faisal
core
Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists
SmartBot, EarlyView.Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu +12 more
wiley +1 more source
Regulatory mechanisms of CD47 surface expression
, 2017 CD47 glycoprotein can be found on the surface of all healthy cells in our body. The interaction of CD47 with inhibitory receptor SIRPα on the macrophage leads to the inhibition of phagocytosis.
Jakubec, Martin
core
Advances in research on layered double hydroxides for biomedical applications
Smart Molecules, EarlyView.Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
Journal for ImmunoTherapy of CancerBackground Tumor-associated macrophages (TAMs) abundantly infiltrate tumors and possess potent antitumor capabilities. “Don‘t eat me” signals like CD47 allow tumors to evade macrophages and proliferate unchecked.
Chao Wang +13 more
doaj +1 more source