Results 251 to 260 of about 310,362 (291)

The 'target tissues' as orchestrators of autoimmune responses: the paradigm of Sjögren's syndrome. [PDF]

Clin Exp Immunol
Filika M, Katsiougiannis S.
europepmc   +1 more source

CD3ɛ Nanobody‐Engineered Extracellular Vesicles Driving In Vivo Generation of BiTE‐Secreting CAR‐Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity

Advanced Science, EarlyView.
HEK‐293T‐derived CD3ε Nb‐engineered EVs to generate dual‐targeting CAR‐T cells directly in vivo. These EVs selectively deliver CAR.BiTE transgenes into T cells and reprogramed to HLA‐G/PD‐L1‐targeting effector cells with enhanced memory and persistence.
Shi‐Wei Huang, Yu‐Chuan Lin, Chih‐Ming Pan, Yeh Chen, Ming‐You Shie, Cheng‐Yu Chen, Kai‐Wen Kan, Yi‐Wen Chen, Ming‐Chao Liu, Chung‐Chun Wu, Yu‐Ting Chiang, Huai‐Ping Ho, Chen‐Yu Lin, Pei‐Ying Lin, Yu‐Han Huang, Steffany Rusli, Wan‐Yu Mao, Pei‐Wen Huang, Sin‐Ting Wang, Wan‐Chen Tsai, Ya‐Hsu Chiu, Ting‐Hsun Lin, Wan‐Ling Chiang, Che‐Kai Chang, Zi‐Lun Lai, Mei‐Chih Chen, Shao‐Chih Chiu, Der‐Yang Cho   +27 more
wiley   +1 more source

CD4+ T Cells Mediate MHC-Deficient Tumor Rejection and Endothelial Cell Reprogramming. [PDF]

Cancer Immunol Res
Kim SI, Haerr ME, Al-Ghezi M, Chen C, Zhang Y, Phipps JL, Arora C, Gribbin KP, Kim G, Markosyan N, Xia Z, Vonderheide RH, Byrne KT.   +12 more
europepmc   +1 more source

Oral Celastrol Nanomedicine Targeting Intestinal Antigen‐Presenting Cells to Effectively Mitigate Autoimmune Uveitis via Gut‐Retina Axis

Advanced Science, EarlyView.
Oral nanoCEL exhibits effective intestinal targeting of antigen‐presenting cells and restores the Th17/Treg balance in lymph nodes and spleen, ultimately protecting the blood‐retinal barrier by inhibiting peripheral immune cell infiltration and suppressing retinal glial cell activation.
Jinrun Chen, Yuqin Wu, Bofei Xu, Jiabei Hou, Yijing Li, Yuhan Hu, Yutuo Zhu, Wenqiao Zhang, Shuqi Feng, Huanting Jin, Yuchen Cheng, Yuanyuan Jin, Jianhong Zhou, Xingyi Li   +13 more
wiley   +1 more source

LANA-specific CD4⁺ effector T cells accumulate at the site of KSHV infection in humanized mice. [PDF]

Nat Commun
Böni M, Peng S, Vanoaica D, Haal K, Nopper SL, Rieble L, Schmid S, Valencia-Camargo AD, Holler A, Stauss H, Münz C.   +10 more
europepmc   +1 more source

A Pool of Ferritin Nanoparticles Delivering Six Proteins of African Swine Fever Virus Induces Robust Humoral and Cellular Immune Responses in Pigs. [PDF]

Vaccines (Basel)
Lu Z, Zhong D, Song X, Lan J, Wang Y, Luo R, Chen S, Huang R, Qiu HJ, Li Y, Wang T, Sun Y.   +11 more
europepmc   +1 more source

Citrullinated peptides as drug candidates for rheumatoid arthritis. [PDF]

Front Immunol
Bustos AH, Brüner M, Kragstrup TW, Astakhova K.   +3 more
europepmc   +1 more source

IL-7: a potential next-generation adjuvant for immune cell therapies. [PDF]

Front Immunol
Hotchkiss RS, DiPersio JF, Yee C, Pachynski RK, Van Den Brink MRM.   +4 more
europepmc   +1 more source

Characterization of the SARS-CoV-2-Specific T Cell Responses in Rheumatoid Arthritis Subjects Vaccinated for COVID-19 Protection. [PDF]

Eur J Immunol
Song J, da Silva Antunes R, Seyede MA, Guma M, Sette A, Franco A.   +5 more
europepmc   +1 more source