Results 271 to 280 of about 221,142 (316)

Exploring Autologous Dendritic Cells for T Cell Modulation: A Step Towards Personalized Medicine in Leishmaniasis. [PDF]

Cells
Meunier M, Valério-Bolas A, Rodrigues A, Fróis-Martins F, Ferreira R, Cardoso I, Monteiro M, Palma-Marques J, Carvalheiro M, Nunes T, Antunes WT, Alexandre-Pires G, Pereira da Fonseca I, Santos-Gomes G.   +13 more
europepmc   +1 more source

Multiparameter antigen-specific immunoprofiling in subjects with negative IGRA and TST results with potential <i>M. tuberculosis</i> exposures. [PDF]

Front Cell Infect Microbiol
Pathakumari B, Gutierrez LE, Faisal SA, Sanchez PA, Daniel K, Van Keulen VP, Hilgart HR, Reddy MR, Theel E, Laniado-Laborin R, Clain JM, Peikert T, Bailey RC, Escalante P.   +13 more
europepmc   +1 more source

Therapeutic hepatitis B vaccine employing DNA prime - MVA boost scheme requires additional priming with recombinant HBsAg to elicit an adequate antibody response. [PDF]

Front Immunol
Kerth HA, Kächele M, Müller N, Singh S, Tulessin M, Sacherl J, Ates Öz E, Su J, Bester R, Miko S, Steiger K, Mogler C, Busch DH, Wettengel JM, Protzer U, Kosinska AD.   +15 more
europepmc   +1 more source

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Primary structure of the canine CD4 antigen

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1993
After PCR amplification two overlapping cDNA clones encoding the dog homologue of the human CD4 glycoprotein were identified. This internal fragment of the mature protein including the complete extracellular domains, consists of 1297 bp with a deduced amino acid sequence of 432 residues.
K F, Milde, G E, Conner, D H, Mintz, R, Alejandro   +3 more
openaire   +2 more sources

Characterization of Mouse CD4 TCR and Its Targeting Antigen

2022
The initial step of activation and differentiation of naïve CD4+ T cells is the TCR-antigenic stimulation. The specific antigen peptides (>11 residues) are presented by the class II MHC (MHC II) protein which expresses professional antigen-presenting cells (APCs).
Wenhua, Liang, Feng, Wang
openaire   +2 more sources

Modulation of CD4 by antigenic activation.

The Journal of Immunology, 1987
Abstract Cell surface expression of CD4, an invariant membrane glycoprotein, is characteristic of the MHC class II-restricted T cell helper/inducer subset. Although the specificity and restriction patterns of T lymphocytes are determined by the T cell receptor for antigen, CD4 might represent an additional "interaction" molecule that is ...
C M, Weyand, J, Goronzy, C G, Fathman
openaire   +2 more sources

Polymorphism of the CD4 and CD5 differentiation antigens in cattle

Veterinary Immunology and Immunopathology, 1991
Monoclonal antibodies (mAbs) specific for bovine CD4 and CD5 antigens have been found to identify polymorphic determinants on these molecules. In the case of CD5, mAb IL-A67 recognises one allotypic form of the antigen while four other CD5-specific mAbs in the workshop (CC17, CC29, BLT-1 and 8C11) recognise a second allotype.
W I, Morrison, C J, Howard, C A, Hinson
openaire   +2 more sources

Antigen Presentation by the CD4 Positive Monocyte Subset

Journal of Leukocyte Biology, 1990
Abstract Although CD4 antigen is expressed on monocytes (MØ), its functional role is uncharacterized. In this study, isolated human MØ were separated into CD4+ and CD4- MØ subsets and assessed for presentation of tetanus toxoid. The CD4- MØ subset had decreased antigen presenting cell (APC) capacity as well as increased PGE2 production ...
Szabo, Gyongyi, Miller-Graziano, Carol L., Kodys, Karen   +2 more
openaire   +3 more sources

In Vivo Activation of Antigen-Specific CD4 T Cells

Annual Review of Immunology, 2001
Physical detection of antigen-specific CD4 T cells has revealed features of the in vivo immune response that were not appreciated from in vitro studies. In vivo, antigen is initially presented to naïve CD4 T cells exclusively by dendritic cells within the T cell areas of secondary lymphoid tissues.
M K, Jenkins, A, Khoruts, E, Ingulli, D L, Mueller, S J, McSorley, R L, Reinhardt, A, Itano, K A, Pape   +7 more
openaire   +2 more sources