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Antigen presentation to naive CD4 T cells in the lymph node
Nature Immunology, 2003Although the presentation of peptide-major histocompatibility complex class II (pMHC class II) complexes to CD4 T cells has been studied extensively in vitro, knowledge of this process in vivo is limited. Unlike the in vitro situation, antigen presentation in vivo takes place within a complex microenvironment in which the movements of antigens, antigen-
Andrea A, Itano, Marc K, Jenkins
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The Generation and Antigen-Specificity of CD4+CD25+ Regulatory T Cells
Inflammation & Allergy-Drug Targets, 2006CD4+CD25+ regulatory T cells are essential components of the immune system. They help to maintain immune tolerance by exerting suppressive effects on cells of the adaptive and innate immune system. In the last few years there has been an abundance of papers addressing the suppressive effects of CD4+CD25+ regulatory T cells and their putative role in ...
Taams, L +3 more
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Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1999
A hybridoma secreting monoclonal antibody (mAb) specific to CD4 protein was generated. This monoclonal antibody, named MT4, was proved to be specific to CD4 protein as it reacted with CD4-DNA transfected COS cells, CD4+ cell lines and CD4+ lymphocytes.
W, Kasinrerk +2 more
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A hybridoma secreting monoclonal antibody (mAb) specific to CD4 protein was generated. This monoclonal antibody, named MT4, was proved to be specific to CD4 protein as it reacted with CD4-DNA transfected COS cells, CD4+ cell lines and CD4+ lymphocytes.
W, Kasinrerk +2 more
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Critical Care Management of Chimeric Antigen Receptor T-Cell Therapy Recipients
Ca-A Cancer Journal for Clinicians, 2022Sandrine Valadè +2 more
exaly
Antigen processing for presentation to CD4+ T cells.
The New biologist, 1992The immune system surveys the organism for the presence of foreign or abnormal structures. An important role in the immune response is assumed by T lymphocytes that recognize foreign antigen while tolerating self-proteins. T lymphocytes can recognize only peptide fragments that are presented to them by molecules of the major histocompatibility complex (
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Prostate-Specific Antigen: Current Status
Ca-A Cancer Journal for Clinicians, 1999Michael K Brawer, M K Brawer
exaly