Blastic plasmacytoid dendritic cell neoplasm [PDF]
Blastic plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with frequent cutaneous involvement and leukemic dissemination.
André Lencastre +5 more
doaj +1 more source
Virus and autoantigen-specific CD4+ T cells are key effectors in a SCID mouse model of EBV-associated post-transplant lymphoproliferative disorders. [PDF]
Polyclonal Epstein-Barr virus (EBV)-infected B cell line (lymphoblastoid cell lines; LCL)-stimulated T-cell preparations have been successfully used to treat EBV-positive post-transplant lymphoproliferative disorders (PTLD) in transplant recipients, but ...
Stefanie Linnerbauer +5 more
doaj +1 more source
Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses [PDF]
Alum is used as a vaccine adjuvant and induces T<sub>h</sub>2 responses and T<sub>h</sub>2-driven antibody isotype production against co-injected antigens.
White, Janice +11 more
core +1 more source
Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. [PDF]
BACKGROUND: Tuberculosis (TB) remains a global health threat with 9 million new cases and 1.4 million deaths per year. In order to develop a protective vaccine, we need to define the antigens expressed by Mycobacterium tuberculosis (Mtb), which are ...
Kaufmann, S.H.E. +157 more
core +1 more source
Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease [PDF]
© 2008 Zhu et al. This article is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).Maintaining tolerance of T cells to self-antigens
Suling Li +14 more
core +1 more source
Differential CD4+ and CD8+ T cell recognition of mycobacterial antigens in pediatric versus adult TB [PDF]
Is the capacity of Mtb-specific CD4+ and CD8+ T cells to produce three key Th-1 cytokines compromised among Ugandan children with TB as compared to Ugandan adults with TB?
Morrow, Erin
core +1 more source
Background The IFN-γ ELISPOT assay has been used to examine the T-cell repertoire for many disease states in humans but, as yet, not genital herpes. Using overlapping synthetic peptide libraries, an IFN-γ ELISPOT assay was established that could measure ...
Payne Lendon G +2 more
doaj +1 more source
New perspective on dextran sodium sulfate colitis: antigen-specific T cell development during intestinal inflammation. [PDF]
CD4+ T cell responses against oral antigens can develop in inflammatory bowel disease (IBD) patients, which may modulate disease. Dextran sodium sulfate (DSS) colitis is commonly used to study IBD, however, it is not considered the best model in which to
Mary E Morgan +8 more
doaj +1 more source
The effects of human immunodeficiency virus (HIV) on the immune response in patients with cutaneous leishmaniasis have not yet been fully delineated.
Luana Leandro Gois +5 more
doaj +1 more source
Investigations of mycobacteria-specific memoryy/effector T cell responses in HIV infected children receiving antiretroviral therapy [PDF]
Includes abstract.Includes bibliographical references (leaves 170-210).Human immunodeficiency virus (HIV) infected children are at greater risk of developing tuberculosis disease, and might benefit from vaccination with novel TB vaccines. However, little
Tena-Coki, Nontobeko Gwendoline
core +1 more source

