Results 31 to 40 of about 306,421 (309)
mSphere, 2019 Microneme (MIC) proteins play important roles in the recognition, adhesion, and invasion of host cells by Toxoplasma gondii. Previous studies have shown that MIC proteins are highly immunogenic in the mouse and recognized by human serum antibodies.
Iti Saraav +3 more
doaj +1 more source
Sézary Syndrome with CD4/CD8 Double-Negative Neoplastic T Cells in Peripheral Blood
Case Reports in Hematology, 2021 Sézary syndrome is a rare leukemic type of cutaneous T-cell lymphoma characterized by the presence of neoplastic T cells with cerebriform nuclei (Sézary cells) in the skin, lymph nodes, and peripheral blood.
Yuki Kageyama +6 more
doaj +1 more source
Heterogeneity of autoreactive T cell clones specific for the E2 component of the pyruvate dehydrogenase complex in primary biliary cirrhosis. [PDF]
, 1995 The extraordinary specificity of bile duct destruction in primary biliary cirrhosis (PBC) and the presence of T cell infiltrates in the portal tracts have suggested that biliary epithelial cells are the targets of an autoimmune response.
Ansari, A +10 more
core +2 more sources
Modelling bispecific monoclonal antibody interaction with two cell membrane targets indicates the importance of surface diffusion [PDF]
, 2016 We have developed a mathematical framework for describing a bispecific monoclonal antibody interaction with two independent membrane-bound targets that are expressed on the same cell surface.
Argungu, Maryam +8 more
core +1 more source
Pathogen-reactive T helper cell analysis in the pig [PDF]
, 2017 There is growing interest in studying host-pathogen interactions in human-relevant large animal models such as the pig. Despite the progress in developing immunological reagents for porcine T cell research, there is an urgent need to directly assess ...
Agnone +63 more
core +7 more sources
PLoS ONE, 2007 BackgroundEpstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive ...
Dinesh Adhikary +8 more
doaj +1 more source
Journal for ImmunoTherapy of Cancer, 2023 Background Antitumor mechanisms of CD4+ T cells remain crudely defined, and means to effectively harness CD4+ T-cell help for cancer immunotherapy are lacking. Pre-existing memory CD4+ T cells hold potential to be leveraged for this purpose.
Daniel Landi +10 more
doaj +1 more source
Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development. [PDF]
, 2012 Brucella spp., are Gram negative bacteria that cause disease by growing within monocyte/macrophage lineage cells. Clinical manifestations of brucellosis are immune mediated, not due to bacterial virulence factors.
Alessandro eSette +8 more
core +1 more source
Mediators of Inflammation, 2014 The nature of effector cells and the potential immunogenicity of Leishmania major excreted/secreted proteins (LmES) were evaluated using peripheral blood mononuclear cells (PBMCs) from healed zoonotic cutaneous leishmaniasis individuals (HZCL) and ...
Ikbel Naouar +7 more
doaj +1 more source
Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]
, 2018 CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar +7 more
core +6 more sources