Results 31 to 40 of about 665,801 (300)

Blastic plasmacytoid dendritic cell neoplasm [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2013
Blastic plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with frequent cutaneous involvement and leukemic dissemination.
André Lencastre   +5 more
doaj   +1 more source

Virus and autoantigen-specific CD4+ T cells are key effectors in a SCID mouse model of EBV-associated post-transplant lymphoproliferative disorders. [PDF]

open access: yesPLoS Pathogens, 2014
Polyclonal Epstein-Barr virus (EBV)-infected B cell line (lymphoblastoid cell lines; LCL)-stimulated T-cell preparations have been successfully used to treat EBV-positive post-transplant lymphoproliferative disorders (PTLD) in transplant recipients, but ...
Stefanie Linnerbauer   +5 more
doaj   +1 more source

Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses [PDF]

open access: yes, 2008
Alum is used as a vaccine adjuvant and induces T<sub>h</sub>2 responses and T<sub>h</sub>2-driven antibody isotype production against co-injected antigens.
White, Janice   +11 more
core   +1 more source

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa. [PDF]

open access: yes, 2013
BACKGROUND: Tuberculosis (TB) remains a global health threat with 9 million new cases and 1.4 million deaths per year. In order to develop a protective vaccine, we need to define the antigens expressed by Mycobacterium tuberculosis (Mtb), which are ...
Kaufmann, S.H.E.   +157 more
core   +1 more source

Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease [PDF]

open access: yes, 2008
© 2008 Zhu et al. This article is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).Maintaining tolerance of T cells to self-antigens
Suling Li   +14 more
core   +1 more source

Differential CD4+ and CD8+ T cell recognition of mycobacterial antigens in pediatric versus adult TB [PDF]

open access: yes, 2023
Is the capacity of Mtb-specific CD4+ and CD8+ T cells to produce three key Th-1 cytokines compromised among Ugandan children with TB as compared to Ugandan adults with TB?
Morrow, Erin
core   +1 more source

Characterization of the IFN-γ T-cell responses to immediate early antigens in humans with genital herpes

open access: yesVirology Journal, 2006
Background The IFN-γ ELISPOT assay has been used to examine the T-cell repertoire for many disease states in humans but, as yet, not genital herpes. Using overlapping synthetic peptide libraries, an IFN-γ ELISPOT assay was established that could measure ...
Payne Lendon G   +2 more
doaj   +1 more source

New perspective on dextran sodium sulfate colitis: antigen-specific T cell development during intestinal inflammation. [PDF]

open access: yesPLoS ONE, 2013
CD4+ T cell responses against oral antigens can develop in inflammatory bowel disease (IBD) patients, which may modulate disease. Dextran sodium sulfate (DSS) colitis is commonly used to study IBD, however, it is not considered the best model in which to
Mary E Morgan   +8 more
doaj   +1 more source

Decreased memory T-cell response and function in human immunodeficiency virus-infected patients with tegumentary leishmaniasis

open access: yesMemorias do Instituto Oswaldo Cruz, 2014
The effects of human immunodeficiency virus (HIV) on the immune response in patients with cutaneous leishmaniasis have not yet been fully delineated.
Luana Leandro Gois   +5 more
doaj   +1 more source

Investigations of mycobacteria-specific memoryy/effector T cell responses in HIV infected children receiving antiretroviral therapy [PDF]

open access: yes, 2011
Includes abstract.Includes bibliographical references (leaves 170-210).Human immunodeficiency virus (HIV) infected children are at greater risk of developing tuberculosis disease, and might benefit from vaccination with novel TB vaccines. However, little
Tena-Coki, Nontobeko Gwendoline
core   +1 more source

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