Results 41 to 50 of about 221,142 (316)
Mediators of Inflammation, 2014 The nature of effector cells and the potential immunogenicity of Leishmania major excreted/secreted proteins (LmES) were evaluated using peripheral blood mononuclear cells (PBMCs) from healed zoonotic cutaneous leishmaniasis individuals (HZCL) and ...
Ikbel Naouar +7 more
doaj +1 more source
Identification of DRG-1 As a Melanoma-Associated Antigen Recognized by CD4+ Th1 Cells. [PDF]
PLoS ONE, 2015 Immunotherapy has emerged as a promising strategy for the treatment of metastatic melanoma. Clinical studies have demonstrated the feasibility of cancer immunotherapy using tumor antigens recognized by CD8(+) T cells.
Yukiko Kiniwa +6 more
doaj +1 more source
Analysis of monoclonal antibodies reactive with the porcine CD4 antigen
Veterinary Immunology and Immunopathology, 1994 As result of the First International Swine CD Workshop, four monoclonal antibodies (mAb) (#002, 054, 118, and 127) clustered closely to the internal standard anti-porcine CD4 mAb, 74-12-4. To further characterize the relationship between these mAb, they were used in flow cytometry to inhibit binding of 74-12-4 to porcine lymphocytes. mAb #002 (74-12-4)
Pescovitz, M. D. +15 more
openaire +4 more sources
Species heterogeneity in macrophage expression of the CD4 antigen. [PDF]
The Journal of experimental medicine, 1987 The CD4 antigen is expressed on T cells of all mammalian species examined and appears to play an important role in the response of T cells to antigen. In humans, the molecule acts as a receptor for the AIDS virus. Previous studies have demonstrated that M phi in the rat and human also express the CD4 antigen, which is indistinguishable from that on T ...
P R, Crocker +4 more
openaire +2 more sources
, 2005 CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Gotto, J +19 more
core +1 more source
Lack of immune responses to Mycobacterium tuberculosis DosR regulon proteins following Mycobacterium bovis BCG vaccination. [PDF]
, 2007 Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis (TB), despite its variable protective efficacy. Relatively little is known about the immune response profiles following BCG vaccination in relation to protection against TB. Here we
Klein, Michèl R +12 more
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Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides
Journal of Immunology Research, 2015 We retrospectively analyzed the clinicopathological correlation and prognostic value of cell surface antigens expressed by peripheral blood mononuclear cells in patients with mycosis fungoides (MF). 121 consecutive MF patients were included in this study.
Serkan Yazıcı +9 more
doaj +1 more source
Enhancement of tumour-specific immune responses in vivo by 'MHC loading-enhancer' (MLE). [PDF]
PLoS ONE, 2009 BACKGROUND:Class II MHC molecules (MHC II) are cell surface receptors displaying short protein fragments for the surveillance by CD4+ T cells. Antigens therefore have to be loaded onto this receptor in order to induce productive immune responses.
Katharina Dickhaut +7 more
doaj +1 more source
, 2008 Background - Immunity to malaria develops naturally in endemic regions, but the protective immune mechanisms are poorly understood. Many vaccination strategies aim to induce T cells against diverse pre-erythrocytic antigens, but correlates of protection ...
Magdalena Plebanski +37 more
core +1 more source
Adjuvance of influenza virosomes in CTL induction in vitro [PDF]
, 2005 The induction of cytotoxic T lymphocyte (CTL) responses is of high relevance in immunological defense against intracellular pathogens and tumor cells.
Schumacher, Reto
core +1 more source