Results 211 to 220 of about 141,166 (348)

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

A diagnostic prediction model was established based on the clinical characteristics of multicenter children with Kawasaki disease in Xinjiang. [PDF]

Front Cardiovasc Med
Niu M, Lin Z, Zhang F, Chen Y, Zhang L, Pan J, Chen C, Yang H, Mao L, Chen L, Guan H, Sun Y, Zhang Z, Lv J.   +13 more
europepmc   +1 more source

CD4 Lymphocyte Percentage Predicts Disease Progression in HIV‐Infected Patients Initiating Highly Active Antiretroviral Therapy with CD4 Lymphocyte Counts >350 Lymphocytes/mm³ [PDF]

, 2005
Todd Hulgan, Stephen Raffanti, Asghar Kheshti, Robert B. Blackwell, Peter F. Rebeiro, Gema Barkanic, Brandon Ritz, Timothy R. Sterling   +7 more
openalex   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

Discrimination exposure and lymphocyte differentiation: Results from the health and retirement study. [PDF]

Brain Behav Immun Health
Kranz EO, Bather JR, Zhang X, Chang VW, Cole SW, Cuevas AG.   +5 more
europepmc   +1 more source

TOTAL LYMPHOCYTE COUNT AS AN ALTERNATIVE TO CD4 COUNT IN MANAGMENT OF HIV/AIDS PATIENTS

M K Javaid, Masuma Ghazanfar, Fatima Rehman   +2 more
openalex   +2 more sources

Value of the use of absolute lymphocyte as surrogate for CD4 count in resource poor situations

, 2014
OluwafemiJohnson Adegbamigbe, JamesOlabanji Adewuyi, PhilipO Olatunji   +2 more
openalex   +1 more source

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Correction: Hodgkin lymphoma: the role of EBV plasma viral load testing in an HIV-endemic setting. [PDF]

Clin Exp Med
Opie J, Mohamed Z, Chetty D, Bailey J, Brown K, Verburgh E, Hardie D.   +6 more
europepmc   +1 more source

T activation marker evaluation in ARC patients treated with AZT. Comparison with CD4+ lymphocyte count in non-progressors and progressors towards AIDS [PDF]

, 1990
M. Levacher, S TALLET, Marie‐Christine Dazza, E Dournon, B Rouveix, J J Pocidalo   +5 more
openalex   +1 more source