Evaluating Pediatric Reference Ranges for Extended Immunophenotyping from a Finnish Cohort against Published References. [PDF]
Äärimaa E +13 more
europepmc +1 more source
A Murine Bispecific Antibody Efficiently Redirects T Cells Against Calr Mutated Stem Cells In Vivo
ABSTRACT Calreticulin (CALR) mutations are prevalent in 20%–30% of patients with BCR::ABL1‐negative myeloproliferative neoplasms (MPN). Mutant calreticulin (mutCALR), presented by the thrombopoietin receptor (MPL, also known as TPOR or CD110) on the surface of the disease‐initiating MPN progenitors, represents an ideal target for curative ...
Shengen Xiong +5 more
wiley +1 more source
Higher soluble CD8 correlates with poor prognosis in hospitalized pulmonary infection patients. [PDF]
Li Y +6 more
europepmc +1 more source
[Total lymphocyte-count as a substitute for CD4 positive lymphocyte determination].
G, Rey, G, Tate, A, Malbrán
openaire +1 more source
New approaches to treating chronic obstructive pulmonary disease with Colla corii asini
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang +5 more
wiley +1 more source
Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity
A covalent allosteric inhibitor M029 was discovered for SHP1, a novel target for immunotherapy. M029 binds to a cryptic Cys remote from the active site, exhibits robust target engagement, and blocks tumor progression by stimulating antitumor immune response.
Zihan Qu +16 more
wiley +2 more sources
CD4<sup>+</sup> T cells stratification unveils a dynamic pathogen landscape in severe pneumonia: a targeted next-generation sequencing-based cohort study. [PDF]
Wang S +5 more
europepmc +1 more source
Correlation analysis on total lymphocyte count and CD4 count of HIV-infected patients
F. R. Liu +6 more
openaire +1 more source

