Microfluidic Assays for CD4 T Lymphocyte Counting: A Review
CD4 T lymphocytes play a key role in initiating the adaptive immune response, releasing cytokines that mediate numerous signal transduction pathways across the immune system. Therefore, CD4 T cell counts are widely used as an indicator of overall immunological health. HIV, one of the leading causes of death in the developing world, specifically targets
Zhuolun Meng+7 more
openaire +2 more sources
HIV dynamics and natural history studies: Joint modeling with doubly interval-censored event time and infrequent longitudinal data [PDF]
Hepatitis C virus (HCV) coinfection has become one of the most challenging clinical situations to manage in HIV-infected patients. Recently the effect of HCV coinfection on HIV dynamics following initiation of highly active antiretroviral therapy (HAART) has drawn considerable attention.
arxiv +1 more source
Correlation of Total Lymphocyte Count with CD4 Count in HIV/AIDS Patients
HIV infection is a chronic infection of the immune system with a target of CD4 cells. Total lymphocyte count (TLC) can be done in resource-limited areas and are able to be used as a substitute to CD4 count. An increase in CD8 count can disturb the correlation between CD4 and TLC especially during the late clinical stage.Objective of this research is to
Ronald Jonathan+2 more
openaire +3 more sources
Age-related changes in blood lymphocyte subsets of south Indian children [PDF]
Background. Enumeration of lymphocyte subsets has been widely used for the diagnosis and monitoring of several haematological and immunological disorders.
Arunkumar, N+4 more
core
Immunological Changes after Cancer Treatment and Participation in an Exercise Program [PDF]
Purpose: The purpose of this investigation was to evaluate the impact of undertaking peripheral blood stem cell transplantation (PBST) on T-cell number and function, and to determine the role of a mixed type, moderate intensity exercise program in ...
Andrykowski+27 more
core +2 more sources
Effect of dimethyl fumarate on lymphocyte subsets in patients with relapsing multiple sclerosis. [PDF]
Background: In patients treated with dimethyl fumarate, absolute lymphocyte count decline typically occurs during the first year and then plateaus; early drops have been associated with the development of severe prolonged lymphopenia.
Bandari, Daniel+15 more
core +1 more source
Predictors of CD4+ lymphocyte count among HIV-Seropositive and HIV-Seronegative pregnant women in Dar Es Salaam, Tanzania [PDF]
Objective: To determine the predictors of CD4+ lymphocyte count among pregnant women in Dar es Salaam, Tanzania.Methods: Between 04/1995 and 03/1997, HIV-seropositive (n=1,027) and HIV- seronegative (n=280) pregnant women were interviewed to obtain socio-
Fawzi, WW+5 more
core +2 more sources
Daily Preventive Zinc Supplementation Decreases Lymphocyte and Eosinophil Concentrations in Rural Laotian Children from Communities with a High Prevalence of Zinc Deficiency: Results of a Randomized Controlled Trial. [PDF]
BACKGROUND:Zinc deficiency impairs immune function and is common among children in South-East Asia. OBJECTIVES:The effect of zinc supplementation on immune function in young Laotian children was investigated.
Andreini+54 more
core +2 more sources
Comparison of absolute neutrophil to CD4 lymphocyte values as a marker of immunosuppression in cancer patients on cytotoxic chemotherapy [PDF]
Background: The absolute neutrophil count (ANC) is currently used to assess immune status of patients on cytotoxic therapy. The CD4 lymphocytes have also been shown to be of importance in protection against opportunistic infections.
Chukwura, A+4 more
core +2 more sources
Correlation analysis on total lymphocyte count and CD4 count of HIV-infected patients
To determine the relationship between CD4 count and other blood indices and to explore the prediction of total lymphocyte count (TLC) for CD4 count in HIV-infected patients.Cross-sectional study was performed for the prediction of TLC and other indices for CD4 count, and historical cohort study was performed for the TLC changes as a surrogate for CD4 ...
P. L. Zhou+6 more
openaire +3 more sources