Results 251 to 260 of about 14,389,011 (296)
CD4⁺ T cells confer transplantable rejuvenation via Rivers of telomeres
Lanna A, Valvo S, Dustin ML, Rinaldi F.
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Nature Cancer, 2023
Cancer immunology and immunotherapy are driving forces of research and development in oncology, mostly focusing on CD8+ T cells and the tumor microenvironment. Recent progress highlights the importance of CD4+ T cells, corresponding to the long-known fact that CD4+ T cells are central players and coordinators of innate and antigen-specific immune ...
Daniel E. Speiser +3 more
openaire +2 more sources
Cancer immunology and immunotherapy are driving forces of research and development in oncology, mostly focusing on CD8+ T cells and the tumor microenvironment. Recent progress highlights the importance of CD4+ T cells, corresponding to the long-known fact that CD4+ T cells are central players and coordinators of innate and antigen-specific immune ...
Daniel E. Speiser +3 more
openaire +2 more sources
Nature Immunology, 2023
Specialized subpopulations of CD4+ T cells survey major histocompatibility complex class II-peptide complexes to control phagosomal infections, help B cells, regulate tissue homeostasis and repair or perform immune regulation. Memory CD4+ T cells are positioned throughout the body and not only protect the tissues from reinfection and cancer, but also ...
Marco Künzli, David Masopust
openaire +2 more sources
Specialized subpopulations of CD4+ T cells survey major histocompatibility complex class II-peptide complexes to control phagosomal infections, help B cells, regulate tissue homeostasis and repair or perform immune regulation. Memory CD4+ T cells are positioned throughout the body and not only protect the tissues from reinfection and cancer, but also ...
Marco Künzli, David Masopust
openaire +2 more sources
CD4+ T cells in antitumor immunity
Trends in CancerAdvances in cancer immunotherapy have transformed cancer care and realized unprecedented responses in many patients. The growing arsenal of novel therapeutics - including immune checkpoint inhibition (ICI), adoptive T cell therapies (ACTs), and cancer vaccines - reflects the success of cancer immunotherapy.
Lawrence Fong, Elena Montauti
exaly +3 more sources
Seminars in Immunology, 2004
CD4 T-cell memory is in some ways more enigmatic than CD8 T-cell memory. This is mostly due to the fact that CD4 T cells tend to expand far less in response to antigenic stimuli, thereby thwarting attempts at their detection during the course of an immune response.
Brigitta, Stockinger +2 more
openaire +2 more sources
CD4 T-cell memory is in some ways more enigmatic than CD8 T-cell memory. This is mostly due to the fact that CD4 T cells tend to expand far less in response to antigenic stimuli, thereby thwarting attempts at their detection during the course of an immune response.
Brigitta, Stockinger +2 more
openaire +2 more sources
Current Opinion in Rheumatology, 2007
Many autoimmune rheumatic autoimmune disorders predominantly affect women. Sex hormones, in particular estrogen, can influence CD4 T-helper development and function. We highlight recent studies that begin to provide insights into the mechanisms by which estrogen modulates CD4 T-cell development and function, and thus potentially contribute to disease ...
openaire +2 more sources
Many autoimmune rheumatic autoimmune disorders predominantly affect women. Sex hormones, in particular estrogen, can influence CD4 T-helper development and function. We highlight recent studies that begin to provide insights into the mechanisms by which estrogen modulates CD4 T-cell development and function, and thus potentially contribute to disease ...
openaire +2 more sources
NeoReviews, 2013
The immune system has evolved to fend off challenges from a wide array of pathogens while maintaining tolerance to self-antigens and benign environmental antigens. CD4 helper T cells are critical in regulating these processes with different subsets of CD4 T cells responsible for regulating different facets of the immune system.
Emily G. Blosser, David A. Randolph
openaire +1 more source
The immune system has evolved to fend off challenges from a wide array of pathogens while maintaining tolerance to self-antigens and benign environmental antigens. CD4 helper T cells are critical in regulating these processes with different subsets of CD4 T cells responsible for regulating different facets of the immune system.
Emily G. Blosser, David A. Randolph
openaire +1 more source
Current Opinion in Immunology, 2008
The induction of adaptive immune responses critically depends on helper signals provided by CD4(+) T cells. These signals not only license antigen presenting cells (APC) to activate naïve CD8(+) T cells leading to the formation of vast numbers of cytotoxic T lymphocytes but also support the differentiation of B cells into immunoglobulin-secreting ...
Pablo J, van de Berg +3 more
openaire +2 more sources
The induction of adaptive immune responses critically depends on helper signals provided by CD4(+) T cells. These signals not only license antigen presenting cells (APC) to activate naïve CD8(+) T cells leading to the formation of vast numbers of cytotoxic T lymphocytes but also support the differentiation of B cells into immunoglobulin-secreting ...
Pablo J, van de Berg +3 more
openaire +2 more sources
Idiopathic CD4+ T-cell lymphocytopenia
The Indian Journal of Pediatrics, 2009Idiopathic CD4+ T lymphocytopenia (ICL) is an unusual immune defect in which there is an unexplained deficit of CD4+ T cells, leading to serious opportunistic infections. In view of the rarity of this clinical entity, we report two cases of ICL who presented with low CD4+ count or percentage and various opportunistic infections like candida ...
Aparna, Mukherjee +2 more
openaire +2 more sources
CD4+ T-Cell Differentiation In Vitro
2020CD4+ T helper cells play crucial roles in adaptive immune response against pathogens, as well as in host immune homeostasis. Upon TCR activation, naïve CD4+ T cells differentiate into one of several lineages of Th cells, with hallmark transcription factors, cytokine production, and functions in vivo, according to the particular cytokine milieu.
Wenyong, Yang, Xueying, Chen, Hongbo, Hu
openaire +2 more sources