Body condition, age, and sex as modulators of peripheral blood immune-cell populations and lymphocyte proliferation in cats. [PDF]
Krüger H +3 more
europepmc +1 more source
ABSTRACT Introduction RUNX1 is a commonly mutated transcriptional regulator of hematopoiesis in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Mutated RUNX1 (mRUNX1) may associate with cross‐lineage immunophenotypic aberrancy, presenting potential complications for blast lineage assignment at diagnosis. Methods Clinical and laboratory
Yi Han Xia, Eric McGinnis
wiley +1 more source
Research progress on the role and dysregulation of NK cells in anti-tuberculosis immunity. [PDF]
Zheng Y +10 more
europepmc +1 more source
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver +25 more
wiley +1 more source
Pleural Fluid Cytology Detects Small Cell Carcinoma Transformation in EGFR-Mutant Lung Adenocarcinoma: A Case Report. [PDF]
Zhou H +6 more
europepmc +1 more source
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source
Comprehensive immune profiling of human peripheral blood mononuclear cells using two complementary spectral flow cytometry panels encompassing 60 unique markers. [PDF]
Rietdijk MH +5 more
europepmc +1 more source
Hematopoietic stem and progenitor cell (HSPC) adhesion to the extracellular matrix (ECM) is crucial for their functionality. HSPC adhesion to the ECM component fibronectin is dynamic and goes along with various cell morphologies and podosome‐like structures (PLS).
Miriam Greve +7 more
wiley +1 more source
Immunological profiles of natural killer cells and their subpopulations in overweight and obesity class-I individuals stratified by two-dimensional categories of lipid profiles and body mass index. [PDF]
Surapaitoon A +10 more
europepmc +1 more source
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer +17 more
wiley +1 more source

