Results 181 to 190 of about 68,812 (293)

Efficacy and Safety of Co‐Ablation Combined With Aintilimab for Metastatic Melanoma to the Liver (CryoCheck‐001): A Phase II Trial

MedComm, Volume 7, Issue 10, October 2026.
Liver metastasis is a key driver of immune tolerance in patients with melanoma receiving immune checkpoint inhibitor therapy. This single‐arm phase II trial prospectively investigated the efficacy and safety of co‐ablation combined with sintilimab for liver metastatic melanoma.
Lujun Shen, Letao Lin, Shuanggang Chen, Chen Li, Ruizhi Tang, Lin Xie, Yujia Wang, Yunpeng Li, Hongliang Zou, Dandan Li, Xiaoshi Zhang, Weijun Fan   +11 more
wiley   +1 more source

Adjunctive diagnostic utility of POU2F3 in predominantly pulmonary high-grade neuroendocrine carcinomas with limited or discordant conventional marker expression: a case-control study. [PDF]

Front Med (Lausanne)
Hu X, Wang X, Li C.
europepmc   +1 more source

Associations Between Gut Microbiota and Immune Profiles in Community‐Dwelling Older Adults and the Regulatory Role of Polygonatum odoratum

Aging Cell, Volume 25, Issue 10, October 2026.
Gut Microbiota‐Immune Associations in Community‐Dwelling Older Adults: Role of Polygonatum odoratum. ABSTRACT Aging is often associated with intestinal microbiota imbalance and immune system degeneration. The dysregulation and crosstalk of these two factors markedly elevate the elderly's susceptibility to infections and age‐related diseases ...
Tingting Xia, Hongmei Wu, Tianyi Cui, Wenzhi Yang, Min Zhang, Yuhong Huang, Shengyuan Zhou, Yongsheng Wu, Donglan Yan, Fan Jia, Lin Zhang, Zhi Cui, Jiayao An, Xinqin Zhong, Bin Lv, Xin Zhao, Kaijun Niu, Xiumei Gao   +17 more
wiley   +1 more source

A Distinct Immune Signature Characterizes Cirrhosis in Ethiopian Individuals With Chronic HBV Infection

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 951-964, October 2026.
Cirrhosis patients with untreated HBV in Ethiopia exhibit a distinct immune profile marked by depletion of NK cells, B cells, and T cells, alongside an expanded CD38+HLA‐DR+ CD8 T‐cell population. ABSTRACT Background and Aims The immune cell phenotype of African patients living with chronic hepatitis B virus (HBV) infection is rarely described, despite
Julia MacLeod, Fikadu G. Gudissa, Asiya Jeylan, Nega Berhe, Hailemichael Desalegn, Lasse Rossvoll, Asgeir Johannessen, Niklas K. Björkström, Dag Henrik Reikvam, Annika Niehrs   +9 more
wiley   +1 more source

Long-term depletion of KIR3DL01+ NK cells by adeno-associated viral-vectored antibody delivery alters chronic SIV infection. [PDF]

PLoS Pathog
Sandstrom K, Hagedorn GN, Robinson SC, Katz JE, Prall TM, Wiseman RW, Xie J, Gardner MR, Weiler AM, VanSleet GA, Stroschein SM, Sanchez Hernandez JL, Moy AW, Lifson JD, Capuano Iii SV, Poggi A, Gao G, O'Connor DH, Friedrich TC, Klenchin VA, Evans DT.   +20 more
europepmc   +1 more source

Superficial Ewing Sarcoma of the Rectum: A Case Report and the Utility of Molecular Diagnostics

Journal of Cutaneous Pathology, Volume 53, Issue 10, Page 917-920, October 2026.
ABSTRACT Ewing sarcoma is an undifferentiated small round cell sarcoma that most commonly presents as a malignant bone tumor in pediatric and young adult patients. The diagnosis is typically confirmed by molecular genetic identification of a fusion protein, most commonly involving members of the FET and ETS gene families.
Jessica L. Muldoon, Laura M. Warmke, Ahmed K. Alomari, Rachel P. Kowal   +3 more
wiley   +1 more source

Development of humanized mouse models for the preclinical evaluation of NK cell-based therapies. [PDF]

Front Immunol
Rettman P, Benhamouche-Trouillet S, Azar GA, Bourges D, Fantin V, Sidhu SS, Nicolazzi C.   +6 more
europepmc   +1 more source

Diagnostic utility of inflammatory markers in formalin‐fixed and paraffin‐embedded muscle biopsies for idiopathic inflammatory myopathies

Histopathology, Volume 89, Issue 4, Page 699-709, October 2026.
Formalin‐fixed, paraffin‐embedded (FFPE) muscle tissue supports robust immunohistochemical detection of MHC II, MxA, and p62 with performance comparable to frozen sections. This approach reliably identifies the pathological signatures of inclusion body myositis, dermatomyositis, immune‐mediated necrotizing myopathy, and overlap myositis, enhancing the ...
Chinnawut Suriyonplengsaeng, Jariya Waisayarat   +1 more
wiley   +1 more source

Intestinal resident effector-memory CD4 T cells on the adaptive-innate spectrum comprise IL-18 reactivity and adaptive CMV specificity. [PDF]

Sci Adv
Kammann T, Voigt I, Wild N, Kokkinou E, Cai C, Sekine T, Nilsén V, Weigel W, Tibbitt C, Stamper C, Marchalot A, Bassett J, Kaushal J, Ferreira S, Mouchtaridi E, Raineri EJM, Müller TR, Ballesteros OR, Gao Y, Mily A, Adamo S, Constantz C, Rødahl I, Brownlie D, Michaelsson J, Mjösberg J, Birk M, Buggert M, Marquardt N, Jorns C, Sandberg JK.   +30 more
europepmc   +1 more source

Treatment of Leukemia Cutis Secondary to T‐Cell Prolymphocytic Leukemia With Upadacitinib

eJHaem, Volume 7, Issue 5, October 2026.
Kaela Fraser, Courtney Langille, Luke Y. C. Chen, Kerri Purdy   +3 more
wiley   +1 more source