Results 201 to 210 of about 68,812 (293)

Upper common bile duct neuroendocrine tumor presenting with obstructive jaundice: a case report and literature review. [PDF]

open access: yesFront Oncol
Zhang TG   +9 more
europepmc   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng   +17 more
wiley   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

open access: yesAdvanced Science, Volume 13, Issue 52, 18 September 2026.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun   +6 more
wiley   +1 more source

Bacterial RNA downregulates MHC-I in tumor cell lines, promoting NK response and delaying tumor growth. [PDF]

open access: yesPLoS One
Serafino A   +9 more
europepmc   +1 more source

Expanded Hepatic Progenitor Cells Featured with Aggregation of α‐Synuclein Contribute to Pathologic Bile Duct Regeneration in Biliary Atresia

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
Expanded NCAM1+EpCAM+ hepatic progenitor cells in biliary atresia are characterized by aggregation of α‐synuclein. This pathological protein potentiates cellular susceptibility to GSH‐dependent redox dyshomeostasis, induces unstable biliary cell fate specification, and subsequently drives aberrant biliary regeneration.
Hua Xie   +12 more
wiley   +1 more source

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

open access: yesAnnals of Neurology, Volume 100, Issue 3, Page 547-558, September 2026.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens   +9 more
wiley   +1 more source

Acute Myeloid Leukemia With Florid Plasmacytoid Dendritic Cell Expansion and Aberrant Expression of CD19

open access: yes
International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 919-920, October 2026.
Afshin Shameli, Russell K. Dorer
wiley   +1 more source

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