Results 131 to 140 of about 447,008 (222)

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, Volume 40, Issue 10, Page 5951-5972, October 2026.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

A Distinct Immune Signature Characterizes Cirrhosis in Ethiopian Individuals With Chronic HBV Infection

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 951-964, October 2026.
Cirrhosis patients with untreated HBV in Ethiopia exhibit a distinct immune profile marked by depletion of NK cells, B cells, and T cells, alongside an expanded CD38+HLA‐DR+ CD8 T‐cell population. ABSTRACT Background and Aims The immune cell phenotype of African patients living with chronic hepatitis B virus (HBV) infection is rarely described, despite
Julia MacLeod, Fikadu G. Gudissa, Asiya Jeylan, Nega Berhe, Hailemichael Desalegn, Lasse Rossvoll, Asgeir Johannessen, Niklas K. Björkström, Dag Henrik Reikvam, Annika Niehrs   +9 more
wiley   +1 more source

Diagnostic utility of inflammatory markers in formalin‐fixed and paraffin‐embedded muscle biopsies for idiopathic inflammatory myopathies

Histopathology, Volume 89, Issue 4, Page 699-709, October 2026.
Formalin‐fixed, paraffin‐embedded (FFPE) muscle tissue supports robust immunohistochemical detection of MHC II, MxA, and p62 with performance comparable to frozen sections. This approach reliably identifies the pathological signatures of inclusion body myositis, dermatomyositis, immune‐mediated necrotizing myopathy, and overlap myositis, enhancing the ...
Chinnawut Suriyonplengsaeng, Jariya Waisayarat   +1 more
wiley   +1 more source

Immunophenotypic, Genetic, and Clinical Features Associated With RUNX1 Mutation in Acute Leukemias and Chronic Myeloid Neoplasms

International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1094-1102, October 2026.
ABSTRACT Introduction RUNX1 is a commonly mutated transcriptional regulator of hematopoiesis in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Mutated RUNX1 (mRUNX1) may associate with cross‐lineage immunophenotypic aberrancy, presenting potential complications for blast lineage assignment at diagnosis. Methods Clinical and laboratory
Yi Han Xia, Eric McGinnis
wiley   +1 more source

CD56+, NKp46+ cell line (MZ93) expressing T-cell and myeloid antigens

CD56+, NKp46+ cell line (MZ93) expressing T-cell and myeloid antigens
The MZ93 cell line, established from a patient with CML, expressed CD4, CD7, GD13, CD25, CD33, CD34, CD56 and NKp46. The additional karyotype abnormality of the Ph-positive leukemia cells in vivo, 6p+, was also observed in the MZ93. The early passages of MZ93 expressed CD3 in the cytoplasm, but the late passages did not.
openaire   +1 more source

Diagnostic challenges posed by the wide morphological and immunophenotypic spectrum of plasma cell neoplasms. [PDF]

Blood Res
Chuang SS, Chang CC.
europepmc   +1 more source

CD14+CD56+ Cell Is an Independent Regulatory Monocyte Subpopulation Increased in VKHS Patients Following Glucocorticoids Therapy. [PDF]

Invest Ophthalmol Vis Sci
Wang Z, Jiang H, Deng H, Huang F, Qu S, He S, Yu B, Ye T, Li Z.   +8 more
europepmc   +1 more source

Defective IL-17 production is associated with reduced IL-1β levels in response to <i>Mycobacterium tuberculosis</i> in HIV+ children with latent tuberculosis infection. [PDF]

Front Immunol
Devalraju KP, Mallidi V, Vankayalapati A, Radhakrishnan RK, Bogam AK, Prasad S, Dangatla SV, Joshi S, Nandicoori VK, Valluri VL, Vankayalapati R, Neela VSK.   +11 more
europepmc   +1 more source

Multidisciplinary treatment incorporating autologous DC-CIK cell therapy induces long-term survival in advanced pancreatic cancer: a case report. [PDF]

Front Immunol
Chen S, Xie Y, Xu S, Su L, Xu Y, Liu S, Zheng Q, Liu Q, Sun Y.   +8 more
europepmc   +1 more source

P097 | ROUTINE MULTIPARAMETRIC FLOW CYTOMETRY ANALYSIS QUICKLY RULE OUT HEMATOLOGICAL DISEASES IN CASE OF BONE MARROW NEOPLASTIC INVASION.

Haematologica
Background: Multiparametric flow cytometry (MFC) is a widely employed technique by hematologists for the characterization of cellular populations in peripheral blood, bone marrow (BM) or body cavity fluids samples, particularly in the context of ...
M. Antonacci, M.L. Bisegna, A. Laganà, A. Costa, I. Cordone, M.L. Milani, S. Intoppa, C.A. Germano, M.G. Nardacci, P. De Fabritiis, M. Martelli, M.S. De Propris   +11 more
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