Results 111 to 120 of about 447,008 (222)

Cloning of the Complete Gene for Carcinoembryonic Antigen [PDF]

, 1990
Carcinoembryonic antigen (CEA) is a widely used tumor marker, especially in the surveillance of colonic cancer patients. Although CEA is also present in some normal tissues, it is apparently expressed at higher levels in tumorous tissues than in ...
Schrewe, Heinrich, Bona, Marion, Zimmermann, Wolfgang, Shively, John E., Hassauer, Martin, Hefta, Laura J. F., Maruya, Aiko, Thompson, John A., Kleist, Sabine von   +8 more
core   +1 more source

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

Annals of Neurology, Volume 100, Issue 4, Page 808-823, October 2026.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello, Mario Picozza, Gisella Guerrera, Silvia Corbisiero, Andrea Misiti, Roberta C. Placido, Alice Verdiani, Lorenzo de Marco, Manolo Sambucci, Elena Olivieri, Daniela F. Angelini, Esmeralda Quartuccio, Luca Prosperini, Carla Tortorella, Maria C. Buscarinu, Valeria Zancan, Francesca de Masi, Marco Salvetti, Claudio Gasperini, Giovanna Borsellino, Luca Battistini   +20 more
wiley   +1 more source

Lanreotide, a Somatostatin Analogue, in Advanced Merkel Cell Carcinoma: A Prospective Single‐Arm Phase II Study

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Merkel Cell Carcinoma (MCC) is a rare, aggressive neuroendocrine and epithelial skin cancer. Somatostatin analogues, such as lanreotide, have shown efficacy in managing other neuroendocrine tumors. Retrospective studies suggest that lanreotide may induce partial response or disease stabilization in patients with advanced MCC.
Julie Charles, Aude Belbezier, Stéphane Mouret, Brigitte Dreno, Stéphane Dalle, Céleste Lebbe, Ewa Hainaut‐Wierzbicka, Andreea Stefan, Julie de Quatrebarbes, Olivier Dereure, Ouidad Zehou, Sandrine Mansard, Alain Dupuy, Caroline Dutriaux, Florent Grange, Caroline Gaudy‐Marqueste, Henri Montaudié, Jean‐Philippe Arnault, Yannick Le Corre, Thibault Kervarrec, Jean‐Louis Quesada, Mahtab Samimi, Marie‐Thérèse Leccia, The Group of Cutaneous Oncology of the French Society of Dermatology   +23 more
wiley   +1 more source

The Leucocyte Antigen Factsbook

, 1997
A volume in the popular FactsBook Series, the First Edition of The Leucocyte Antigen FactsBook was hugely successful. The new Second Edition has been completely revised, updated, and expanded by 65% to include new findings and up-to-date key references ...
Barclay, A. Neil, Tomlinson, Michael G., van der Merwe, P. Anton, McKnight, Andrew J., Brown, Marion H., K. Alex Law, S. K. Alex, Van Der Merwe, P Anton   +6 more
core  

Prevalence and clinical impact of CD56 and T‐cell marker expression in acute myeloid leukaemia: A single‐centre retrospective analysis

eJHaem
Flow cytometry‐based immunophenotyping is a mainstay of diagnostics in acute myeloid leukaemia (AML). Aberrant CD56 and T‐cell antigen expression is observed in a fraction subset of AML cases, but the clinical relevance remains incompletely understood ...
Inna Shaforostova, Simon Call, Georg Evers, Christian Reicherts, Linus Angenendt, Matthias Stelljes, Wolfgang E. Berdel, Alexander Pohlmann, Jan‐Henrik Mikesch, Frank Rosenbauer, Georg Lenz, Christoph Schliemann, Klaus Wethmar   +12 more
doaj   +1 more source

SLV‐404, an anti‐RYK antibody–drug conjugate, is effective in Richter transformation patient‐derived xenografts

HemaSphere, Volume 10, Issue 10, October 2026.
Abstract Richter transformation (RT), a highly aggressive lymphoma arising from a preexisting chronic lymphocytic leukemia, represents a major unmet clinical need. Recent data have shown that an antibody–drug conjugate (ADC) targeting the cell‐surface pseudokinase ROR1 is effective in RT patients.
Matilde Micillo, Beatrice Pirajno, Francesco Edoardo Vallone, Victor Navarro‐Tableros, Elisabetta Bolli, Valentina Griggio, Brian J. Lannutti, Katti A. Jessen, Tiziana Vaisitti, Silvia Deaglio   +9 more
wiley   +1 more source

Immunomodulatory properties of extracellular vesicles isolated from bone marrow of patients with neuroblastoma: role of PD-L1 and HLA-G

Frontiers in Immunology
IntroductionExtracellular vesicles (EVs) can be released by any cell and are crucial for cell-to-cell communications. EVs have been characterized in patients with solid and hematological tumors, where they play an important role in tumor progression and ...
Danilo Marimpietri, Maria Valeria Corrias, Gino Tripodi, Roberto Gramignoli, Irma Airoldi, Fabio Morandi   +5 more
doaj   +1 more source

CD56+T Cells Co-Expressing A CD56-Specific Chimeric Antigen Receptor Can Target CD56+ Malignancies Without Autolysis

Biology of Blood and Marrow Transplantation, 2010
Kellar, D., Ang, S., Olivares, S., Dawson, M., Figliola, M., Huls, H., Lee, D., Champlin, R., Cooper, L.   +8 more
openaire   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

EVALUATION OF CD9 & CD56 ANTIGENS EXPRESSION IN ADULT ACUTE MYELOID LEUKAEMIA. [PDF]

International Journal of Advanced Research, 2017
Dr.SubhS.Al. Mudallal., Dr.HindShakerAl. Mamoori., Dr.AlaaShamikh. Hassan.   +2 more
openaire   +1 more source