Results 81 to 90 of about 13,567 (213)

CD59 Protects Primary Human Cerebrovascular Smooth Muscle Cells from Cytolytic Membrane Attack Complex

Brain Sciences
Cerebral amyloid angiopathy is characterized by a weakening of the small- and medium-sized cerebral arteries, as their smooth muscle cells are progressively replaced with acellular amyloid β, increasing vessel fragility and vulnerability to ...
Carson D. Whinnery, Ying Nie, Danilo S. Boskovic, Salvador Soriano, Wolff M. Kirsch   +4 more
doaj   +1 more source

Frequency of paroxysmal nocturnal hemoglobinuria in patients attended in Belém, Pará, Brazil

Revista Brasileira de Hematologia e Hemoterapia, 2011
BACKGROUND: Paroxysmal nocturnal hemoglobinuria is a hematological disease with complex physiopathology. It is genetically characterized by a somatic mutation in the PIG-A gene (phosphatidylinositol glycan anchor biosynthesis, class A), in which the best
Lacy Cardoso de Brito Junior, Maria do Socorro de Oliveira Cardoso, Euzamar Gaby Rocha, Herika Anijar, Mariana Cunha, João Carlos Pina Saraiva   +5 more
doaj   +1 more source

The potential role of cell surface complement regulators and circulating CD4+ CD25+ T-cells in the development of autoimmune myasthenia gravis

Electronic Physician, 2016
Introduction: CD4+CD25+ regulatory T-lymphocytes (T-regs) and regulators of complement activity (RCA) involving CD55 and CD59 play an important role in the prevention of autoimmune diseases.
Mohamed Nasreldin Thabit Hamdoon, Mona Fattouh, Asmaa Nasr El-din, Hassan M. Elnady   +3 more
doaj   +1 more source

Molecular characterization of CD59 and gmfb genes and their differential expression in Piaractus orinoquensis exposed to different conditions of brain injury

Open Veterinary Journal
Background: Neuroinflammation can be triggered by several causes, including traumatic brain injury (TBI) and exposure to toxicants such as chlorpyrifos (CPF), leading to chronic disabilities and substantial healthcare costs.
Rafael Enrique Castro-Vargas, María Paula Herrera-Sanchez, Iang Rondón-Barragan   +2 more
doaj   +1 more source

Antibodies against complement-regulatory proteins on platelets in immune thrombocytopenia

Platelets, 2017
In immune thrombocytopenia (ITP), antibodies reacting with platelet membrane glycoproteins (GP) mediate premature platelet cleavage, resulting in thrombocytopenia and therefore a risk of bleeding.
Ursula Unterberger, Beate Eichelberger, Anja Ulz, Simon Panzer   +3 more
doaj   +1 more source

Early and extensive CD55 loss from red blood cells supports a causal role in malarial anaemia

Malaria Journal, 2011
Background Levels of complement regulatory proteins (CrP) on the surface of red blood cells (RBC) decrease during severe malarial anaemia and as part of cell ageing process.
Gwamaka Moses, Fried Michal, Domingo Gonzalo, Duffy Patrick E   +3 more
doaj   +1 more source

DETECTION AND ISOLATION OF CD59 FROM HUMAN SEMINAL PLASMA

Journal of Research in Medical Sciences, 2002
Introduction. CD59 is one of the complement regulatory proteins (CRPs) which exert inhibitory function by blocking the formation of C5b-9 complex or Membrane Attacks complex (MAC).
A REZAIE, M.H NASR ESFAHANI, MAHMOUD HASHEMI TABAR, H BAHRAMIAN, F ORAIZI   +4 more
doaj  

Expression of the membrane complement regulatory proteins (CD55 and CD59) in human thymus.

Folia Histochemica et Cytobiologica, 2007
CD59 is one of the key molecules involved in cell protection against autologus complement. The fact that complement regulatory proteins are able to prevent hyperacute rejection of organs in pig to primate model, raises the question of possible complement
Agnieszka Kinsner, Sandra Coecke, Iwona Grabska-Liberek, Grzegorz Wilczyński, Aleksander Wasiutyński, Dariusz Sladowski, Iwona Kochanowska   +6 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source