Identification of CD320, SLC44A1 and TNFRSF13B as potential novel therapeutic targets for CAR T-cell therapy in multiple myeloma [PDF]
Frontiers in MedicineIntroductionMultiple myeloma (MM) remains incurable despite effective therapies, with most patients eventually relapsing. Chimeric antigen receptor (CAR) T-cell therapy has improved treatment options but is limited by antigen escape and lack of durable ...
Francesca Garofano +7 more
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Proteomic Analysis of Endothelial Activation Induced by Adult Angiostrongylus vasorum Homogenate: Insights into Vascular Remodeling and Hemostatic Imbalance [PDF]
AnimalsThe interaction between Angiostrongylus vasorum and the vascular endothelium of the host plays a key role in the pathogenesis of canine angiostrongylosis. The adult stage of A.
Manuel Collado-Cuadrado +9 more
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Immune response and histology of humoral rejection in kidney transplantation
Nefrología (English Edition), 2016 The adaptive immune response forms the basis of allograft rejection. Its weapons are direct cellular cytotoxicity, identified from the beginning of organ transplantation, and/or antibodies, limited to hyperacute rejection by preformed antibodies and not ...
Miguel González-Molina +7 more
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Frequency of paroxysmal nocturnal hemoglobinuria in patients attended in Belém, Pará, Brazil
Revista Brasileira de Hematologia e Hemoterapia, 2011 BACKGROUND: Paroxysmal nocturnal hemoglobinuria is a hematological disease with complex physiopathology. It is genetically characterized by a somatic mutation in the PIG-A gene (phosphatidylinositol glycan anchor biosynthesis, class A), in which the best
Lacy Cardoso de Brito Junior +5 more
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Function of complement regulatory proteins in immunity of reproduction: a review
Czech Journal of Animal Science, 2005 Humoral immunity has an important role during the maturation and development of the functional properties of spermatozoa. Spermatozoa may be exposed to antisperm antibodies in semen and in cervical, ovarian follicular and fallopian fluid.
J. Valentovičová +2 more
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Potential benefits and risks of clinical xenotransplantation [PDF]
, 2012 The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
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Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]
, 2016 Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J. +7 more
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Optimizing complement-activating antibody-based cancer immunotherapy: a feasible strategy?
Journal of Translational Medicine, 2004 Passive immunotherapy with monoclonal antibodies (mAb) targeted to specific tumor-associated antigens is amongst the most rapidly expanding approaches to biological therapy of cancer.
Maio Michele +2 more
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Wavelet feature extraction and genetic algorithm for biomarker detection in colorectal cancer data [PDF]
, 2012 Biomarkers which predict patient’s survival can play an important role in medical diagnosis and treatment. How to select the significant biomarkers from hundreds of protein markers is a key step in survival analysis.
Aickelin, Uwe +3 more
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Exosomes: Versatile Nano Mediators of Immune Regulation. [PDF]
, 2019 One of many types of extracellular vesicles (EVs), exosomes are nanovesicle structures that are released by almost all living cells that can perform a wide range of critical biological functions.
Cacalano, Nicholas A +4 more
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