Results 11 to 20 of about 170,506 (176)

Association of Blood Group Antigen CD59 with Disease [PDF]

Transfusion Medicine and Hemotherapy, 2022
In 2014, the membrane-bound protein CD59 became a blood group antigen. CD59 has been known for decades as an inhibitor of the complement system, located on erythrocytes and on many other cell types. In paroxysmal nocturnal haemoglobinuria (PNH), a stem cell clone with acquired deficiency to express GPI-anchored molecules, including the complement ...
Weinstock, Christof
core   +5 more sources

Expression of the DAF (CD55) and CD59 antigens during normal hematopoietic cell differentiation

Journal of Leukocyte Biology, 1992
Abstract Expression of decay-accelerating factor (DAF or CD55) and of CD59 during hematopoietic cell development in normal bone marrow and on peripheral blood leukocytes were characterized by three-color immunofluorescence experiments.
L W, Terstappen, M, Nguyen, H M, Lazarus, M E, Medof   +3 more
openaire   +3 more sources

Six monoclonal antibodies to the CD59 antigen [PDF]

Immunohematology, 1993
Abstract CD59 defines an N -glycosylated glycoprotein expressed on various hemopoietic cells. It is anchored to the cell membrane by a glycosylphosphatidylinositol linkage and restricts the action of homologous complement.
J A, Bryant, A, Fletcher, F F, Yuan
openaire   +2 more sources

A new blood group antigen is defined by anti‐CD59, detected in a CD59‐deficient patient [PDF]

Transfusion, 2014
BackgroundCD59 is a cell surface glycoprotein of approximately 20 kDa limiting the lytic activity of the terminal complement complex C5b‐9. Although CD59 is known as a red blood cell (RBC) antigen defined by monoclonal antibodies, it so far has not been identified as a blood group antigen, since the description of a human alloantibody was missing.
Anliker, Markus, von Zabern, Inge, Höchsmann, Britta, Kyrieleis, Henriette, Dohna-Schwake, Christian, Flegel, Willy A, Schrezenmeier, Hubert, Weinstock, Christof   +7 more
openaire   +2 more sources

Early and extensive CD55 loss from red blood cells supports a causal role in malarial anaemia. [PDF]

, 2011
BACKGROUND\ud \ud Levels of complement regulatory proteins (CrP) on the surface of red blood cells (RBC) decrease during severe malarial anaemia and as part of cell ageing process.
Fried, Michal, Moses Gwamaka, Michal Fried, Duffy, Patrick E, Patrick E Duffy, Gwamaka, Moses, Gonzalo Domingo, Domingo, Gonzalo   +7 more
core   +1 more source

Endothelial cells as targets for antigen-specific cytotoxic T lymphocytes [PDF]

, 2010
BACKGROUND: In this study we have examined human vascular endothelial cells as targets for antigen-specific cytotoxic T lymphocytes (CTL). Vascular endothelial cells (EC) act as the major interface between blood and tissues and are crucial for the ...
Thommen, Daniela Stefanie
core   +1 more source

Antigen‐presenting cell exosomes are protected from complement‐mediated lysis by expression of CD55 and CD59 [PDF]

European Journal of Immunology, 2003
AbstractExosomes are secreted nanometer‐sized vesicles derived from antigen‐presenting cells, which have attracted recent interest as they likely play important roles in immune regulation, and their use as cell‐free tools for immunotherapy has been proposed.
Aled, Clayton, Claire L, Harris, Jacquelyn, Court, Malcolm D, Mason, B Paul, Morgan   +4 more
openaire   +2 more sources

Comparison of schistosoma mansoni soluble cercarial antigens and soluble egg antigens for serodiagnosing schistosome infections [PDF]

, 2011
A Schistosoma mansoni cercarial antigen preparation (cercarial transformation fluid – SmCTF) was evaluated for detection of anti-schistosome antibodies in human sera in 4 collaborating laboratories.
Dawson, E., Smith, H., Ji, Minjun, Mike Doenhoff, Emily Dawson, Claire Alexander, Gilis, Henk, van Gool, T., Cara Aitken (135264), Grant Spence, Aitken, Cara, Aitken, C., Bailey, W., Cara Aitken, Minjun Ji (135275), Spence, G., Spence, Grant, Henk Gilis, Tom van Gool, Doenhoff, M., Claire Alex, Wendi Bailey, Mike Doenhoff (135259), Gilis, H., Huw Smith, Doenhoff, Mike, van Gool, Tom, Dawson, Emily, Smith, Huw, Tom van Gool (135295), Henk Gilis (135283), Claire Alexander (20985), Minjun Ji, Bailey, Wendi, Grant Spence (135288), Alexander, C., Ji, M., Huw Smith (135256), Wendi Bailey (135270), Emily Dawson (135279), Alexander, Claire   +40 more
core   +2 more sources

CD59 (CD59 molecule, complement regulatory protein) [PDF]

, 2013
Review on CD59 (CD59 molecule, complement regulatory protein), with data on DNA, on the protein encoded, and where the gene is ...
Donev, RM, Kolev, MV
core   +1 more source

Immunity to Intracellular Salmonella Depends on Surface-associated Antigens [PDF]

, 2012
Invasive Salmonella infection is an important health problem that is worsening because of rising antimicrobial resistance and changing Salmonella serovar spectrum.
Rizos Konstantin, Beatrice Claudi (126116), Dirk Bumann (126124), Dirk Bumann, Somedutta Barat (126107), Barat, Somedutta, Rizos, K., Bumann, D., Schemmer, Anne K, Claudi Beatrice, Neil Burton (126123), Anne K Schemmer, Barat Somedutta, Dennis Kirchhoff (126121), Somedutta Barat, Alexander Schmidt (68515), Kirchhoff, D., Alain Mazé, Willer, Yvonne, Anne K. Schemmer (126119), Kirchhoff Dennis, Rizos, Konstantin, Dennis Kirchhoff, Bumann, Dirk, Burton Neil, Schemmer, A., Claudi, B., Mazé, Alain, Schmidt Alexander, Schemmer Anne K., Yvonne Willer (126110), Konstantin Rizos (126113), Willer Yvonne, Yvonne Willer, Willer, Y., Burton, Neil, Bumann Dirk, Alexander Schmidt, Mazé Alain, Beatrice Claudi, Schmidt, A., Alain Mazé (126117), Mazé, A., Claudi, Beatrice, Kirchhoff, Dennis, Barat, S., Konstantin Rizos, Burton, N., Schemmer, Anne K., Schmidt, Alexander, Neil Burton   +50 more
core   +2 more sources