Results 161 to 170 of about 36,435 (217)

Youth-associated protein TIMP2 regulates microglial state and function in healthy and aged mice. [PDF]

Nat Commun
Hemmer BM, Philippi SM, Ferreira AC, Petridis SF, Phan A, Castellano JM.   +5 more
europepmc   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Environmental enrichment modulates chronic poststroke inflammation and links white matter TREM2-positive microglia in recovery in mice. [PDF]

Neuroprotection
Camprubí-Ferrer L, Kolbay ÖK, Quattromani MJ, Wieloch T, Ruscher K, Deierborg T.   +5 more
europepmc   +1 more source

A novel <i>Bacillus megaterium</i>/ω-3 PUFA synbiotic attenuates colon inflammation and promotes a pro-resolving macrophage profile ex-vivo. [PDF]

Front Immunol
Prete V, Picone F, Abate AC, Speckmann B, Berngruber T, Iside C, Venturini E, Vecchione C, Ciacci C, Carrizzo A.   +9 more
europepmc   +1 more source

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak, Reinhard Dummer, Egle Ramelyte   +2 more
wiley   +1 more source

Lysophosphatidic acid drives to mirror-image pain via corpus callosum-mediated propagation of inflammatory responses. [PDF]

Commun Biol
Neyama H, Kizu R, Maeda R, Ueda H, Sugiura Y.   +4 more
europepmc   +1 more source

FOXC1: A Key Transcription Factor of VSMC‐Derived Foam Cell Formation in Atherosclerotic Plaque Instability

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The instability of atherosclerotic plaques, particularly intraplaque hemorrhage (IPH), drives life‐threatening cardiovascular events, a process in which vascular smooth muscle cell (VSMC)‐derived foam cells play a significant role. We aim to identify key biomarkers associated with VSMC‐derived foam cells and IPH by analyzing data from human ...
Ling‐Lin Qian, Xue‐Ling Li, Li‐Hong Wang, Wei Yang, Yu Jiang   +4 more
wiley   +1 more source

Inflammatory Memory of Adipose Tissue Macrophages: From CD68 Footprint to Cardiometabolic and Cancer Risk During Weight Cycling. [PDF]

Int J Mol Sci
Tomić Naglić D, Manojlović M, Pejaković S, Vuković N, Grbić T, Milanović O, Mirković M, Maričić S, Maksimović T, Milankov A.   +9 more
europepmc   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Atherogenic-like lesions associated with a progressive chronic vascular degeneration in a rat model of repetitive low-level blast brain injury. [PDF]

J Neuropathol Exp Neurol
Gama Sosa MA, De Gasperi R, Lind RH, Pryor D, Perez GM, Perez Garcia GS, Abutarboush R, Kawoos U, Zhu CW, Janssen WGM, Hof PR, Ahlers ST, Elder GA.   +12 more
europepmc   +1 more source