Results 241 to 250 of about 36,481 (278)

Targeting CD73 and correcting adenosinergic signaling in critically ill patients. [PDF]

open access: yesFront Pharmacol
Lunderberg JM   +5 more
europepmc   +1 more source

CD73 blockade enhances antitumor efficacy of oHSV in solid tumors by increasing macrophage-mediated antigen presentation. [PDF]

open access: yesJ Immunother Cancer
Murphy SA   +8 more
europepmc   +1 more source

Spatiotemporal dynamics of ecto-5'-nucleotidase (CD73) in mouse retina under physiological conditions. [PDF]

open access: yesDevelopment
Ishii R   +6 more
europepmc   +1 more source

Ecto-5'-nucleotidase/CD73 reduces COX-2 expression in activated macrophages. [PDF]

open access: yesSci Rep
Rahman MM   +5 more
europepmc   +1 more source

CD8 T Cell Sensing of Type I Interferon Impacts Anergy. [PDF]

open access: yesEur J Immunol
Haefke AS   +14 more
europepmc   +1 more source
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CD73: a potent suppressor of antitumor immune responses

Trends in Immunology, 2012
Tumors use several strategies to evade immunosurveillance. One such mechanism is the generation of adenosine within the tumor microenvironment, which potently suppresses antitumor T cell responses. Adenosine within the tumor is generated by CD73, a membrane-bound nucleotidase that is expressed by tumor cells, suppressive immune subsets such as T ...
Paul A Beavis   +2 more
exaly   +6 more sources

Functional expression of CD73 on human natural killer cells

open access: yesCancer Immunology, Immunotherapy, 2022
The production of adenosine by CD73 on cancer cells in the tumor microenvironment is a recognized immunosuppressive mechanism contributing to immune evasion in many solid tumors.
Jiao Wang   +2 more
exaly   +2 more sources

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