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Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1
The Lancet, 1996Summary Background Although lymphocytes expressing the CD4 surface receptor for HIV-1 have been identified as the principal target of the virus, the extent to which infection of other cell types of the immune system contributes to immunodeficiency is unknown.
WJ Livingstone +4 more
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Decreases of CD4‐ and CD8‐positive T lymphocytes in retired chromate workers
American Journal of Industrial Medicine, 1995AbstractTo investigate the effects of chromates on the human immune system, we measured total T lymphocytes and their two major subpopulations (CD4 + and CD8 + T lymphocytes) in the peripheral blood of 19 retired male workers who had been exposed to chromate at a chemical plant.
T, Tanigawa +4 more
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Autoantibodies against CD4- and CD8-Positive T Lymphocytes in HIV-Infected Hemophilia Patients
Vox Sanguinis, 1989The presence of IgG, IgM, C3d, or gp120 on the surface of T lymphocytes was analyzed by flow cytometry in blood samples from 73 hemophilia patients and 56 healthy controls. IgG and IgM autoantibodies against CD4+ lymphocytes were found in HIV + patients but not in HIV-patients or healthy controls (p less than 0.001).
V, Daniel +3 more
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Journal of Clinical Immunology, 2003
The pathogenic mechanism for hepatocellular damage in hepatitis C virus (HCV) infection has not been clearly understood. Analysis of costimulatory molecules on lymphocytes may give us insight into the pathogenic mechanism of hepatocellular damage in HCV infection.
Kazutaka, Kurokohchi +10 more
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The pathogenic mechanism for hepatocellular damage in hepatitis C virus (HCV) infection has not been clearly understood. Analysis of costimulatory molecules on lymphocytes may give us insight into the pathogenic mechanism of hepatocellular damage in HCV infection.
Kazutaka, Kurokohchi +10 more
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Radiosensitivity of CD4 or CD8 Positive Human T-Lymphocytes by an in Vitro Colony Formation Assay
Radiation Research, 1990The recent development of an in vitro lymphocyte colony assay makes it possible to examine variations in the radiosensitivity of humans using peripheral blood lymphocytes (PBL) instead of the skin fibroblast assay. Our recent study (M. Hakoda et al., Mutat. Res.
N, Nakamura, Y, Kusunoki, M, Akiyama
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Mink infected with aleutian disease virus have an elevated level of CD8-positive T-lymphocytes
Veterinary Immunology and Immunopathology, 1989Lymphocytes, monocytes, granulocytes, B-lymphocytes and CD8-positive T-lymphocytes of non-infected mink and mink infected with Aleutian disease virus (ADV) were measured by flow cytometry. The gammaglobulin levels of the sera were also measured. Besides development of hypergammaglobulinaemia in the infected mink, the most pronounced finding was that ...
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Egyptian Journal of Hospital Medicine
Background: Bladder cancer (BC) is one of the most prevalent malignant tumours in Egypt. Several studies reported talented results using combined tri-modality therapy in muscle invasive bladder cancer (MIBC) with transurethral resection, radiation therapy and platinum-based systemic chemotherapy.
Hamza, Mona Atta +4 more
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Background: Bladder cancer (BC) is one of the most prevalent malignant tumours in Egypt. Several studies reported talented results using combined tri-modality therapy in muscle invasive bladder cancer (MIBC) with transurethral resection, radiation therapy and platinum-based systemic chemotherapy.
Hamza, Mona Atta +4 more
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Transplantation, 1989
We have demonstrated by two-color flow cytometry that allosensitized human suppressor T cells thwart progression of alloactivated T cells into the G1B stage of the cell cycle, and consequently prevent the expression of transferrin receptors on the majority of alloreactive MLR responder cells (P less than 0.005).
R, Loertscher, T B, Strom
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We have demonstrated by two-color flow cytometry that allosensitized human suppressor T cells thwart progression of alloactivated T cells into the G1B stage of the cell cycle, and consequently prevent the expression of transferrin receptors on the majority of alloreactive MLR responder cells (P less than 0.005).
R, Loertscher, T B, Strom
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Preferential clonogenic deficit of CD8-positive T-lymphocytes infiltrating human solid tumors.
Cancer research, 1989The vast majority of tumor infiltrating lymphocytes (TIL) are either CD4+ or CD8+ T-lymphocytes. In order to examine directly the functional capabilities of the individual CD4+ and CD8+ TIL subsets we performed cell sorting of double immunofluorescence-labeled TIL recovered from 15 biopsies by enzyme digestion.
S, Miescher +5 more
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