Results 241 to 250 of about 14,873,839 (295)

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

Advanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun, Ruiqi Wu, Qingshuang Tang, Yunli Xu, Wanrui Shi, Mengxin Wang, Haonan Wang, Yan Luo, Cheng Ma, Xiaolong Liang   +9 more
wiley   +1 more source

Association Between Different Antiretroviral Therapy Regimens and Adipokine Secretion Profile in HIV-Infected Individuals. [PDF]

Int J Mol Sci
Szymańska B, Knysz B, Piwowar A.
europepmc   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Interferon regulatory factors orchestrate CD8⁺ T cell function (Review). [PDF]

Int J Mol Med
Wang FX, Yang CL, Rong SJ, Chen QJ, Yue XT, Sun F.   +5 more
europepmc   +1 more source

Morphologic mimicry of cutaneous T-cell lymphoma as classic Hodgkin lymphoma-a case report. [PDF]

J Hematop
Lunt J, Burns R, Schammel CM, Knight J.
europepmc   +1 more source

Advancements in understanding and treating CXCL16/CXCR6 in tumors and in inflammatory diseases: a narrative review. [PDF]

Front Immunol
Li X, Liu S, Qian D, Huang M, Na M, Mo Q, Ju M, Ge J, Gao J, Zhang X, Wan C.   +10 more
europepmc   +1 more source

Impact of sialyltransferase deletion in mature T cells on control of subcutaneous and metastatic cancers. [PDF]

Glycobiology
Wang X, Paulson JC.
europepmc   +1 more source

Effect of antiretroviral therapy on gut microbiota, immune activation, and inflammatory markers in newly diagnosed HIV patients. [PDF]

Front Cell Infect Microbiol
Márquez-Ruiz D, Illanes-Álvarez F, Martín-Aspas A, Tinoco Racero I, Campaña-Gómez I, Guerra-González R, Romero-Palacios A, Márquez-Coello M, Cuesta-Sancho S, Girón-González JA.   +9 more
europepmc   +1 more source

PD-1 and TIGIT coexpression enables selective enrichment of clonally expanded tumor-reactive CD8 T cells for melanoma TIL therapy. [PDF]

J Transl Med
Ducoin K, Beauvais T, Goward J, Ahondo M, Lambot S, Mordelet A, Daminette A, Thabot M, Deng J, Tian S, Rulli S, Quereux G, Khammari A, Labarrière N.   +13 more
europepmc   +1 more source