Results 21 to 30 of about 291,218 (316)

Erythrodermic CD4/CD8 Double-Negative Mycosis Fungoides: A Case Report

Case Reports in Oncology, 2021
Cutaneous T-cell lymphoma (CTCL) describes a group of lymphoproliferative disorders characterized by localization of neoplastic T lymphocytes to the skin. Mycosis fungoides (MF) represents the most common type of CTCL and accounts for ∼60% of all primary
Monira Abdullah Alnasser, Nour Marwan AlKhawajah, Nada Ghazi AlQadri, Asem Mustafa Shadid, Fahad M. Alsaif   +4 more
doaj   +1 more source

USE OF TCR Vβ2 REPERTOIRES TO DIFFERENTIATE CD8 T-CELL LYMPHOMAS FROM INFECTIOUS DISEASE REACTIVE LYMPHOCYTOSIS

Hematology, Transfusion and Cell Therapy, 2021
Introduction: Reactive lymphocytosis can be difficult to differentiate from clonal lymphocytosis, especially when it involves CD8 positive T-lymphocytes. Leukemias and lymphomas cause an increase in this population at the expense of replication of clonal
DC Oliveira, YC Schluga, JLP Justus, MP Beltrame, AP Azambuja   +4 more
doaj   +1 more source

T lymphocytes infiltrating advanced grades of cervical neoplasia. CD8-positive cells are recruited to invasion [PDF]

Cancer, 1995
Impaired cellular immunity appears to be a risk factor for progression of cervical neoplasia, but the immunobiology of neoplastic progression is poorly understood. The objective of this study was to characterize the subpopulations of T lymphocytes that infiltrate various grades of cervical neoplasia including metaplasia to invasive cancer in ...
R P, Edwards, K, Kuykendall, P, Crowley-Nowick, E E, Partridge, H M, Shingleton, J, Mestecky   +5 more
openaire   +2 more sources

Inflammatory and immune checkpoint markers are associated with the severity of aortic stenosisCentral MessagePerspective

JTCVS Open, 2021
Objective: Aortic stenosis (AS) is a disease characterized by narrowing of the aortic valve (AV) orifice. In relation to this disease, the purpose of this study was to elucidate the relationships among factors such as expression of programmed cell death ...
Bilguun Erkhem-Ochir, MD, Wataru Tatsuishi, MD, PhD, Takehiko Yokobori, MD, PhD, Tsukasa Ohno, MD, PhD, Kyohei Hatori, MD, PhD, Tadashi Handa, PhD, Tetsunari Oyama, MD, PhD, Ken Shirabe, MD, PhD, Hiroshi Saeki, MD, PhD, Tomonobu Abe, MD, PhD   +9 more
doaj   +1 more source

Causes of T lymphocyte activation in HIV-infected patients coinfected with hepatitis C virus [PDF]

Терапевтический архив, 2016
Aim. To establish the causes of T lymphocyte activation in human immunodeficiency virus (HIV)-infected patients coinfected with hepatitis C (HCV) who are adherent to their antiretroviral therapy regimen and interferon untreated.
K V Shmagel, N G Shmagel, L B Korolevskaya, E V Saydakova, V A Chereshnev   +4 more
doaj   +1 more source

Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the α3 domain of MHC I molecules [PDF]

, 1991
THE α1 and α2 domains of major histocompatibility complex (MHC) class I molecules function in the binding and presentation of foreign peptides to the T-cell antigen receptor and control both negative and positive selection of the T-cell repertoire ...
AM Norment, Carla J. Aldrich, CJ Aldrich, CJ Aldrich, HR MacDonald, HS Teh, HS Teh, HS Teh, IA Stroynowski, IS Trowbridge, Iwona Stroynowski, J Sprent, James Forman, JC Zuniga-Pflucker, JM Connolly, Lee Hood, M Reddehase, MA Alexander, PJ Bjorkman, R Salter, RC Budd, Robert E. Hammer, RR Zamoyska, S Marusic-Galesic, S Qin, Sharon Jones-Youngblood, UH Koszinowski, Ulrich Koszinowski, W-P Fung-Leung, WR Lie, WR Lie   +30 more
core   +1 more source

Spinal Cord T-Cell Infiltration in the Rat Spared Nerve Injury Model: A Time Course Study. [PDF]

, 2016
The immune system is involved in the development of neuropathic pain. In particular, the infiltration of T-lymphocytes into the spinal cord following peripheral nerve injury has been described as a contributor to sensory hypersensitivity.
Clarke, C.B., Decosterd, I., Gattlen, C., Gosselin, R.D., Kirschmann, G., Pertin, M., Piller, N., Suter, M.R.   +7 more
core   +2 more sources

A Study on Tumor-Infiltrating Lymphocytes in Different Subtypes of Breast Cancer [PDF]

Journal of Biomedical & Clinical Research, 2021
The study aimed to investigate immune cell infiltration in different subtypes of breast cancer (BC). Retrospectively were selected 100 patients with primary BC, grouped into four molecular surrogate subtypes (Luminal A and Luminal B-like, HER2-positive ...
Polina Dimitrova, Savelina Popovska, Ivan Ivanov   +2 more
doaj   +3 more sources

A murine intestinal intraepithelial NKp46-negative innate lymphoid cell population characterized by group 1 properties [PDF]

, 2017
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal V gamma 3 T cells, intestinal intraepithelial CD8 alpha alpha(+) T lymphocytes, and CD49a(+) liver natural killer (NK) cells.
Biswas, Aindrila, Diefenbach, Andreas, Dunay, Ildiko Rita, Filtjens, Jessica, Gronke, Konrad, Kerre, Tessa, Leclercq, Georges, Martens, Liesbet, Matthys, Patrick, Plum, Jean, Saeys, Yvan, Taghon, Tom, Taveirne, Sylvie, Van Acker, Aline, Van Ammel, Els, Vandekerckhove, Bart   +15 more
core   +2 more sources

Tailoring CD19xCD3-DART exposure enhances T-cells to eradication of B-cell neoplasms. [PDF]

, 2018
Many patients with B-cell malignancies can be successfully treated, although tumor eradication is rarely achieved. T-cell-directed killing of tumor cells using engineered T-cells or bispecific antibodies is a promising approach for the treatment of ...
Aliberti S, Bareja R, Bonvini E, Bruna R, Brusa D, Chiaretti S, Chichili GR, Cignetti A, Circosta P, Deaglio S, Elemento O, Elia AR, Foà R, Giacomo FD, Gottardi D, Guarini AR, Inghirami G., Johnson S, Kyriakides PW, Landra I, Machiorlatti R, Massaia M, Monteleone E, Moore PA, Todaro M   +24 more
core   +1 more source