Results 41 to 50 of about 291,218 (316)

Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma. [PDF]

open access: yesPLoS ONE, 2014
The ability of neural stem/progenitor cells (NSCs) to self-renew, migrate to damaged sites, and differentiate into neurons has renewed interest in using them in therapies for neurodegenerative disorders.
Shuxian Hu   +3 more
doaj   +1 more source

Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection. [PDF]

open access: yes, 2007
BackgroundWe reported previously on the emergence and clinical implications of simian immunodeficiency virus (SIVmac251) mutants with a K65R mutation in reverse transcriptase (RT), and the role of CD8+ cell-mediated immune responses in suppressing ...
Bischofberger, Norbert   +10 more
core   +3 more sources

Effects of dietary conjugated linoleic acids on cellular immune response of piglets after cyclosporin A injection

open access: yesAnimal, 2016
The present study investigated the effects of dietary conjugated linoleic acid (CLA) on the cellular immune response of piglets after cyclosporin A (CsA) treatment.
Y.X. Liu, K.Y. Zhu, Y.L. Liu, D.F. Jiang
doaj   +1 more source

CD4-Positive and CD8-Positive Cytotoxic T Lymphocytes Contribute to Human Papillomavirus Type 16 E6 and E7 Responses [PDF]

open access: yesClinical Diagnostic Laboratory Immunology, 1999
ABSTRACTCytotoxic T-lymphocyte (CTL) responses to E6 and E7 were previously shown to be more commonly detectable in human papillomavirus type 16 (HPV-16)-positive women without squamous intraepithelial neoplasia (SIL) than in HPV-16-positive women with SIL (M. Nakagawa, D. P. Stites, S. Farhat, J. R. Sisler, B. Moss, F. Kong, A. B. Moscicki, and J.
M, Nakagawa   +4 more
openaire   +2 more sources

Primary cutaneous aggressive epidermotropic cytotoxic T-cell lymphomas: reappraisal of a provisional entity in the 2016 WHO classification of cutaneous lymphomas. [PDF]

open access: yes, 2017
Primary cutaneous CD8-positive aggressive epidermotropic T-cell lymphoma is a rare and poorly characterized variant of cutaneous lymphoma still considered a provisional entity in the latest 2016 World Health Organization Classification of Cutaneous ...
Duvic, Madeleine   +19 more
core   +1 more source

Clinical Significance of Programmed Death Ligand‑1 and Intra-Tumoral CD8+ T Lymphocytes in Ovarian Carcinosarcoma.

open access: yesPLoS ONE, 2017
Ovarian carcinosarcoma (OCS) accounts for high mortality and lacks effective therapeutic methods. So far, we lack reliable biomarkers capable of predicting the risk of aggressive course of the disease.
Jun Zhu   +5 more
doaj   +1 more source

Simultaneous expression of CD4 and CD8 antigens by a substantial proportion of resting porcine T lymphocytes [PDF]

open access: yes, 1987
The existence of four subpopulations in resting porcine T lymphocytes is documented. In addition to the two known subpopulations which are typified by a mutually exclusive expression of either the CD8 or the CD4 differentiation antigen, CD4-CD8+ and CD4 ...
Bevan   +19 more
core   +3 more sources

Phenotyping renal leukocyte subsets by four-color flow cytometry: Characterization of chemokine receptor expression [PDF]

open access: yes, 2003
To investigate mechanisms of cell-mediated injury in renal inflammatory disease it is critical to determine the surface phenotype of infiltrating renal leukocyte subsets.
Anders, Hans-Joachim   +5 more
core   +1 more source

Siah2 control of T-regulatory cells limits anti-tumor immunity. [PDF]

open access: yes, 2020
Understanding the mechanisms underlying anti-tumor immunity is pivotal for improving immune-based cancer therapies. Here, we report that growth of BRAF-mutant melanoma cells is inhibited, up to complete rejection, in Siah2-/- mice.
Aifantis, Ioannis   +15 more
core   +2 more sources

Analysis of CD57+ natural killer cells and CD8+ T lymphocytes in periapical granulomas and radicular cysts

open access: yesBrazilian Oral Research, 2017
: The aim of this study was to compare the number of CD57+ natural killer (NK) cells and CD8+ T lymphocytes between periapical granulomas (PGs) and radicular cysts (RCs). Twenty-fives cases of PGs and 25 of RCs were submitted to histological analysis and
Luiz Arthur Barbosa da Silva   +5 more
doaj   +1 more source

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