Results 61 to 70 of about 267,552 (285)

Effector cell mediated cytotoxicity measured by intracellular Granzyme B release in HIV infected subjects

Biological Procedures Online, 2003
CD8+ cytotoxic T lymphocyte (CTL) activity is currently believed to be one of the key immunologic mechanisms responsible for the prevention or attenuation of HIV-1 infection.
Mahajan Supriya D., Aalinkeel Ravikumar, Schwartz Stanley A., Chawda Ram P., Nair Madhavan P.N.   +4 more
doaj   +1 more source

The relationship between absolute counts of lymphocyte subsets and clinical features in patients with pulmonary tuberculosis

The Clinical Respiratory Journal, 2022
Background The aim of the present study is to investigate the clinical value and characteristics of peripheral blood lymphocyte subsets in patients with pulmonary tuberculosis (PTB) using flow cytometry.
Hui‐Ru An, Xue‐Juan Bai, Jian‐Qin Liang, Tao Wang, Zhong‐Yuan Wang, Yong Xue, Yin‐Ping Liu, Lan Wang, Xue‐Qiong Wu   +8 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Inflammatory and immune checkpoint markers are associated with the severity of aortic stenosisCentral MessagePerspective

JTCVS Open, 2021
Objective: Aortic stenosis (AS) is a disease characterized by narrowing of the aortic valve (AV) orifice. In relation to this disease, the purpose of this study was to elucidate the relationships among factors such as expression of programmed cell death ...
Bilguun Erkhem-Ochir, MD, Wataru Tatsuishi, MD, PhD, Takehiko Yokobori, MD, PhD, Tsukasa Ohno, MD, PhD, Kyohei Hatori, MD, PhD, Tadashi Handa, PhD, Tetsunari Oyama, MD, PhD, Ken Shirabe, MD, PhD, Hiroshi Saeki, MD, PhD, Tomonobu Abe, MD, PhD   +9 more
doaj  

Immunohistochemical Analysis of Natural Killer Cells and CD8+ T Lymphocytes in Lower Lip Squamous Cell Carcinoma [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Inflammatory cells may influence the growth of malignant neoplasms through pro and anti-tumour effects. Natural Killer (NK) cells and cytotoxic T lymphocytes (CD8+) are the main effector cells against cancer.
Thais Aline Oliveira Maciel, Marianna Sampaio Serpa, Rodrigo Porpino Mafra, Amanda Katarinny Goes Gonzaga, Lélia Batista de Souza, Leão Pereira Pinto   +5 more
doaj   +1 more source

Effect Of Mangosteen (Garcinia Mangostana) Peel Extract Towards CD8 + T Lymphocytes And CD8 + CD38 Expression In HIV Patients With Antiretroviral Therapy [PDF]

, 2015
Background : HIV/AIDS still being an emerging disease and the AIDS epidemic in Indonesia is one of the fastest growing in Asia. Humans infected with HIV have been shown to be under chronic oxidative stress.
Komala, Ika
core  

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Identification of CD8+ T cell subsets that normalize in early-treated people living with HIV receiving antiretroviral therapy

AIDS Research and Therapy, 2022
Background Although combined antiretroviral therapy (cART) has decreased the mortality associated with HIV infection, complete immune reconstitution is not achieved despite viral suppression.
Federico Perdomo-Celis, David Arcia-Anaya, Juan Carlos Alzate, Paula A. Velilla, Francisco J. Díaz, Maria Paulina Posada, María T. Rugeles, Natalia A. Taborda   +7 more
doaj   +1 more source

Analysis of Cellular Component Indicators of Immune Status of Rhesus Macaques

Проблемы особо опасных инфекций, 2021
Objective. Selection of indicators of lymphocyte populations in rhesus macaques determined by flow cytometry to evaluate variations of cellular constituent of their immune status.Materials and methods.
G. V. Borisevich, S. L. Kirillova, O. N. Sidorova, V. N. Lebedev, A. A. Petrov, A. V. Ovchinnikov, I. V. Shatokhina, T. E. Sizikova, V. E. Sazonov, E. S. Mukhacheva, S. V. Borisevich   +10 more
doaj   +1 more source