Results 61 to 70 of about 291,218 (316)

Effects of Epstein–Barr virus infection on liver function in children

Journal of Infection and Public Health, 2020
Objective: In order to analyze the effect of Epstein–Barr (EB) virus infection on the liver function of children, the age and season of children susceptible to EB virus were analyzed in this study.
Yongju Zhang, Yuqi Zhao, Yajing Jiang, He Wang   +3 more
doaj   +1 more source

Respiratory Syncytial Virus Infection Induces Expression of Inducible Nitric Oxide Synthase, CD3, and CD8 in Naturally Occurring Pneumonia in Lambs

Acta Veterinaria, 2021
Respiratory syncytial virus (RSV) is an RNA virus that belongs to the Pneumovirus genus of the Paramyxoviridae family. The aim of this study was to evaluate the expressions of inducible nitric oxide synthetase (iNOS), CD3 (pan T cells), and CD8 ...
Yaman Turan, Aydemir Ceyhun
doaj   +1 more source

Immunohistochemical Evaluation of CD3, CD4, CD8, and CD20 in Decidual and Trophoblastic Tissue Specimens of Patients with Recurrent Pregnancy Loss

Clinics and Practice, 2022
Recurrent miscarriages affect up to 5% of couples. CD3+ (T-lymphocytes), CD4+ (helper T-lymphocytes), CD8+ (cytotoxic T-lymphocytes), and CD20+ (B-lymphocytes) cells may participate in the pathophysiology of recurrent pregnancy loss (RPL).
Dimitrios Kavvadas, Sofia Karachrysafi, Pinelopi Anastasiadou, Asimoula Kavvada, Stella Fotiadou, Angeliki Papachristodoulou, Theodora Papamitsou, Antonia Sioga   +7 more
doaj   +1 more source

Tumor-induced senescent T cells promote the secretion of pro-inflammatory cytokines and angiogenic factors by human monocytes/macrophages through a mechanism that involves Tim-3 and CD40L [PDF]

, 2014
Solid tumors are infiltrated by immune cells where macrophages and senescent T cells are highly represented. Within the tumor microenvironment, a cross-talk between the infiltrating cells may occur conditioning the characteristic of the in situ immune ...
Acosta Rodriguez, Eva Virginia, Canale, Fernando Pablo, Gastman, B, Gruppi, Adriana, Mena, Hebe Agustina, Montes, Carolina Lucia, Negrotto, Soledad, Ramello, María Cecilia, Tosello Boari, Jimena   +8 more
core   +2 more sources

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Case report: Granzyme-B expression by T- and B- cells during severe AQP4-positive Neuromyelitis Optica spectrum disorder with fatal venous thromboembolism outcome

Frontiers in Neurology, 2023
BackgroundThe expression of serine protease granzyme-B (GzmB) by circulating CD8+ T lymphocytes has been recently suggested as a biomarker for poor immunotherapy response and severe disability in patients with Neuromyelitis Optica spectrum disorders ...
Vinícius Oliveira Boldrini, Vinícius Oliveira Boldrini, Mariana Rabelo Brito, Raphael Patrício Silva Quintiliano, Lucas Scárdua Silva, Lucas Scárdua Silva, Clarissa Lin Yasuda, Clarissa Lin Yasuda, Fernando Cendes, Fernando Cendes, Alessandro Santos Farias, Alessandro Santos Farias, Alfredo Damasceno, Alfredo Damasceno   +13 more
doaj   +1 more source

Failure in generating hemopoietic stem cells is the primary cause of death from cytomegalovirus disease in the immunocompromised host [PDF]

, 1988
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that CMV infection interferes with the earliest detectable step in hemopoiesis, the generation of the stem cell CFU-S-I, and thereby prevents the ...
Busch, Friedrich W., Bühring, Hans-Jörg, Koszinowski, Ulrich H., Mutter, Wolfgang, Reddehase, Matthias J.   +4 more
core   +2 more sources

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Regional differences in the density of Langerhans cells, CD8-positive T lymphocytes and CD68-positive macrophages: a preliminary study using elderly donated cadavers [PDF]

Anatomy & Cell Biology, 2015
To provide a better understanding of the local immune system in the face and external genitalia, i.e., the oral floor, lower lip, palpebral conjunctiva, anus and penis, we examined the distribution and density of CD1a-positve Langerhans cells, CD8-positive suppressor T lymphocytes and CD68-positive macrophages using specimens from 8 male elderly ...
Omine, Yuya, Hinata, Nobuyuki, Yamamoto, Masahito, Kasahara, Masaaki, Matsunaga, Satoru, Murakami, Gen, Abe, Shin-ichi   +6 more
openaire   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source