Results 191 to 200 of about 729,582 (283)

Found in translation: the human equivalent of mouse CD8+ dendritic cells [PDF]

, 2010
José A. Villadangos, Ken Shortman
openalex   +1 more source

Honeysuckle‐Derived Nanovesicles Regulate Gut Microbiota for the Treatment of Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study explores honeysuckle‐derived nanovesicles (HNVs) for treating inflammatory bowel disease. Orally administered HNVs alleviates colitis in mice by repairing the gut barrier, reducing inflammation, and restoring a healthy gut microbiota.
Yuanyuan Wang, Yuanhao Zhou, Qingyuan Wu, Yishu Li, Yilin Huang, Kexin Yu, Ping Li, Zhenye Lv, Haotian Liu, Hai Zou, Huiyu Liu, Xiaozhou Mou   +11 more
wiley   +1 more source

CD40 agonist improves the therapeutic efficacy of irreversible electroporation ablation for metastatic melanoma by promoting unexpected CD8⁺CD103⁺ cDC1 and TRM cell responses. [PDF]

Cancer Immunol Immunother
Wu Z, Yang Z, Iftikhar T, Groot G, Leary SC, Baniak N, Ahmed S, Bosch M, Moser M, Zhang W, Jiang J, Xiang J.   +11 more
europepmc   +1 more source

Supplementary Figure 5 from Cytotoxic CD8⁺ T Cells Downregulate GPX4 to Promote Ferroptosis in Melanoma That Drives Antitumor Immunity

Karine Flem‐Karlsen, Ronan Talty, Meaghan K. McGeary, Koonam Park, Durga Thakral, Veronica T. Brooks, Andrew J. Daniels, William Damsky, Simon F. Roy, Goran Micevic, Marcus Bosenberg   +10 more
openalex   +1 more source

233. Fas+ CD4+ and Fas+ CD8+ cells from the peripheral blood of melanoma patients preferentially bind annexin V

, 2003
T Osawa, Agnieszka Kaczmarek, Dariusz Kowalczyk, M. Bogusz-Osawa, Andrzej Maćkiewicz   +4 more
openalex   +1 more source

ZFPL1 Promotes Colorectal Cancer Progression by Stabilizing ASS1 to Drive the Urea Cycle and M2 Macrophage‐Mediated Metastatic Colonization

Advanced Science, EarlyView.
ScRNA‐seq reveals ZFPL1‐specific enrichment in malignant CRC cells. Mechanistically, ZFPL1 stabilizes ASS1 by blocking K57 ubiquitination, activating urea cycle metabolism to drive progression. ZFPL1 inhibition reprograms the TME by suppressing M2 macrophages polarization and promotion M1 macrophages, thereby inhibiting CRC liver metastasis ...
Xiangjun Qian, Chenxi Xie, Beilin Zhang, Hengsong Cao, Zhengqing Lu, Li Liu, Shipeng Dai, Xiaoqian Wang, Xiaokai Zhang, Feng Han, Yanyan Liu, Haibo Yu, Weiwei Tang, Jinxue Zhou, Xiaopei Hao   +14 more
wiley   +1 more source

Figure S5 from Chronic ISG15 Exposure Accelerates CD8⁺ T-cell Dysfunction while Increasing PD-1 Blockade Sensitivity in Oral Squamous Cell Carcinoma

Yu-Lin Chen, Amir Yousif, Chung–Hsing Chen, Ava Lowin, Abbey A. Saadey, Ssu-Han Wang, Shih Sheng Jiang, Ya‐Wen Chen, Hazem E. Ghoneim   +8 more
openalex   +1 more source

Stimuli‐Responsive CuFeTe2 Nanosheets for Amplified Cuproptosis/Ferroptosis in Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Dual‐stimuli‐responsive CuFeTe2 nanosheets (CFT) induce cuproptosis/ferroptosis via TME‐responsive Fe2⁺/Cu2⁺ release and NIR‐II photothermal effects, amplifying ROS and depleting HSP70/ATP to trigger ICD and immune activation, while ensuring biocompatible renal clearance for TNBC therapy.
Molin Liu, Jian Zheng, Mengqi Yu, Qirui Wang, Yi Yuan, Nannan Shao, Xiaoliang Yang, Tianxi Shen, Li Wang, Aiyun Li, Rui Liu, Jimin Cao, Xi Liu, Fangfang Cao, Yanlin Feng   +14 more
wiley   +1 more source

Multimodal cell-cell communication driving CD8⁺ T cell dysfunction and immune evasion. [PDF]

Front Immunol
Chen L, Huang Q, Zhou P.
europepmc   +1 more source

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang, Sheyu Zhang, Lu Guo, Yichun Pan, Juan Huang, Yishuai Ji, Jiaqi Tao, Yong Wei, Xiaojia Wang, Qin Wu   +9 more
wiley   +1 more source