Results 191 to 200 of about 394,438 (273)

Paclitaxel/Luteolin Coloaded Dual‐Functional Liposomes for Esophageal Cancer Therapy

Advanced Science, EarlyView.
The authors develop a pH‐sensitive aptamer‐modified liposome (EA2‐PSL‐PTX/LUT) to illustrate a strategy for the precise delivery of combinational chemotherapeutic drugs for esophageal squamous cell carcinoma (ESCC) targeted therapy. EA2‐PSL‐PTX/LUT provides efficient co‐loading, tumor targeting, and controlled release of luteolin and paclitaxel ...
Congyong Sun, Fei Xie, Huiyun Zhang, Lulu Feng, Yuting Wang, Chaofan Huang, Zhizhen Cui, Chao Luo, Li Zhang, Qilong Wang   +9 more
wiley   +1 more source

Impact of rosuvastatin on the memory potential and functionality of CD8⁺ T cells from people with HIV. [PDF]

EBioMedicine
Perdomo-Celis F, Passaes C, Monceaux V, Lambotte O, Costagliola D, Chevalier MF, Weiss L, Sáez-Cirión A.   +7 more
europepmc   +1 more source

A monoclonal antibody reactive with a 15-kDa cytoplasmic granule-associated protein defines a subpopulation of CD8+ T lymphocytes. [PDF]

, 1990
Paul Anderson, Cathryn Nagler‐Anderson, Carmeline O’Brien, Herbert Levine, Simon C. Watkins, Henry S. Slayter, M L Blue, Stuart F. Schlossman   +7 more
openalex   +1 more source

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

Advanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni, Jian Tan, Julen Reyes, Alistair M Senior, Caitlin Andrews, Jemma Taitz, Camille Potier‐Villette, Claire Wishart, Alanna Spiteri, Laura Piccio, Nicholas Jonathan Cole King, Romain Barrès, David Raubenheimer, Stephen James Simpson, Ralph Nanan, Laurence Macia   +15 more
wiley   +1 more source

Deficiency in infiltration of CD8/CD3 positive lymphocytes and macrophages plays a role in lip carcinogenesis: an immunohistochemical study

Brazilian Journal of Otorhinolaryngology
Objective: To evaluate the immunoexpression profile for CD8, CD3, CD20 and CD68 in the process and carcinogenesis of Carcinoma of the vermilion lip. Methods: Average cell count with positive expression for CD3, CD8, CD20 and CD68.
Iana Aragão Magalhães, Gabriella Alves Juliao Costa, Marcela Maria Fontes Borges, Anna Clara Aragão Matos Carlos, Karine Cestaro Mesquita, Larissa Mont´Alverne de Arruda, Maria do Perpétuo Socorro Saldanha Cunha, Fabrício Bitu Sousa, Paulo Goberlânio de Barros Silva   +8 more
doaj  

Landscape of T Cells in Tuberculous Pleural Effusion. [PDF]

Clin Respir J
Zou L, Chen J, Xie L, Zhang L, Wan L, Li W, Xu H.   +6 more
europepmc   +1 more source

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

Advanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang, Qixia Xu, Zhirui Jiang, Rong Sun, Qun Wang, Sanhong Liu, Xin Luan, Judith Campisi, James L. Kirkland, Weidong Zhang, Yu Sun   +10 more
wiley   +1 more source

Memory-promoting function of miR-379-5p attenuates CD8⁺ T cell exhaustion by targeting immune checkpoints. [PDF]

J Immunother Cancer
Lin YZ, Liu CH, Wu WR, Liao TY, Lee CC, Li HW, Chung FC, Shen YC, Zhuo GY, Liu LC, Cheng WC, Wang SC.   +11 more
europepmc   +1 more source

CD8+ T cells can be primed in vitro to produce IL-4. [PDF]

, 1992
Robert A. Seder, Jean‐Louis Boulay, F D Finkelman, Sandrine Barbier, Shlomo Z. Ben‐Sasson, Graham Le Gros, W E Paul   +6 more
openalex   +1 more source

Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer

Advanced Science, EarlyView.
A single‐cell and spatial transcriptional atlas reveals the architecture of human gastric cancer stem cell (CSC) niche and the developmental trajectory of CSCs. These CSCs interact with immunosuppressive immune cells thereby constructing immune‐suppressive niche, and inflammatory cancer‐associated fibroblast (iCAFs) to enhance stemness through ...
Guangyu Zhang, Xin Zhang, Wenting Pan, Xizhao Chen, Lingfei Wan, Chunjie Liu, Yuting Yong, Yue Zhao, Shuli Sang, Lihua Zhang, Sheng Yao, Yushu Guo, Mingmei Wang, Xinhui Wang, Guangdun Peng, Xinlong Yan, Yanchun Wang, Min Zhang   +17 more
wiley   +1 more source