Results 201 to 210 of about 394,438 (273)

Phenotypic and functional dysregulations of CD8 + T Cells in myasthenia gravis. [PDF]

Clin Exp Med
Liu C, Zhang H, Zhai YY, Dong J, Zhou Y, Li H, Zhang M, Yang CL, Zhang P, Li XL, Duan RS, Du T.   +11 more
europepmc   +1 more source

THE ROLE OF CD8+ AND CD4+ CELLS IN ISLET ALLOGRAFT REJECTION

, 1990
Hitoshi Yamamoto, Morito Monden, Minoru Kawai, Akiko Uenaka, Mitsukazu Gotoh, Takesada Mori, Masami Sakurai, Hiroshi Shiku, Eiichi Nakayama   +8 more
openalex   +1 more source

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Advanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang, Lin Li, Yuchen Ge, Anni Chen, Shanchao Diao, Yueling Yang, Qianyue Chen, Yingling Zhou, Jie Shao, Fanyan Meng, Lixia Yu, Manman Tian, Xiaoping Qian, Zhaoyu Lin, Chen Xie, Baorui Liu, Rutian Li   +16 more
wiley   +1 more source

Prognostic impact and landscape of cellular CXCR5 chemokine receptor expression in clear-cell renal cell carcinoma. [PDF]

Cancer Immunol Immunother
Arai M, Tanaka N, Takamatsu K, Murakami T, Mikami S, Imamura T, Nakamura K, Nishihara H, Oya M.   +8 more
europepmc   +1 more source

CD11b (Mac-1): a marker for CD8+ cytotoxic T cell activation and memory in virus infection. [PDF]

, 1992
H. McFarland, Sharon Nahill, Joseph W. Maciaszek, Raymond M. Welsh   +3 more
openalex   +1 more source

PPY‐Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma features abundant stromal components that hinder therapy efficacy. Single‐cell RNA sequencing analysis combined with experiments identified PPY, a gastrointestinal hormone, as a novel inducer of immunosuppressive iCAFs. Mechanistic studies revealed that PPY activates the non‐canonical NF‐κB pathway via EGFR.
Mengdie Cao, Wang Peng, Bin Cheng, Ronghua Wang, Wei Chen, Luyao Liu, Hai Huang, Shiru Chen, Haochen Cui, JingWen Liang, Qiaodan Zhou, Si Xiong, Shuya Bai, Luoxia Liu, Yuchong Zhao   +14 more
wiley   +1 more source

Single-cell transcriptional responses of T cells during microsporidia infection. [PDF]

Commun Biol
Tang Y, Cao L, Jin J, Li T, Chen Y, Lu Y, Li T, Weiss LM, Pan G, Bao J, Zhou Z.   +10 more
europepmc   +1 more source

Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CD8+ CTL in vivo with peptide vaccine constructs. [PDF]

, 1994
Mutsunori Shirai, C D Pendleton, J Ahlers, Toshiyuki Takeshita, Mark J. Newman, Jay A. Berzofsky   +5 more
openalex   +1 more source

Extracellular Vesicle‐Packaged Linc‐ZNF25‐1 from Pancreatic Cancer Cell Promotes Pancreatic Stellate Cell Uptake of Asparagine to Advance Chemoresistance

Advanced Science, EarlyView.
This study explores the role of gemcitabine (GEM)‐resistant pancreatic cancer‐derived extracellular vesicles (EVs) in activating pancreatic stellate cells (PSCs) and promoting extracellular matrix production. GEM‐resistant cells release higher levels of asparagine (Asn), which triggers PSC activation. Long noncoding RNA sequencing identified linc‐ZNF25‐
Miao Yu, Mingxin Su, Zhenfeng Tian, Lele Pan, Zongmeng Li, Enlai Huang, Yinting Chen   +6 more
wiley   +1 more source

Exploring the possible mechanism of low-dose naloxone exposure improving the immune microenvironment of gastric cancer tumors. [PDF]

Front Immunol
Min X, Ma Y, Lv M, Li X, Lv R, Zhao X, Leng Y.   +6 more
europepmc   +1 more source