Results 201 to 210 of about 419,552 (297)

Role for CD8+ T cells in antichlamydial immunity defined by Chlamydia-specific T-lymphocyte clones [PDF]

, 1994
Joseph U. Igietseme, D M Magee, David M. Williams, Roger G. Rank   +3 more
openalex   +1 more source

PD-L1(+) tumor-associated macrophages induce CD8(+) T Cell exhaustion in hepatocellular carcinoma. [PDF]

Neoplasia
Nosaka T, Ohtani M, Yamashita J, Murata Y, Akazawa Y, Tanaka T, Takahashi K, Naito T, Imamura Y, Koneri K, Goi T, Nakamoto Y.   +11 more
europepmc   +1 more source

A Peripheral Mechanism of Depression: Disturbed Intestinal Epithelial Per2 Gene Expression Causes Depressive Behaviors in Mice with Circadian Rhythm Disruption via Gut Barrier Damage and Microbiota Dysbiosis

Advanced Science, EarlyView.
Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang, Xuan Qin, Haiyue Song, Jieru Zhou, Hui Wei, Lun Zhang, Yi Liu, Zhuoqun Wang, Yiren Zhang, Yiwen Lai, Jiayu Yang, Wenting Hu, Zhongshan Chen, Ji Zeng, Yu Jin, Xiaochuan Wang, Rong Liu   +16 more
wiley   +1 more source

CD8+ cytotoxic T lymphocytes against antigenic variants of caprine arthritis-encephalitis virus

, 1993
Carol A. Lichtensteiger, William P. Cheevers, William C. Davis   +2 more
openalex   +1 more source

CD4+ and CD8+ T-cell-dependent and -independent host defense mechanisms can operate to control and resolve primary and secondary Francisella tularensis LVS infection in mice [PDF]

, 1994
J. Wayne Conlan, Anders Sjöstedt, R J North   +2 more
openalex   +1 more source

Age-Stratified Immune-Inflammatory Profiles and Prognostic Implications of Old Patients in the ICU: A Prospective Study. [PDF]

J Inflamm Res
Lian H, Wang G, Zhang Q, Zhao H, Wang X.
europepmc   +1 more source

PVC Nanoplastics Exposure Exacerbates Asthma through R‐Loop Accumulation and Subsequent STING Activation in Macrophages

Advanced Science, EarlyView.
Polyvinyl chloride (PVC) nanoplastics (NPs) are shown to aggravate allergic airway inflammation in asthma by triggering R‐loop accumulation and activating the cGAS‐STING pathway in macrophages. This study reveals a novel immunotoxic mechanism linking environmental plastic exposure to asthma pathogenesis and highlights potential molecular targets for ...
Qimei Bao, Yixing Huang, Mingcong Deng, Chunkai Zhang, Dan Zu, Hanyi He, Yangchan Hu, Yuke Zhong, Chen Liang, Haidong Liu, Wumin Dai, Yanhua He, Yaoshu Teng, Ji Jing, Yin Shi, Xiangdong Cheng, Zu Ye   +16 more
wiley   +1 more source

Specific lysis of human immunodeficiency virus type 1-infected cells by a HLA-A3.1-restricted CD8+ cytotoxic T-lymphocyte clone that recognizes a conserved peptide sequence within the gp41 subunit of the envelope protein. [PDF]

, 1991
Kenichi Takahashi, Licheng Dai, Thomas R. Fuerst, William E. Biddison, Patricia L. Earl, Bernard Moss, Francis A. Ennis   +6 more
openalex   +1 more source

CD8⁺HLA-DR⁺CD27⁺ T cells define a population of naturally occurring regulatory precursors in humans. [PDF]

Sci Adv
Guo H, Wang B, Wu Z, Zhang Q, Jiang X, Zhang F, Zhou J, Fan S, Zhou Y, Xu ZL, Wang Y, Zhao XY, Huang XJ.   +12 more
europepmc   +1 more source

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

Advanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin, Xiaofan Xiong, Yan Zhang, Siyu Zhang, Shuting Zhang, Yu Yang, Yingxue Liang, Lulu Zang, Xi Chen, Wenjuan Li, Issam Halalmeh, Rui Zhou, Zongfang Li, Haowen Liu, Jing Geng   +14 more
wiley   +1 more source