Results 21 to 30 of about 419,552 (297)
OncoImmunology, 2021 OX40 (CD134) is a co-stimulatory molecule mostly expressed on activated T lymphocytes. Previous reports have shown that OX40 can be an immuno-oncology target and a clinical biomarker for cancers of various organs.
Hiroshi Yokouchi +23 more
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Contrasted TCRβ Diversity of CD8+ and CD8− T Cells in Rainbow Trout
PLoS ONE, 2013 Teleost fish express highly diverse naive TCRβ (TRB) repertoires and mount strong public and private clonal responses upon infection with pathogens. Fish T cells express typical markers such as CD8, CD4-1 and CD4-2, CD3, CD28 and CTLA4. Fish CD8(+) T cells have been shown to be responsible for antigen-specific cell-mediated cytotoxicity in in vitro ...
Castro, Dona Maria Rosario +9 more
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OncoImmunology, 2017 The French phase 3 trial (OS 2006) testing zoledronic acid, an osteoclast inhibitor, with chemotherapy and surgery did not improve the outcome of patients with osteosarcoma (OS).
Anne Gomez-Brouchet +19 more
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Schopenhauer and I. Kant in A. A. Fet’s philosophical and political worldview (conclusion) [PDF]
Кантовский сборник, 2013 The concluding part of the work focuses on the independence of A. A. Fet’s philosophical worldview strongly emphasised by the poet himself and his close friends. Although he quotes Schopenhauer and Kant, he criticised them and demonstrates an independent
Kalinnikov L.
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CD8 is required during positive selection of CD4-/CD8+ T cells. [PDF]
The Journal of experimental medicine, 1990 Interactions between self-MHC molecules and T cells are necessary for the proper development of mature T cells, in part due to an absolute requirement for self-MHC-TCR interactions. Recently, we showed that CD4-mediated interactions also participate in shaping the T cell repertoire during thymic maturation.
Juan Carlos Zúñiga-Pflücker +3 more
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Инфекция и иммунитет, 2017 Infectious mononucleosis is a widespread disease caused by certain members of Herpesviridae family. Acute infectious mononucleosis develops predominantly in children and is accompanied by an increase of the number of circulating naive CD4+ and naive CD8+
E. N. Filatova +4 more
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KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans
Cell Reports, 2023 Summary: Subsets of the human CD8+ T cell population express inhibitory NK cell receptors, such as killer immunoglobulin-like receptors (KIRs) and NKG2A.
Seong Jin Choi +7 more
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Precommitment of CD4+CD8+ thymocytes to either CD4 or CD8 lineages. [PDF]
Proceedings of the National Academy of Sciences, 1993 CD4+ and CD8+ mature T cells arise from CD4+CD8+ precursors in the thymus. During this process, cells expressing T-cell receptors (TCRs) reactive with self major histocompatibility complex (MHC) class I or II molecules are positively selected to the CD8 or CD4 lineage, respectively.
Crompton, Tessa +3 more
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Epithelial-to-mesenchymal transition and its association with PD-L1 and CD8 in thyroid cancer
Endocrine Connections, 2020 Programmed cell death-ligand 1 (PD-L1) has recently been shown to play a role in the regulation of epithelial-to-mesenchymal transition (EMT); however, the relationship between PD-L1 expression, EMT and the inflammatory tumour microenvironment has yet to
Marra Jai Aghajani +7 more
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OncoImmunology, 2020 After neoadjuvant chemoradiotherapy for esophageal adenocarcinoma, up to 29% of patients have a pathological complete response (pCR). What to do afterward is still under debate.
Andromachi Kotsafti +12 more
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