Improved induction of anti-melanoma T cells by adenovirus-5/3 fiber modification to target human DCs [PDF]
, 2018 To mount a strong anti-tumor immune response, non T cell inflamed (cold) tumors may require combination treatment encompassing vaccine strategies preceding checkpoint inhibition.
Chondronasiou, Dafni +9 more
core +11 more sources
Инфекция и иммунитет, 2017 Infectious mononucleosis is a widespread disease caused by certain members of Herpesviridae family. Acute infectious mononucleosis develops predominantly in children and is accompanied by an increase of the number of circulating naive CD4+ and naive CD8+
E. N. Filatova +4 more
doaj +1 more source
Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in Human Immunodeficiency Virus Type 1 infection [PDF]
, 2004 Numerous studies now support that human immunodeficiency virus type 1 (HIV-1) evolution is influenced by immune selection pressure, with population studies showing an association between specific HLA alleles and mutations within defined cytotoxic T ...
Allen, T.M. +19 more
core +2 more sources
Schopenhauer and I. Kant in A. A. Fet’s philosophical and political worldview (conclusion) [PDF]
Кантовский сборник, 2013 The concluding part of the work focuses on the independence of A. A. Fet’s philosophical worldview strongly emphasised by the poet himself and his close friends. Although he quotes Schopenhauer and Kant, he criticised them and demonstrates an independent
Kalinnikov L.
doaj +1 more source
KIR+CD8+ and NKG2A+CD8+ T cells are distinct innate-like populations in humans
Cell Reports, 2023 Summary: Subsets of the human CD8+ T cell population express inhibitory NK cell receptors, such as killer immunoglobulin-like receptors (KIRs) and NKG2A.
Seong Jin Choi +7 more
doaj +1 more source
Early Skewed Distribution of Total and HIV-Specific CD8+ T-Cell Memory Phenotypes during Primary HIV Infection Is Related to Reduced Antiviral Activity and Faster Disease Progression [PDF]
, 2014 The important role of the CD8+ T-cells on HIV control is well established. However, correlates of immune protection remain elusive. Although the importance of CD8+ T-cell specificity and functionality in virus control has been underscored, further ...
Cahn, Pedro +10 more
core +1 more source
Epithelial-to-mesenchymal transition and its association with PD-L1 and CD8 in thyroid cancer
Endocrine Connections, 2020 Programmed cell death-ligand 1 (PD-L1) has recently been shown to play a role in the regulation of epithelial-to-mesenchymal transition (EMT); however, the relationship between PD-L1 expression, EMT and the inflammatory tumour microenvironment has yet to
Marra Jai Aghajani +7 more
doaj +1 more source
Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. [PDF]
, 2017 The gastrointestinal mucosa is an important site of HIV acquisition, viral replication, and pathogenesis. Immune cells in mucosal tissues frequently differ in phenotype and function from their non-mucosal counterparts.
Critchfield, JW +7 more
core +1 more source
Immunological Changes after Cancer Treatment and Participation in an Exercise Program [PDF]
, 2003 Purpose: The purpose of this investigation was to evaluate the impact of undertaking peripheral blood stem cell transplantation (PBST) on T-cell number and function, and to determine the role of a mixed type, moderate intensity exercise program in ...
Andrykowski +27 more
core +2 more sources
OncoImmunology, 2020 After neoadjuvant chemoradiotherapy for esophageal adenocarcinoma, up to 29% of patients have a pathological complete response (pCR). What to do afterward is still under debate.
Andromachi Kotsafti +12 more
doaj +1 more source