Results 71 to 80 of about 15,671 (193)

Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers [PDF]

, 2021
Nucleated teleost red blood cells (RBCs) are known to express molecules from the major histocompatibility complex and peptide-generating processes such as autophagy and proteasomes, but the role of RBCs in antigen presentation of viruses have not been ...
Ciordia, Sergio, Pérez, Luis, Puente Marín, Sara, Coll Morales, Julio, Ortega-Villaizan Romo, María del Mar, Requena Platek, Ricardo, Mena, María Carmen, CHICO GRAS, VERONICA, Mercado, Luis, Nombela Díaz, Iván, Morales Lange, Byron   +10 more
core  

Metabolic Regulation of Macrophages in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang, Yu Zhang, Jiali Min, Jiahui Yang, Yuchen Li, Hao Zhang, Shanshan Liu   +6 more
wiley   +1 more source

Einfluss des HuR-Liganden APRIL auf die CD83 Expression [PDF]

, 2007
Dendritic cells (DC) are the most potent antigen presenting cells (APC) of the immune system and are able to sensitize even naive T cells. Mature DC are characterized by the expression of CD83, a surface molecule that is proposed to be involved in ...
Fries, Barbara
core   +1 more source

Transdifferentiation of neutrophils facilitates the establishment of infection by Leishmania donovani parasites

Infection and Immunity
Neutrophil transdifferentiation involves the acquisition of dendritic cell-like properties, challenging the traditional view of neutrophils being solely phagocytes. The presence of transdifferentiated neutrophils is established in Visceral Leishmaniasis,
Madhurima Roy, Aniruddha Bagchi, Chaitali Karmakar, Mitali Chatterjee   +3 more
doaj   +1 more source

Inflammatory cell expression of Toll-like receptor-2 (TLR2) within refractory periapical granuloma. [version 1; referees: 2 approved]

F1000Research, 2018
Background: Toll-like receptor-2 (TLR2) is highly important within the immune system. Characterization of the expression of TLR2 within inflammatory cells in periapical lesions could help in diagnosis and management of refractory cases.
Eric Chen, Mahmoud M. Bakr, Norman Firth, Robert M. Love   +3 more
doaj   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, Volume 269, Issue 4-5, Page 387-398, August 2026.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

Eliminating PD‐L1 on Dendritic Cell Extracellular Vesicles for Immunotherapy Potentiates Immune‐Mediated Tumour Rejection in Mice

Journal of Extracellular Vesicles, Volume 15, Issue 7, July 2026.
Extracellular vesicles (EVs) for immune therapy of cancer have both direct and indirect effects on immune cells. When taken up, the loaded antigen is presented by the host's dendritic cells (indirect). In this case, EV surface molecules like MHC‐peptide complexes on EVs are of minor importance. Here we show that removal of PD‐L1 from the surface of EVs
Loes Teeuwen, Loïc Steiner, Chantal Reinhardt, Annemarijn Offens, Jesse E. Kuipers, Daniel Martínez‐Martínez, Jules Mazouin, Benedict J. Chambers, Gözde Güçlüler Akpinar, Susanne Gabrielsson   +9 more
wiley   +1 more source

Neutrophils in Atlantic salmon (Salmo salar L.) are MHC class II+ and secret IL-12p40 upon bacterial exposure

Aquaculture and Fisheries
Antigen-presentation via major histocompatibility complex (MHC) to T cells is the key event to initiate adaptive immune responses. In teleosts, as in mammals, the main types of professional antigen-presenting cells (APCs) are dendritic cells (DCs ...
Gyri Teien Haugland, Anita Rønneseth, Lene Gundersen, Harald Sæbø Lunde, Kaja Nordland, Heidrun Inger Wergeland   +5 more
doaj   +1 more source

Efficient Maturation and Cytokine Production of Neonatal DCs Requires Combined Proinflammatory Signals

Clinical and Developmental Immunology, 2005
Specific functional properties of dendritic cells (DCs) have been suspected as being responsible for the impaired specific immune responses observed in human neonates.
Doreen Krumbiegel, Jan Rohr, Peter Schmidtke, Markus Knuf, Fred Zepp, Claudius U. Meyer   +5 more
doaj   +1 more source

Dendritic cells matured with recombinant human sperm associated antigen 9 (rhSPAG9) induce CD4+, CD8+ T cells and activate NK cells: a potential candidate molecule for immunotherapy in cervical cancer

Cancer Cell International, 2021
Background Dendritic cell (DC)-based immunotherapy is capable of activating the immune system and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the tumor.
Hemavathi Dhandapani, Hascitha Jayakumar, Abirami Seetharaman, Shirley Sunder Singh, Selvaluxmy Ganeshrajah, Nirmala Jagadish, Anil Suri, Rajkumar Thangarajan, Priya Ramanathan   +8 more
doaj   +1 more source