Results 61 to 70 of about 448,583 (189)

CD83 positive dendritic cells are present in occasional perivascular cuffs in multiple sclerosis leasions

, 2003
Multiple sclerosis (MS) has a wide spectrum of clinical courses, characterized by multifocal central nervous system (CNS) damage, postulated to be mediated by CNS antigen-specific T cells.
M A Armstrong, S McQuaid, M Mirakhur, Plumb, J., Duddy, M., McQuaid, Stephen, Mirakhur, Meenakshi, J Plumb, M Duddy, Mirakhur, M., Armstrong, Marilyn, Armstrong, M. A., McQuaid, S   +12 more
core   +1 more source

Decrease in Circulating Dendritic Cell Precursors in Patients with Peripheral Artery Disease

Mediators of Inflammation, 2015
Peripheral artery disease (PAD) is a common manifestation of atherosclerosis. Inflammation is important for initiation and progression of the disease.
Daniel Kretzschmar, Ilonka Rohm, Sebastian Schäller, Stefan Betge, Rudin Pistulli, Yevgeniya Atiskova, Hans-R. Figulla, Atilla Yilmaz   +7 more
doaj   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, Volume 13, Issue 59, 23 October 2026.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

Annals of Neurology, Volume 100, Issue 4, Page 808-823, October 2026.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello, Mario Picozza, Gisella Guerrera, Silvia Corbisiero, Andrea Misiti, Roberta C. Placido, Alice Verdiani, Lorenzo de Marco, Manolo Sambucci, Elena Olivieri, Daniela F. Angelini, Esmeralda Quartuccio, Luca Prosperini, Carla Tortorella, Maria C. Buscarinu, Valeria Zancan, Francesca de Masi, Marco Salvetti, Claudio Gasperini, Giovanna Borsellino, Luca Battistini   +20 more
wiley   +1 more source

Ubiquitin ligase MARCH 8 cooperates with CD83 to control surface MHC II expression in thymic epithelium and CD4 T cell selection [PDF]

, 2016
Major histocompatibility complex class II (MHC II) expression is tightly regulated, being subjected to cell type-specific mechanisms that closely control its levels at the cell surface.
Justine D. Mintern, Gray, DH, Reema Jain, Jose A. Villadangos, Haiyin Liu, Jain, R, Vivian Vuong, Daniel H. Gray, Guan, J, Satoshi Ishido, Liu, H, Villadangos, JA, La Gruta, NL, Mintern, JD, Jing Guan, Vuong, V, Nicole L. La Gruta, Ishido, S   +17 more
core   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, Volume 6, Issue 10, October 2026.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Rainbow Trout Red Blood Cells Exposed to Viral Hemorrhagic Septicemia Virus Up-Regulate Antigen-Processing Mechanisms and MHC I&II, CD86, and CD83 Antigen-presenting Cell Markers [PDF]

, 2021
Nucleated teleost red blood cells (RBCs) are known to express molecules from the major histocompatibility complex and peptide-generating processes such as autophagy and proteasomes, but the role of RBCs in antigen presentation of viruses have not been ...
Ciordia, Sergio, Pérez, Luis, Puente Marín, Sara, Coll Morales, Julio, Ortega-Villaizan Romo, María del Mar, Requena Platek, Ricardo, Mena, María Carmen, CHICO GRAS, VERONICA, Mercado, Luis, Nombela Díaz, Iván, Morales Lange, Byron   +10 more
core   +1 more source

Closing the system: production of viral antigen-presenting dendritic cells eliciting specific CD8+ T cell activation in fluorinated ethylene propylene cell culture bags

Journal of Translational Medicine, 2020
Background A major obstacle to anti-viral and -tumor cell vaccination and T cell immunotherapy is the ability to produce dendritic cells (DCs) in a suitable clinical setting.
Jean-Philippe Bastien, Natalie Fekete, Ariane V. Beland, Marie-Paule Lachambre, Veronique Laforte, David Juncker, Vibhuti Dave, Denis-Claude Roy, Corinne A. Hoesli   +8 more
doaj   +1 more source

Single‐cell multi‐omics characterises transcriptional and chromatin accessibility heterogeneity of immune cells in allergic rhinitis

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
Key Points 1. SAR and PAR showed distinct immune landscapes. 2. Macro_CCL3 showed phenotype‐specific inflammatory and antigen‐presentation features. 3. CD8_Trm displayed subtype‐associated chromatin accessibility linked to cytotoxicity‐related signatures. 4.
Yisha Wu, Zhihan Xu, Shikai Han, Zhongzhen Liu, Rui Dong, Chuanyu Liu, Jianhua Yin, Jinmei Xue   +7 more
wiley   +1 more source

Transdifferentiation of neutrophils facilitates the establishment of infection by Leishmania donovani parasites

Infection and Immunity
Neutrophil transdifferentiation involves the acquisition of dendritic cell-like properties, challenging the traditional view of neutrophils being solely phagocytes. The presence of transdifferentiated neutrophils is established in Visceral Leishmaniasis,
Madhurima Roy, Aniruddha Bagchi, Chaitali Karmakar, Mitali Chatterjee   +3 more
doaj   +1 more source