Results 41 to 50 of about 448,583 (189)

The effect of Propionibacterium acnes on maturation of dendritic cells derived from acne patients' peripherial blood mononuclear cells.

Folia Histochemica et Cytobiologica, 2009
Propionibacterium acnes (P. acnes) has been implicated in the pathogenesis of acne vulgaris which is the most common cutaneous disorder. It has a proinflammatory activity and takes part in immune reactions modulating the Th1/Th2 cellular response.
Maria Juszkiewicz-Borowiec, Alina Olender, Jacek Tabarkiewicz, Anna Michalak-Stoma, Filip Stoma, Aldona Pietrzak, Piotr Pozarowski, Małgorzata Bartkowiak-Emeryk   +7 more
doaj   +1 more source

Human Bone Marrow Mesenchymal Stromal/Stem Cells Regulate the Proinflammatory Response of Monocytes and Myeloid Dendritic Cells from Patients with Rheumatoid Arthritis

Pharmaceutics, 2022
Rheumatoid arthritis (RA) is a disabling autoimmune disease whose treatment is ineffective for one-third of patients. Thus, the immunomodulatory potential of mesenchymal stromal/stem cells (MSCs) makes MSC-based therapy a promising approach to RA.
Paula Laranjeira, Mónia Pedrosa, Cátia Duarte, Susana Pedreiro, Brígida Antunes, Tânia Ribeiro, Francisco dos Santos, António Martinho, Margarida Fardilha, M. Rosário Domingues, Manuel Abecasis, José António Pereira da Silva, Artur Paiva   +12 more
doaj   +1 more source

Targeting CD83 for the treatment of graft-versus-host disease

, 2013
Graft-versus-host disease (GVHD) is a common and often fatal complication of bone marrow transplantation. Antigen-presenting cells from donor and recipient play a critical role in the initiation and maintenance of GVHD.
Wang, Xiongfei, Liu, Xiaosong, MING Q. WEI, XIAOSONG LIU, Wei, Ming Q, XIONGFEI WANG   +5 more
core   +1 more source

Environmentally weathered polystyrene particles induce phenotypical and functional maturation of human monocyte-derived dendritic cells

Journal of Immunotoxicology, 2022
Micro- and nanoplastics (MNP) are ubiquitously present in the environment due to their high persistence and bioaccumulative properties. Humans get exposed to MNP via various routes and consequently, they will encounter dendritic cells (DC) which are ...
Annemijne E. T. van den Berg, Maud Plantinga, Dick Vethaak, Kas J. Adriaans, Marianne Bol-Schoenmakers, Juliette Legler, Joost J. Smit, Raymond H. H. Pieters   +7 more
doaj   +1 more source

The relation of the frequency and functional molecules expression on plasmacytoid dendritic cells to postpartum hepatitis in women with HBeAg-positive chronic hepatitis B virus infection

Frontiers in Immunology, 2022
ObjectiveTo explore the correlation between postpartum hepatitis and changes of plasmacytoid dendritic cells’ (pDC) function and frequency in hepatitis B e antigen (HBeAg)-positive pregnant women with chronic hepatitis B virus (HBV) infection ...
Fuchuan Wang, Meiying Song, Yuhong Hu, Liu Yang, Xiaoyue Bi, Yanjie Lin, Tingting Jiang, Wen Deng, Shiyu Wang, Fangfang Sun, Zhan Zeng, Yao Lu, Ge Shen, Ruyu Liu, Min Chang, Shuling Wu, Yuanjiao Gao, Hongxiao Hao, Mengjiao Xu, Xiaoxue Chen, Leiping Hu, Gang Wan, Lu Zhang, Minghui Li, Minghui Li, Yao Xie, Yao Xie   +26 more
doaj   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

Advanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao, Lijuan Song, Meiqian Xu, Tianhao Liang, Yixuan Chen, Gui Chen, Zaihuan Lin, Huakang Du, Guofei Feng, Zhiming Feng, Qi Zhang, Fan Pan, Saixuan Yang, Xinyin Zhang, Wenxu Peng, Tianlong Li, Zhuoshen Lin, Yabang Chen, Jiayi Liu, Baoxin Peng, Yan Liu, Xing Niu, Ting Li, Chengyu Huang, Ke Mo, Jianlei Xie, Yu Zou, Xiaowen Zhang   +27 more
wiley   +1 more source

Anti-CD83 promotes IgG1 isotype switch in marginal zone B cells in response to TI-2 antigen

Immunobiology, 2015
CD83 is a transmembrane glycoprotein that is rapidly up-regulated on activated B cells. Although CD83 itself is incapable to transduce intracellular signaling, it acts as a negative regulator of B cell function. We have recently described that a single application of anti-CD83 antibody results in dramatically enhanced production of antigen-specific ...
Birte, Kretschmer, Jan, Weber, Andreas, Hutloff, Bernhard, Fleischer, Minka, Breloer, Anke, Osterloh   +5 more
openaire   +2 more sources

Langerin-expressing and CD83-expressing cells in oral lichen planus lesions

, 2007
OBJECTIVE: Dendritic Langerhans cells (LCs) have been attributed a role in the pathogenesis of lichen planus as autoantigen-presenting cells initiating expansion of autoreactive T cells.
Zellin, Göran,, Jenny Gustafson, Christina Eklund, Gustafson, Jenny,, Göran Zellin, Magnusson, Bengt,, Bengt Hasséus, Wallström, Mats,, Bengt Magnusson, Hasséus, Bengt,, Mats Wallström, Eklund, Christina,   +11 more
core   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Re-expression of CD14 in Response to a Combined IL-10/TLR Stimulus Defines Monocyte-Derived Cells With an Immunoregulatory Phenotype

Frontiers in Immunology, 2019
Interleukin 10 is a central regulator of the antigen-presenting function of myeloid cells. It exerts immunomodulatory effects in vivo and induces a regulatory phenotype in monocyte-derived cells in vitro.
Sören Krakow, Marie L. Crescimone, Charlotte Bartels, Verena Wiegering, Matthias Eyrich, Paul G. Schlegel, Matthias Wölfl   +6 more
doaj   +1 more source