Results 21 to 30 of about 15,671 (193)

Soluble CD83 alleviates experimental allergic rhinitis through modulating antigen-specific Th2 cell property [PDF]

International Journal of Biological Sciences, 2020
Background and aims: Dysfunction of the immune regulatory system plays a role in the pathogenesis of allergic rhinitis (AR). The underlying mechanism needs to be further investigated. Published data indicate that soluble CD83 (sCD83) has immune regulatory activities. This study aims to investigate the role of sCD83 in the alleviation of experimental AR.
Wu, Yong-Jin, Song, Yan-Nan, Geng, Xiao-Rui, Ma, Fei, Mo, Li-Hua, Zhang, Xiao-Wen, Liu, Da-Bo, Liu, Zhi-Gang, Yang, Ping-Chang   +8 more
openaire   +2 more sources

CD83 antigen expression and its role in the progression of systemic malignancies. [PDF]

Sao Paulo Med J, 2013
Kapoor S.
europepmc   +3 more sources

DataSheet_1_Anti-Mouse CD83 Monoclonal Antibody Targeting Mature Dendritic Cells Provides Protection Against Collagen Induced Arthritis.pdf [PDF]

, 2022
Antibodies targeting the activation marker CD83 can achieve immune suppression by targeting antigen-presenting mature dendritic cells (DC). This study investigated the immunosuppressive mechanisms of anti-CD83 antibody treatment in mice and tested its ...
Wei-Hsun Hsu (12067661), Hsiao-Ting Chen (6725804), Tsun-Ho Lo (6689747), Helen Roberts (446195), Xinsheng Ju (12067664), Georgina J. Clark (6689777), Adelina Romano (12067658), Pablo A. Silveira (6689774), Fiona Kupresanin (41638), Daniel G. Baker (12067667)   +9 more
core   +1 more source

Identification of dendritic cell precursor from the CD11c+ cells expressing high levels of MHC class II molecules in the culture of bone marrow with FLT3 ligand

Frontiers in Immunology, 2023
Dendritic cells (DCs) are readily generated from the culture of mouse bone marrow (BM) treated with either granulocyte macrophage-colony stimulating factor (GM-CSF) or FMS-like tyrosine kinase 3 ligand (FLT3L).
Hyunju In, Hyunju In, Ji Soo Park, Ji Soo Park, Hyun Soo Shin, Hyun Soo Shin, Seul Hye Ryu, Seul Hye Ryu, Seul Hye Ryu, Moah Sohn, Moah Sohn, Wanho Choi, Wanho Choi, Sejung Park, Sejung Park, Soomin Hwang, Soomin Hwang, Jeyun Park, Lihua Che, Lihua Che, Tae-Gyun Kim, Min Kyung Chu, Hye Young Na, Hye Young Na, Chae Gyu Park, Chae Gyu Park, Chae Gyu Park   +26 more
doaj   +1 more source

Induction of CD83+CD14+ Nondendritic Antigen-Presenting Cells by Exposure of Monocytes to IFN-α [PDF]

The Journal of Immunology, 2008
Abstract IFN-α is a well-known agent for treatment of viral and malignant diseases. It has several modes of actions, including direct influence on the immune system. We investigated IFN-α effects on PBMC in terms of dendritic cell (DC) differentiation, as PBMC are exposed to high IFN-α levels during treatment of infections and cancers.
Gerlini, Gianni, Mariotti, Giulia, Chiarugi, Alberto, Di Gennaro, Paola, Caporale, Roberto, Parenti, Astrid, Cavone, Leonardo, Tun-Kyi, Adrian, Prignano, Francesca, Saccardi, Riccardo, Borgognoni, Lorenzo, Pimpinelli, Nicola   +11 more
openaire   +3 more sources

Altered Frequency and Phenotype of HLA-G-Expressing DC-10 in Type 1 Diabetes Patients at Onset and in Subjects at Risk to Develop the Disease

Frontiers in Immunology, 2021
Type 1 diabetes (T1D) is a chronic autoimmune disease resulting in progressive destruction of β-cells. Several factors affecting lymphocyte and antigen-presenting cells, including dendritic cells (DCs), contribute to defective maintenance of tolerance in
Giada Amodio, Alessandra Mandelli, Rosalia Curto, Paola M. V. Rancoita, Angela Stabilini, Riccardo Bonfanti, Riccardo Bonfanti, Maurizio de Pellegrin, Emanuele Bosi, Emanuele Bosi, Emanuele Bosi, Clelia Di Serio, Manuela Battaglia, Silvia Gregori   +13 more
doaj   +1 more source

Targeting CD83 for the treatment of graft-versus-host disease [PDF]

, 2013
Graft-versus-host disease (GVHD) is a common and often fatal complication of bone marrow transplantation. Antigen-presenting cells from donor and recipient play a critical role in the initiation and maintenance of GVHD.
Wang, Xiongfei, Liu, Xiaosong, MING Q. WEI, Wei, Ming, XIAOSONG LIU, Wei, Ming Q, XIONGFEI WANG   +6 more
core   +1 more source

PHENOTYPIC PECULIARITIES OF DENDRITIС CELLS DIFFERENTIATED FROM BLOOD MONOCYTES IN PATIENTS WITH KIDNEY CANCER

Медицинская иммунология, 2018
The aim of the study was to investigate the phenotypic features of dendritic cell (DCs) differentiated from peripheral blood monocytes in patients with kidney cancer (KC).
A. A. Savchenko, A. G. Borisov, I. V. Kudryavtsev, I. I. Gvozdev, A. V. Moshev   +4 more
doaj   +1 more source

Expression and Immune Characterization of Major Histocompatibility Complex in Paralichthys olivaceus after Antigen Stimulation

Biology, 2023
The Major histocompatibility complex (Mhc) is an important molecule for antigen presenting and binds to T cell receptors, activating T lymphocytes and triggering specific immune responses.
Jing Xing, Zhaoxia An, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi, Wenbin Zhan   +5 more
doaj   +1 more source

Characterization of Co-Stimulatory Ligand CD80/86 and Its Effect as a Molecular Adjuvant on DNA Vaccine Against Vibrio anguillarum in Flounder (Paralichthys olivaceus)

Frontiers in Immunology, 2022
The CD80/86 molecule is one of the important co-stimulatory ligands and involves antigen-specific immune responses by ligating with CD28 and then delivering the required second signal to T-cell activation. In this study, a CD80/86 homolog was identified,
Wenjing Liu, Jing Xing, Jing Xing, Xiaoqian Tang, Xiaoqian Tang, Xiuzhen Sheng, Heng Chi, Wenbin Zhan, Wenbin Zhan   +8 more
doaj   +1 more source