Analysis of CD83 antigen expression in human breast fibroadenoma and adjacent tissue [PDF]
São Paulo Medical Journal, 2011 CONTEXT AND OBJECTIVE: Dendritic cell maturation is considered essential for starting an immune response. The CD83 antigen is an important marker of dendritic cell maturation.
Marcus Nascimento Borges +4 more
doaj +11 more sources
CD83 Antibody Inhibits Human B Cell Responses to Antigen as well as Dendritic Cell–Mediated CD4 T Cell Responses [PDF]
The Journal of Immunology, 2018 Abstract Anti-CD83 Ab capable of Ab-dependent cellular cytotoxicity can deplete activated CD83+ human dendritic cells, thereby inhibiting CD4 T cell–mediated acute graft-versus-host disease. As CD83 is also expressed on the surface of activated B lymphocytes, we hypothesized that anti-CD83 would also inhibit B cell responses to ...
Kuan Y Wong +5 more
core +8 more sources
Antibody to the dendritic cell surface activation antigen CD83 prevents acute graft-versus-host disease [PDF]
Journal of Experimental Medicine, 2009 Allogeneic (allo) hematopoietic stem cell transplantation is an effective therapy for hematological malignancies but it is limited by acute graft-versus-host disease (GVHD). Dendritic cells (DC) play a major role in the allo T cell stimulation causing GVHD.
Wilson, John +9 more
openaire +9 more sources
Inhibition of CD83 Alleviates Systemic Inflammation in Herpes Simplex Virus Type 1-Induced Behçet’s Disease Model Mouse [PDF]
Mediators of Inflammation, 2019 Behçet’s disease (BD) is an autoinflammatory disease that can lead to life- and sight-threating complications. Dendritic cells (DCs) are the most potent antigen-presenting cells that can regulate multiple inflammatory pathways.
S. M. Shamsul Islam +3 more
doaj +2 more sources
CD83 modulates B cell function in vitro: increased IL-10 and reduced Ig secretion by CD83Tg B cells. [PDF]
PLoS ONE, 2007 The murine transmembrane glycoprotein CD83 is an important regulator for both thymic T cell maturation and peripheral T cell responses. Recently, we reported that CD83 also has a function on B cells: Ubiquitous transgenic (Tg) expression of CD83 ...
Birte Kretschmer +7 more
doaj +2 more sources
Induction of foxp3 during the Crosstalk between Antigen Presenting Like-Cells MHCII+CD83+ and Splenocytes CD4+IgM− in Rainbow Trout [PDF]
Biology, 2021 In fish, the spleen is one of the major immune organs in the animal, and the splenocytes could play a key role in the activation and modulation of the immune response, both innate and adaptive. However, the crosstalk between different types of immune cells in the spleen has been poorly understood.
Morales-Lange, Byron +5 more
openaire +5 more sources
A-kinase anchoring in dendritic cells is required for antigen presentation. [PDF]
PLoS ONE, 2009 BACKGROUND: Dendritic cells (DC) are the most potent antigen presenting cells (APC) of the immune system. Prostaglandin E(2), cyclic AMP, and protein kinase A (PKA) have all been shown to regulate DC maturation and activity.
Robynn V Schillace +6 more
doaj +3 more sources
Recent advances in antigen targeting to antigen-presenting cells in veterinary medicine [PDF]
Frontiers in Immunology, 2023 Advances in antigen targeting in veterinary medicine have gained traction over the years as an alternative approach for diseases that remain a challenge for traditional vaccines.
Edgar Alonso Melgoza-González +2 more
doaj +3 more sources
CD83+ dendritic cells in ulcerative and Crohn's colitis [PDF]
, 2021 UVOD: Crohnova bolest (CD) i ulcerozni kolitis (UC) predstavljaju dva fenotipa upalnih bolesti crijeva (IBD). Dendritična stanica (DS), glavna antigen prezentirajuća stanica mukoze crijeva, važan je čimbenik u patogenezi IBD-a.
Rošić Despalatović, Bruna
core +4 more sources