Results 11 to 20 of about 448,583 (189)

Analysis of CD83 antigen expression in human breast fibroadenoma and adjacent tissue [PDF]

São Paulo Medical Journal, 2011
CONTEXT AND OBJECTIVE: Dendritic cell maturation is considered essential for starting an immune response. The CD83 antigen is an important marker of dendritic cell maturation.
Marcus Nascimento Borges, Gil Facina, Ismael Dale Cotrin Guerreiro Silva, Angela Flávia Logullo Waitzberg, Afonso Celso Pinto Nazario   +4 more
doaj   +8 more sources

Inhibition of CD83 Alleviates Systemic Inflammation in Herpes Simplex Virus Type 1-Induced Behçet’s Disease Model Mouse [PDF]

Mediators of Inflammation, 2019
Behçet’s disease (BD) is an autoinflammatory disease that can lead to life- and sight-threating complications. Dendritic cells (DCs) are the most potent antigen-presenting cells that can regulate multiple inflammatory pathways.
S. M. Shamsul Islam, Hae-Ok Byun, Bunsoon Choi, Seonghyang Sohn   +3 more
doaj   +2 more sources

CD83 Antibody Inhibits Human B Cell Responses to Antigen as well as Dendritic Cell–Mediated CD4 T Cell Responses [PDF]

The Journal of Immunology, 2018
Abstract Anti-CD83 Ab capable of Ab-dependent cellular cytotoxicity can deplete activated CD83+ human dendritic cells, thereby inhibiting CD4 T cell–mediated acute graft-versus-host disease. As CD83 is also expressed on the surface of activated B lymphocytes, we hypothesized that anti-CD83 would also inhibit B cell responses to ...
Kuan Y Wong, Rebecca Baron, Therese A Seldon, Martina L Jones, Alison M Rice, David J Munster   +5 more
core   +6 more sources

PHENOTYPIC PECULIARITIES OF DENDRITIС CELLS DIFFERENTIATED FROM BLOOD MONOCYTES IN PATIENTS WITH KIDNEY CANCER [PDF]

Медицинская иммунология, 2018
The aim of the study was to investigate the phenotypic features of dendritic cell (DCs) differentiated from peripheral blood monocytes in patients with kidney cancer (KC).
A. A. Savchenko, A. G. Borisov, I. V. Kudryavtsev, I. I. Gvozdev, A. V. Moshev   +4 more
doaj   +2 more sources

CD83 modulates B cell function in vitro: increased IL-10 and reduced Ig secretion by CD83Tg B cells.

PLoS ONE, 2007
The murine transmembrane glycoprotein CD83 is an important regulator for both thymic T cell maturation and peripheral T cell responses. Recently, we reported that CD83 also has a function on B cells: Ubiquitous transgenic (Tg) expression of CD83 ...
Birte Kretschmer, Katja Lüthje, Andreas H Guse, Svenja Ehrlich, Friedrich Koch-Nolte, Friedrich Haag, Bernhard Fleischer, Minka Breloer   +7 more
doaj   +2 more sources

Integrative Network Analysis and Machine Learning Identify Cell Adhesion-Related Biomarkers and Immune Heterogeneity in Allergic Rhinitis. [PDF]

Immun Inflamm Dis
ABSTRACT Background Allergic rhinitis (AR) represents a highly prevalent inflammatory disorder of the nasal mucosa, but molecular indicators capable of capturing its disease‐specific transcriptional features remain insufficiently defined. This study aimed to identify cell adhesion‐related diagnostic biomarkers for AR and to investigate their immune ...
He G, Zhang L.
europepmc   +2 more sources

Tolerogenic Programming Promotes Human Cytomegalovirus Permissiveness in Dendritic Cells. [PDF]

Eur J Immunol
Tolerogenic programming renders dendritic cells more permissive to HCMV infection and limits their capacity to stimulate T cells. These findings suggest that tolerogenic DCs serve as a permissive cellular niche that may facilitate HCMV immune evasion. ABSTRACT Dendritic cells (DCs) are important targets of human cytomegalovirus (HCMV), yet the factors ...
Rahmel-Stein K, Becker J, Lange B, Krajewski L, Eiz-Vesper B, Kalinke U.   +5 more
europepmc   +2 more sources

CD83-positive dendritic cells are present in occasional perivascular cuffs in multiple sclerosis lesions

, 2003
Multiple sclerosis (MS) has a wide spectrum of clinical courses, characterized by multifocal central nervous system (CNS) damage, postulated to be mediated by CNS antigen-specific T cells.
Plumb, J., Duddy, M., McQuaid, Stephen, Mirakhur, M., Armstrong, M. A.   +4 more
core   +6 more sources

Soluble CD83 alleviates experimental allergic rhinitis through modulating antigen-specific Th2 cell property [PDF]

International Journal of Biological Sciences, 2020
Background and aims: Dysfunction of the immune regulatory system plays a role in the pathogenesis of allergic rhinitis (AR). The underlying mechanism needs to be further investigated. Published data indicate that soluble CD83 (sCD83) has immune regulatory activities. This study aims to investigate the role of sCD83 in the alleviation of experimental AR.
Wu, Yong-Jin, Song, Yan-Nan, Geng, Xiao-Rui, Ma, Fei, Mo, Li-Hua, Zhang, Xiao-Wen, Liu, Da-Bo, Liu, Zhi-Gang, Yang, Ping-Chang   +8 more
openaire   +2 more sources

Induction of CD83+CD14+ Nondendritic Antigen-Presenting Cells by Exposure of Monocytes to IFN-α [PDF]

The Journal of Immunology, 2008
Abstract IFN-α is a well-known agent for treatment of viral and malignant diseases. It has several modes of actions, including direct influence on the immune system. We investigated IFN-α effects on PBMC in terms of dendritic cell (DC) differentiation, as PBMC are exposed to high IFN-α levels during treatment of infections and cancers.
Gerlini, Gianni, Mariotti, Giulia, Chiarugi, Alberto, Di Gennaro, Paola, Caporale, Roberto, Parenti, Astrid, Cavone, Leonardo, Tun-Kyi, Adrian, Prignano, Francesca, Saccardi, Riccardo, Borgognoni, Lorenzo, Pimpinelli, Nicola   +11 more
openaire   +3 more sources