Results 31 to 40 of about 15,671 (193)

Development of in vitro laboratory models of the tumor immune microenvironment to evaluate quality parameters and specific efficacy of the dendritic cell vaccine

Сибирский онкологический журнал, 2023
Purpose of the study: development of in vitro laboratory models to evaluate quality parameters and specific efficacy of dendritic cell vaccine (DCV).Material and Methods.
T. L. Nekhaeva, A. B. Danilova, E. I. Fedoros, N. A. Efremova, N. V. Emelyanova, M. L. Blokhina, M. N. Yurova, M. L. Tyndyk, I. A. Baldueva   +8 more
doaj   +1 more source

CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells [PDF]

International Immunology, 2007
CD83 is a member of the Ig superfamily expressed primarily by mature dendritic cells (DCs). In mice, CD83 expression by thymic stromal cells regulates CD4(+) T cell development, with CD83(-/-) mice demonstrating dramatic reductions in both thymus and peripheral CD4(+) T cells. In this study, CD83 expression was also found to affect MHC class II antigen
Yoshihiro, Kuwano, Charlene M, Prazma, Norihito, Yazawa, Rei, Watanabe, Nobuko, Ishiura, Atsushi, Kumanogoh, Hitoshi, Okochi, Kunihiko, Tamaki, Manabu, Fujimoto, Thomas F, Tedder   +9 more
openaire   +2 more sources

Characterization of dendritic cells and follicular dendritic cells in the hepatic lymph nodes and liver of sheep experimentally infected with Fasciola hepatica

Veterinary Research, 2020
Fasciola hepatica has been shown to have a high capacity for immunomodulation of the host response, making the development of protective vaccines extremely difficult.
María Teresa Ruiz-Campillo, Verónica Molina-Hernández, María José Bautista, Isabel L. Pacheco, Rafael Zafra, Leandro Buffoni, Francisco Javier Martínez-Moreno, Alvaro Martínez-Moreno, José Pérez   +8 more
doaj   +1 more source

Cancer cell immune mimicry delineates onco-immunologic modulation

iScience, 2021
Summary: Immune transcripts are essential for depicting onco-immunologic interactions. However, whether cancer cells mimic immune transcripts to reprogram onco-immunologic interaction remains unclear.
Rui Gao, Bin He, Qitao Huang, Zifeng Wang, Min Yan, Eric Wing-Fai Lam, Suxia Lin, Bo Wang, Quentin Liu   +8 more
doaj   +1 more source

Immunophenotyping of Sheep Paraffin-Embedded Peripheral Lymph Nodes

Frontiers in Immunology, 2018
Sheep are not only a major livestock species globally, they are also an important large animal model for biomedical research and have contributed to our understanding of the ontogeny and architecture of the mammalian immune system.
Eleonora Melzi, Mara S. Rocchi, Gary Entrican, Marco Caporale, Massimo Palmarini   +4 more
doaj   +1 more source

The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis

Frontiers in Immunology, 2022
Here we show that soluble CD83 induces the resolution of inflammation in an antigen-induced arthritis (AIA) model. Joint swelling and the arthritis-related expression levels of IL-1β, IL-6, RANKL, MMP9, and OC-Stamp were strongly reduced, while Foxp3 was
Dmytro Royzman, Darja Andreev, Lena Stich, Katrin Peckert-Maier, Andreas B. Wild, Elisabeth Zinser, Petra Mühl-Zürbes, Evan Jones, Susanne Adam, Silke Frey, Maximilian Fuchs, Meik Kunz, Meik Kunz, Tobias Bäuerle, Lisa Nagel, Georg Schett, Aline Bozec, Alexander Steinkasserer   +17 more
doaj   +1 more source

Expression of CD83 Is Regulated by HuR via a Novel cis-Active Coding Region RNA Element [PDF]

, 2006
Dendritic cells are the most potent of the antigen-presenting cells and are characterized by surface expression of CD83. Here, we show that the coding region of CD83 mRNA contains a novel cis-acting structured RNA element that binds to HuR, a member of ...
Susann Schirmer, Ines Langbein-Detsch, Joachim Hauber, Jörg Stülke, Kehlenbach, Ralph H., Alexander T. Prechtel, Ehlers, Christina, Prechtel, Alexander T., Christina Ehlers, Jan Chemnitz, Marie-Christine Dabauvalle, Langbein-Detsch, I., Chemnitz, J., Schirmer, S., Ralph H. Kehlenbach, Stulke, J., Dabauvalle, M. C., Hauber, J.   +17 more
core   +1 more source

Human Bone Marrow Mesenchymal Stromal/Stem Cells Regulate the Proinflammatory Response of Monocytes and Myeloid Dendritic Cells from Patients with Rheumatoid Arthritis

Pharmaceutics, 2022
Rheumatoid arthritis (RA) is a disabling autoimmune disease whose treatment is ineffective for one-third of patients. Thus, the immunomodulatory potential of mesenchymal stromal/stem cells (MSCs) makes MSC-based therapy a promising approach to RA.
Paula Laranjeira, Mónia Pedrosa, Cátia Duarte, Susana Pedreiro, Brígida Antunes, Tânia Ribeiro, Francisco dos Santos, António Martinho, Margarida Fardilha, M. Rosário Domingues, Manuel Abecasis, José António Pereira da Silva, Artur Paiva   +12 more
doaj   +1 more source

The effect of Propionibacterium acnes on maturation of dendritic cells derived from acne patients' peripherial blood mononuclear cells.

Folia Histochemica et Cytobiologica, 2009
Propionibacterium acnes (P. acnes) has been implicated in the pathogenesis of acne vulgaris which is the most common cutaneous disorder. It has a proinflammatory activity and takes part in immune reactions modulating the Th1/Th2 cellular response.
Maria Juszkiewicz-Borowiec, Alina Olender, Jacek Tabarkiewicz, Anna Michalak-Stoma, Filip Stoma, Aldona Pietrzak, Piotr Pozarowski, Małgorzata Bartkowiak-Emeryk   +7 more
doaj   +1 more source

Environmentally weathered polystyrene particles induce phenotypical and functional maturation of human monocyte-derived dendritic cells

Journal of Immunotoxicology, 2022
Micro- and nanoplastics (MNP) are ubiquitously present in the environment due to their high persistence and bioaccumulative properties. Humans get exposed to MNP via various routes and consequently, they will encounter dendritic cells (DC) which are ...
Annemijne E. T. van den Berg, Maud Plantinga, Dick Vethaak, Kas J. Adriaans, Marianne Bol-Schoenmakers, Juliette Legler, Joost J. Smit, Raymond H. H. Pieters   +7 more
doaj   +1 more source